Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_0860β -1,3-glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalβ-glucan binds to the LGBP and induce innate immunityLipopolysaccharide and b-1, 3-glucan binding protein (LGBP)Pattern recognition receptor (PRR)Chlamys farreriHemocytes, gills and mantleNANANANAIt is involved in pathogens recognition and bacterial agglutination.NA206595622010NA
PRRID_0860β -1,3-glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalβ-glucan binds to the LGBP and induce innate immunityLipopolysaccharide and b-1, 3-glucan binding protein (LGBP)Pattern recognition receptor (PRR)Chlamys farreriHemocytes, gills and mantleNANANANAIt is involved in pathogens recognition and bacterial agglutination.NA206595622010NA
PRRID_0861β -1,3-glucan

Click for more detail

P. pastoris (fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalβ-glucan binds to the LGBP and induce innate immunityLipopolysaccharide and b-1, 3-glucan binding protein (LGBP)Pattern recognition receptor (PRR)Chlamys farreriHemocytes, gills and mantleNANANANAIt is involved in pathogen recognition and it's clearanceNA206595622010NA
PRRID_0861β -1,3-glucan

Click for more detail

P. pastoris (fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalβ-glucan binds to the LGBP and induce innate immunityLipopolysaccharide and b-1, 3-glucan binding protein (LGBP)Pattern recognition receptor (PRR)Chlamys farreriHemocytes, gills and mantleNANANANAIt is involved in pathogen recognition and it's clearanceNA206595622010NA
PRRID_0862β -1,3-glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNAGmCP10Pattern recognition receptor (PRR)Galleria mellonellahemolymphNANANANAIt has opsonin activity for the phagocytosis of the microorganisms by hemocytes.NA205195172010NA
PRRID_0862β -1,3-glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNAGmCP10Pattern recognition receptor (PRR)Galleria mellonellahemolymphNANANANAIt has opsonin activity for the phagocytosis of the microorganisms by hemocytes.NA205195172010NA
PRRID_10201,3 beta glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanHEK293 cellsNAO60603.fastaO60603784triggers the MyD88-dependent signaling pathway, leading to NF-kB activationNF-240985082013Pubchem Assay
PRRID_10201,3 beta glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanHEK293 cellsNAO60603.fastaO60603784triggers the MyD88-dependent signaling pathway, leading to NF-kB activationNF-240985082013Pubchem Assay
PRRID_1051Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseCgToll-like receptor 3 (TLR3)Toll-like receptor (TLR)C. gigasHEK293 cellsNANANANANANF-240985082013NA
PRRID_1051Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseCgToll-like receptor 3 (TLR3)Toll-like receptor (TLR)C. gigasHEK293 cellsNANANANANANF-240985082013NA
PRRID_1053Glycolipids

Click for more detail

Treponema maltophilum (others)NANACarbohydrateNaturaltriggers immune responsesToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micemonocyte/macrophages, DCs, B-lymphocytesextracellular domains of leucine-rich repeat motifs Q9QUN7.fastaQ9QUN7784significant role in the pathogenesis of severe inflammatory responses NA239853022013Pubchem_assay
PRRID_1053Glycolipids

Click for more detail

Treponema maltophilum (others)NANACarbohydrateNaturaltriggers immune responsesToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micemonocyte/macrophages, DCs, B-lymphocytesextracellular domains of leucine-rich repeat motifs Q9QUN7.fastaQ9QUN7784significant role in the pathogenesis of severe inflammatory responses NA239853022013Pubchem_assay
PRRID_1138Serum amyloid

Click for more detail

Endogenous (others)MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY122CarbohydrateNaturalelicit innate immune responseToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micemonocyte/macrophages, DCs, B-lymphocytesextracellular domains of leucine-rich repeat motifs Q9QUN7.fastaQ9QUN7784significant role in the pathogenesis of severe inflammatory responses NA239853022013Pubchem_assay
PRRID_1138Serum amyloid

Click for more detail

Endogenous (others)MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY122CarbohydrateNaturalelicit innate immune responseToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Micemonocyte/macrophages, DCs, B-lymphocytesextracellular domains of leucine-rich repeat motifs Q9QUN7.fastaQ9QUN7784significant role in the pathogenesis of severe inflammatory responses NA239853022013Pubchem_assay
PRRID_1227Curdlan

Click for more detail

BacteriaNANACarbohydrateSyntheticused in gel productionDectin-1C type Lectin (CTL/CLR)European and African ChildrenNANAQ9BXN2.fastaQ9BXN2247Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationELISA247435422014Pubchem_assay
PRRID_1227Curdlan

Click for more detail

BacteriaNANACarbohydrateSyntheticused in gel productionDectin-1C type Lectin (CTL/CLR)European and African ChildrenNANAQ9BXN2.fastaQ9BXN2247Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammationELISA247435422014Pubchem_assay
PRRID_1469D-mannose

Click for more detail

BacteriaC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalNAERGIC-53Pattern recognition receptor (PRR)NANANANANANANANA247968682014NA
PRRID_1469D-mannose

Click for more detail

BacteriaC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalNAERGIC-53Pattern recognition receptor (PRR)NANANANANANANANA247968682014NA
PRRID_1497N-glycolylated muramic acid

Click for more detail

Mycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNACarbohydrateNaturalactivates NOD2Nod-like receptor 1 (NLR1)NOD-like receptor (NLR)Miceimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gutintracellular receptorsQ8K3Z0.fastaQ8K3Z01020Nod2, are associ- ated with inflammatory bowel disease in humansNA247793902014Pubchem_assay
PRRID_1497N-glycolylated muramic acid

Click for more detail

Mycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNACarbohydrateNaturalactivates NOD2Nod-like receptor 1 (NLR1)NOD-like receptor (NLR)Miceimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gutintracellular receptorsQ8K3Z0.fastaQ8K3Z01020Nod2, are associ- ated with inflammatory bowel disease in humansNA247793902014Pubchem_assay
PRRID_1498N-glycolylated muramic acid

Click for more detail

Mycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNACarbohydrateNaturalactivates NOD2Nod-like receptor 1 (NLR1)NOD-like receptor (NLR)Humanimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gutintracellular receptorsQ9HC29.fastaQ9HC291040Nod2, are associ- ated with inflammatory bowel disease in humansNA247793902014Pubchem_assay
PRRID_1498N-glycolylated muramic acid

Click for more detail

Mycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNACarbohydrateNaturalactivates NOD2Nod-like receptor 1 (NLR1)NOD-like receptor (NLR)Humanimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gutintracellular receptorsQ9HC29.fastaQ9HC291040Nod2, are associ- ated with inflammatory bowel disease in humansNA247793902014Pubchem_assay
PRRID_1510D-mannose

Click for more detail

BacteriaC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalNAVIP36Pattern recognition receptor (PRR)NANANANANANANANA247968682014NA
PRRID_1510D-mannose

Click for more detail

BacteriaC(C1C(C(C(C(O1)O)O)O)O)ONACarbohydrateNaturalNAVIP36Pattern recognition receptor (PRR)NANANANANANANANA247968682014NA
PRRID_1590polysaccharides (MAMPs)

Click for more detail

BacteriaNANACarbohydrateNaturalNACalnexin (Cnx)Pattern recognition receptor (PRR)Marsupenaeus japonicustransmembrane chaperoneNANANANANANA248580312014NA
PRRID_1590polysaccharides (MAMPs)

Click for more detail

BacteriaNANACarbohydrateNaturalNACalnexin (Cnx)Pattern recognition receptor (PRR)Marsupenaeus japonicustransmembrane chaperoneNANANANANANA248580312014NA
PRRID_1694Fucoidan

Click for more detail

NACC1C(C(C(C(O1)C)OS(=O)(=O)O)O)ONACarbohydrateNaturalImmunostimulantLvLGBPPattern recognition receptor (PRR)Litopenaeus vannameiHemocytesNANANANAcause degranulation, and activate the proPO system that subsequently leads to an increase in PO activity, indicating the activation of innate immunity.ELISA265223392015NA
PRRID_1694Fucoidan

Click for more detail

NACC1C(C(C(C(O1)C)OS(=O)(=O)O)O)ONACarbohydrateNaturalImmunostimulantLvLGBPPattern recognition receptor (PRR)Litopenaeus vannameiHemocytesNANANANAcause degranulation, and activate the proPO system that subsequently leads to an increase in PO activity, indicating the activation of innate immunity.ELISA265223392015NA
PRRID_1742Fucose

Click for more detail

HIV-1 (virus)CC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1742Fucose

Click for more detail

HIV-1 (virus)CC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1743Fucose

Click for more detail

S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusCC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1743Fucose

Click for more detail

S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusCC(C(C(C(C=O)O)O)O)ONACarbohydrateNaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1745Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalIt enhances microbe agglutination and haemocytes encapsulation.GalectinPattern recognition receptor (PRR)Eriocheir sinensisHepatopancreasCRDNANANAIt provies immune defense against invading microbes.ELISA270951742016NA
PRRID_1745Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalIt enhances microbe agglutination and haemocytes encapsulation.GalectinPattern recognition receptor (PRR)Eriocheir sinensisHepatopancreasCRDNANANAIt provies immune defense against invading microbes.ELISA270951742016NA
PRRID_1781Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNACfLRRop-3Leucine rich repeats (LRR)NANANANANANANANA268264252016NA
PRRID_1781Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNACfLRRop-3Leucine rich repeats (LRR)NANANANANANANANA268264252016NA
PRRID_18901,3 beta glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRMiceNANAQ6QLQ4.fastaQ6QLQ4244protective role in infection modelNA281676512017Pubchem_assay
PRRID_18901,3 beta glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRMiceNANAQ6QLQ4.fastaQ6QLQ4244protective role in infection modelNA281676512017Pubchem_assay
PRRID_18911,3 beta glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRHumanNANAQ9BXN2.fastaQ9BXN2247protective role in infection modelNA281676512017Pubchem_assay
PRRID_18911,3 beta glucan

Click for more detail

Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRHumanNANAQ9BXN2.fastaQ9BXN2247protective role in infection modelNA281676512017Pubchem_assay
PRRID_18921,3 beta glucan

Click for more detail

FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA272884072017NA
PRRID_18921,3 beta glucan

Click for more detail

FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA272884072017NA
PRRID_1957Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityToll-like receptor 2 (TLR2)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1957Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityToll-like receptor 2 (TLR2)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1958Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1958Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1959Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1959Biglycan

Click for more detail

Proteoglycan (others)MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA292901392017NA
PRRID_1960Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMacrophagesLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784NANA289610192017Pubchem_assay
PRRID_1960Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesToll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMacrophagesLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784NANA289610192017Pubchem_assay
PRRID_1961Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMacrophagesQ9QUK6Q9QUK6.fastaQ9QUK6835NANA289610192017Pubchem_assay
PRRID_1961Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMacrophagesQ9QUK6Q9QUK6.fastaQ9QUK6835NANA289610192017Pubchem_assay
PRRID_1962Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMacrophagesNAQ8R4B8.fastaQ8R4B81033NANA289610192017Pubchem_assay
PRRID_1962Biglycan

Click for more detail

NAMWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT238CarbohydrateNaturalInduce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophagesNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMacrophagesNAQ8R4B8.fastaQ8R4B81033NANA289610192017Pubchem_assay
PRRID_2073Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseAmphiCTL1C type Lectin (CTL/CLR)B. belcheriNANANANANANANA290551892017NA
PRRID_2073Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseAmphiCTL1C type Lectin (CTL/CLR)B. belcheriNANANANANANANA290551892017NA
PRRID_2074Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2074Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2075Glucan

Click for more detail

NAC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorCgLRRIG-1Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2075Glucan

Click for more detail

NAC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorCgLRRIG-1Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2076Glucan

Click for more detail

NAC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorCgLRRIG-2Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2076Glucan

Click for more detail

NAC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorCgLRRIG-2Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2077Glucan

Click for more detail

FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2077Glucan

Click for more detail

FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2078Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRMiceNANAQ6QLQ4.fastaQ6QLQ4244Protective role in infection modelNA281676512017Pubchem_assay
PRRID_2078Glucan

Click for more detail

S. cerevisiae (Bacteria)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRMiceNANAQ6QLQ4.fastaQ6QLQ4244Protective role in infection modelNA281676512017Pubchem_assay
PRRID_2082Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2082Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2084Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_2084Glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_27001,3 beta glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNAb-1,3-glucan recognition proteinsGastrin-releasing peptide receptor (GRP)NANANANANANANANA290322412018NA
PRRID_27001,3 beta glucan

Click for more detail

BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNAb-1,3-glucan recognition proteinsGastrin-releasing peptide receptor (GRP)NANANANANANANANA290322412018NA
PRRID_2706β-glucan

Click for more detail

gram-negative bacteria, fungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNArSgSABL-1LectinsNANANANANANAinduces pro-inflammatory cytokine responseNA291464482018NA
PRRID_2706β-glucan

Click for more detail

gram-negative bacteria, fungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalNArSgSABL-1LectinsNANANANANANAinduces pro-inflammatory cytokine responseNA291464482018NA
PRRID_2709N-acetyl or N-glycolyl

Click for more detail

NANANACarbohydrateNaturalNASialic acid-binding lectins (SABLs)LectinsNANANANANANAinduces pro-inflammatory cytokine responseNA291464482018NA
PRRID_2709N-acetyl or N-glycolyl

Click for more detail

NANANACarbohydrateNaturalNASialic acid-binding lectins (SABLs)LectinsNANANANANANAinduces pro-inflammatory cytokine responseNA291464482018NA