Detailed description page of PRRDB2.0

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PRRID_1497 details
Primary information
PRRIDPRRID_1497
Ligand NameN-glycolylated muramic acid
SourceMycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypeCarbohydrate
OccurenceNatural
Role of Ligandactivates NOD2
Name of receptorNod-like receptor 1 (NLR1)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gut
Domainintracellular receptors
Sequence of ReceptorQ8K3Z0.fasta
Swiss prot IDQ8K3Z0
Length Of Receptor1020
FunctionNod2, are associ- ated with inflammatory bowel disease in humans
Assay usedNA
PMID24779390
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1497
Ligand NameN-glycolylated muramic acid
SourceMycobacterium smegmatis and Mycobacterium tuberculosis (Bacteria)
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypeCarbohydrate
OccurenceNatural
Role of Ligandactivates NOD2
Name of receptorNod-like receptor 1 (NLR1)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationimmune cells like peripheral blood monocytes, granulocytes and dendritic cells, as well as in astrocytes of the brain and in paneth cells of the gut
Domainintracellular receptors
Sequence of ReceptorQ8K3Z0.fasta
Swiss prot IDQ8K3Z0
Length Of Receptor1020
FunctionNod2, are associ- ated with inflammatory bowel disease in humans
Assay usedNA
PMID24779390
Year of Publication2014
Pubchem assayPubchem_assay