References used in TopicalPdb

Title PMID
Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus. 27405275
Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8. 27189051
Self-adjuvanted hyaluronate--antigenic peptide conjugate for transdermal treatment of muscular dystrophy. 26724457
Iontophoretic skin permeation of peptides: an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters. 25786877
Role of the Na(+)/K(+)-ATPase beta-subunit in peptide-mediated transdermal drug delivery. 25734358
Anti-cancer vaccination by transdermal delivery of antigen peptide-loaded nanogels via iontophoresis. 25681719
Peptides as skin penetration enhancers: mechanisms of action. 25499919
Topical delivery of Cyclosporine A into the skin using SPACE-peptide. 25481447
Physicochemical characterization of native glycyl-l-histidyl-l-lysine tripeptide for wound healing and anti-aging: a preformulation study for dermal delivery. 25384620
Peptide-chaperone-directed transdermal protein delivery requires energy. 25269793
Controlled transdermal delivery of leuprorelin by pulsed iontophoresis and ion-exchange fiber. 25173088
Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial. 25041740
Enhanced transdermal peptide delivery and stability by lipid conjugation: epidermal permeation, stereoselectivity and mechanistic insights. 24842663
Therapeutic potential of the antimicrobial peptide OH-CATH30 for antibiotic-resistant Pseudomonas aeruginosa keratitis. 24637683
The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine. 24602570
Enhancement in deposition and permeation of 5-fluorouracil through human epidermis assisted by peptide dendrimers. 24134794
Physicochemical and biological characterization of pep-1/elastin complexes. 23601371
Effect of cationic cyclopeptides on transdermal and transmembrane delivery of insulin. 23391375
Transdermal delivery of human epidermal growth factor facilitated by a peptide chaperon. 23385091
Potent enhancement of transdermal absorption and stability of human tyrosinase plasmid (pAH7/Tyr) by Tat peptide and an entrapment in elastic cationic niosomes. 23311648
Dermal peptide delivery using enhancer molecules and colloidal carrier systems--part I: carnosine. 22890441
Intravitreal injection or topical eye-drop application of a μ-calpain C2L domain peptide protects against photoreceptor cell death in Royal College of Surgeons' rats, a model of retinitis pigmentosa. 22885154
Topical application of Sadat-Habdan mesenchymal stimulating peptide (SHMSP) accelerates wound healing in diabetic rabbits. 22778713
Enhanced skin permeation using polyarginine modified nanostructured lipid carriers. 22617521
Transdermal absorption and stability enhancement of salmon calcitonin by Tat peptide. 22564052
PEDF-derived peptide inhibits corneal angiogenesis by suppressing VEGF expression. 22386653
Penetratin-induced transdermal delivery from H(II) mesophases of sodium diclofenac. 22306174
Effect of silk fibroin peptide derived from silkworm Bombyx mori on the anti-inflammatory effect of Tat-SOD in a mice edema model. 22189681
Tat peptide-admixed elastic liposomal formulation of hirsutenone for the treatment of atopic dermatitis in NC/Nga mice. 22072881
A simple, noninvasive and efficient method for transdermal delivery of siRNA. 22009459
Identification of a novel peptide ligand targeting visceral adipose tissue via transdermal route by in vivo phage display. 21999821
Accelerated healing of diabetic wounds by NorLeu(3)-angiotensin (1-7). 21973177
Therapeutic effects on atopic dermatitis by anti-RelA short interfering RNA combined with functional peptides Tat and AT1002. 21531792
Topical flagellin-mediated innate defense against Candida albicans keratitis. 21310913
Development of an efficient transdermal delivery system of small interfering RNA using functional peptides, Tat and AT-1002. 21297299
Biphasic vesicles for topical delivery of interferon alpha in human volunteers and treatment of patients with human papillomavirus infections. 21291377
Therapeutic efficacy of halocidin-derived peptide HG1 in a mouse model of surgical wound infection with methicillin-resistant Staphylococcus aureus. 21220538
MITF-siRNA formulation is a safe and effective therapy for human melasma. 21119619
Transdermal absorption enhancement of N-terminal Tat-GFP fusion protein (TG) loaded in novel low-toxic elastic anionic niosomes. 20891012
Peptide-mediated transdermal delivery of botulinum neurotoxin type A reduces neurogenic inflammation in the skin. 20223589
H(II) mesophase and peptide cell-penetrating enhancers for improved transdermal delivery of sodium diclofenac. 20189781
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. 20089796
Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells. 19949052
Topical administration of cyclosporin A in a solid lipid nanoparticle formulation. 19746839
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. 19733297
Cell penetrating peptide POD mediates delivery of recombinant proteins to retina, cornea and skin. 19733192
Surface disinfection properties of the combination of an antimicrobial peptide, ranalexin, with an endopeptidase, lysostaphin, against methicillin-resistant Staphylococcus aureus (MRSA). 19709343
Stability of triptorelin in the presence of dermis and epidermis. 19486932
Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream. 18990064
Transdermal delivery of insulin using trypsin as a biochemical enhancer. 18670091
Biochemical enhancement of transdermal delivery with magainin peptide: modification of electrostatic interactions by changing pH. 18601987
LIGR, a protease-activated receptor-2-derived peptide, enhances skin pigmentation without inducing inflammatory processes. 18426410
Topical manganese peptide in the treatment of photodamaged skin. 18236243
Transdermal delivery of proteins mediated by non-covalently associated arginine-rich intracellular delivery peptides. 18031459
Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea. 17923842
Transdermal delivery enhanced by magainin pore-forming peptide. 17628164
Immunological activation following transcutaneous delivery of HR-gp100 protein. 17493711
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. 17307377
Liquid crystalline phases of monoolein and water for topical delivery of cyclosporin A: characterization and study of in vitro and in vivo delivery. 16621488
Transdermal protein delivery by a coadministered peptide identified via phage display. 16565728
Dipeptide monoester ganciclovir prodrugs for treating HSV-1-induced corneal epithelial and stromal keratitis: in vitro and in vivo evaluations. 16386088
Biomimetic delivery of keratinocyte growth factor upon cellular demand for accelerated wound healing in vitro and in vivo. 16314471
Topical combination of NGF and DHA increases rabbit corneal nerve regeneration after photorefractive keratectomy. 16123410
Topical application of a novel immunomodulatory peptide, RDP58, reduces skin inflammation in the phorbol ester-induced dermatitis model. 16117788
Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis. 16117784
Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice. 16113599
In vivo iontophoretic delivery and pharmacokinetics of salmon calcitonin. 15907605
Comparative study of the skin penetration of protein transduction domains and a conjugated peptide. 15906170
Dermal delivery of desmopressin acetate using colloidal carrier systems. 15831201
The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice. 15774286
A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses. 15734548
Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant. 15603887
Secretoneurin in the human aqueous humor and the absence of an effect of frequently used eye drops on the levels. 15572199
Transdermal delivery of desmopressin using a coated microneedle array patch system. 15212882
Antennapedia transduction sequence promotes anti tumour immunity to epicutaneously administered CTL epitopes. 15121311
Delivery and stability of LHRH and Nafarelin in human skin: the effect of constant/pulsed iontophoresis. 14757511
Topical PTH (1-34) is a novel, safe and effective treatment for psoriasis: a randomized self-controlled trial and an open trial. 12932245
Influence of molecular dipoles on human skin permeability: Use of 6-ketocholestanol to enhance the transdermal delivery of bacitracin. 12712421
Transdermal delivery of insulin from poloxamer gel: ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers. 12695068
Transdermal delivery of insulin from a novel biphasic lipid system in diabetic rats. 12396742
A retro-inverso peptide analogue of influenza virus hemagglutinin B-cell epitope 91-108 induces a strong mucosal and systemic immune response and confers protection in mice after intranasal immunization. 12220890
Transdermal insulin delivery using lipid enhanced electroporation. 12100989
Transdermal administration of salmon calcitonin by pulse depolarization-iontophoresis in rats. 11337153
Photomechanical transdermal delivery of insulin in vivo. 11295766
Biological effects after percutaneous absorption of thyrotropin-releasing hormone and its analogue M-TRH. 11179600
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation. 11062537
Effect of penetration enhancers on the permeation of the thyrotropin releasing hormone analogue pGlu-3-methyl-His-Pro amide through human epidermis. 10205635
In vitro and in vivo characterization of NK3 receptors in the rabbit eye by use of selective non-peptide NK3 receptor antagonists. 9351503
Potent pheromonotropic/myotropic activity of a carboranyl pseudotetrapeptide analogue of the insect pyrokinin/PBAN neuropeptide family administered via injection or topical application. 8844762
A comparison of morphological effects on the rabbit nasal and sinus mucosa after surgical denervation and topical capsaicin application. 8737771
Inhibition of bradykinin-evoked trigeminal nerve stimulation by the non-peptide bradykinin B2 receptor antagonist WIN 64338 in vivo and in vitro. 8719791
Substance P and nitric oxide mediate would healing of ultraviolet photodamaged rat skin: evidence for an effect of nitric oxide on keratinocyte proliferation. 8584255
Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl phorbol dermal application. 7646536
Rhinorrhea is decreased in dogs after nasal application of botulinum toxin. 7700663
Accelerated healing of chronic sickle-cell leg ulcers treated with RGD peptide matrix. RGD Study Group. 8080985
Stearyl-norleucine-vasoactive intestinal peptide (VIP): a novel VIP analog for noninvasive impotence treatment. 8156912
Effectiveness of the elcatonin transdermal system for the treatment of osteoporosis and the effect of the combination of elcatonin and active vitamin D3 in rat. 8268857
Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone. 8360818
Hydrogel-based iontotherapeutic delivery devices for transdermal delivery of peptide/protein drugs. 8321834
Capsaicin-desensitization to the human nasal mucosa selectively reduces pain evoked by citric acid. 8443036
Effects of topical capsaicin on autonomic nerves in experimentally-induced nasal hypersensitivity. An immunocytochemical study. 7680838
A fatty neuropeptide. Potential drug for noninvasive impotence treatment in a rat model. 1522236
Effect of iontophoresis on in vitro skin permeation of an analogue of growth hormone releasing factor in the hairless guinea pig model. 1403695
Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptides. 1373740
Bombesin stimulates human nasal mucous and serous cell secretion in vivo. 1733281
Percutaneous absorption of elcatonin and hypocalcemic effect in rat. 2054872
Transdermal delivery of bioactive peptides: the effect of n-decylmethyl sulfoxide, pH, and inhibitors on enkephalin metabolism and transport. 2293206
Inhibition of Pseudomonas aeruginosa elastase and Pseudomonas keratitis using a thiol-based peptide. 2127341
Transdermal versus subcutaneous leuprolide: a comparison of acute pharmacodynamic effect. 2121407
Stimulation of tear secretion by topical agents that increase cyclic nucleotide levels. 2365569
Iontophoresis of polypeptides: effect of ethanol pretreatment of human skin. 2118954
Transdermal iontophoresis of gonadotropin releasing hormone (LHRH) and two analogues. 2203894
In vitro transdermal delivery of a melanotropic peptide through human skin. 2155969
Mouse epidermal cell renewal after topical treatment with different concentrations of the epidermal peptide pyroGlu-Glu-Asp-Ser-GlyOH. 1977237
Systemic and intraocular uptake of spantide, a tachykinin antagonist, following topical application to the rabbit eye. 1689665
Capsaicin evokes secretion of nasal fluid and depletes substance P and calcitonin gene-related peptide from the nasal mucosa in the rat. 2480171
Alpha-melanocyte stimulating hormone modulates contact hypersensitivity responsiveness in C57/BL6 mice. 2550560
Transdermal peptide delivery. 2533571
Direct current iontophoretic transdermal delivery of peptide and protein drugs. 2664126
Transdermal iontophoretic drug delivery: mechanistic analysis and application to polypeptide delivery. 2664125
Successful transdermal administration of therapeutic doses of a polypeptide to normal human volunteers. 3143511
CGRP in relation to neurogenic inflammation and cAMP in the rabbit eye. 2842178
Effect of neurogenic irritation and calcitonin gene-related peptide (CGRP) on ocular blood flow in the rabbit. 3262039
Secretion, pain and sneezing induced by the application of capsaicin to the nasal mucosa in man. 3370386
Transdermal delivery of a melanotropic peptide hormone analogue. 2845208
Stimulation of follicular melanogenesis in the mouse by topical and injected melanotropins. 3624899
Topical application of a melanotropic peptide induces systemic follicular melanogenesis. 3573985
Facilitated transdermal transport of insulin. 3298619
Metastases of renal adenocarcinoma to the larynx and paranasal sinuses. 3684299
Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised nude mouse skin. 3095533
Control of blood glucose levels in alloxan-diabetic rabbits by iontophoresis of insulin. 3510926
Metabolic and permeation barriers to the ocular absorption of topically applied enkephalins in albino rabbits. 3503119
Enhancement of host resistance against virus infections by MTP-PE, a synthetic lipophilic muramyl peptide--I. Increased survival in mice and guinea pigs after single drug administration prior to infection, and the effect of MTP-PE on interferon levels in sera and lungs. 2433236
Penetration of topical cyclosporine into the rabbit cornea, aqueous humor, and serum. 3977661
Insulin iontophoresis in cystic fibrosis. 1144451