Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0053 | MALP-2 (macrophage-activating lipopeptide 2) Click for more detail | Mycoplasma (Bacteria) | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8549669 | 1996 | NA |
| PRRID_0053 | MALP-2 (macrophage-activating lipopeptide 2) Click for more detail | Mycoplasma (Bacteria) | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8549669 | 1996 | NA |
| PRRID_0074 | Peptidoglycan (PGN) Click for more detail | S. aureus (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Peptidoglycan recognition by TLR 2 leads to the activation of NF-KB, which leads to the secretion of proinflammatory cytokines. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | TLR2 is responsible for recognzing the cell wall components of the gram-positive bacteria and induces the respective immune response. | EMSA | 10384090 | 1999 | Pubchem Assay |
| PRRID_0074 | Peptidoglycan (PGN) Click for more detail | S. aureus (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Peptidoglycan recognition by TLR 2 leads to the activation of NF-KB, which leads to the secretion of proinflammatory cytokines. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | TLR2 is responsible for recognzing the cell wall components of the gram-positive bacteria and induces the respective immune response. | EMSA | 10384090 | 1999 | Pubchem Assay |
| PRRID_0075 | pneumolysin Click for more detail | S. pneumoniae (Bacteria) | MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND | 471 | NA | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | ytokine induction is mediated through NF-kappaB activation | NA | 10411278 | 1999 | Pubchem Assay |
| PRRID_0075 | pneumolysin Click for more detail | S. pneumoniae (Bacteria) | MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND | 471 | NA | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | ytokine induction is mediated through NF-kappaB activation | NA | 10411278 | 1999 | Pubchem Assay |
| PRRID_0081 | CpG DNA Click for more detail | Bacteria | NA | NA | Nucleic Acid | Natural | elicit innate immune response | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | NA | Q9NR96.fasta | Q9NR96 | 1032 | induce type I interferons (IFN) and other cytokines production. | NA | 11130078 | 2000 | Pubchem Assay |
| PRRID_0081 | CpG DNA Click for more detail | Bacteria | NA | NA | Nucleic Acid | Natural | elicit innate immune response | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | NA | Q9NR96.fasta | Q9NR96 | 1032 | induce type I interferons (IFN) and other cytokines production. | NA | 11130078 | 2000 | Pubchem Assay |
| PRRID_0097 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0097 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0098 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 2/6 (TLR2/6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0098 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 2/6 (TLR2/6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0100 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | NA | tandem mass spectrometry | 0 | 2001 | Pubchem Assay |
| PRRID_0100 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | NA | tandem mass spectrometry | 0 | 2001 | Pubchem Assay |
| PRRID_0105 | MALP-2 (macrophage-activating lipopeptide 2) Click for more detail | Mycoplasma (Bacteria) | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0105 | MALP-2 (macrophage-activating lipopeptide 2) Click for more detail | Mycoplasma (Bacteria) | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N | NA | Lipopeptides | Natural | Immunostimulant | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 11431423 | 2001 | NA |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0128 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Microvascular endothelial cells | LRR | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0128 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Microvascular endothelial cells | LRR | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0129 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | 5MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0129 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | 5MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0134 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0134 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0136 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0136 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0140 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0140 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0141 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0141 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0142 | Neisserial porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | It leads to the induction of NF-kappaB nuclear translocation. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | It has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2. | NF-kB luciferase reporter assay | 11823477 | 2002 | Pubchem Assay |
| PRRID_0142 | Neisserial porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | It leads to the induction of NF-kappaB nuclear translocation. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | It has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2. | NF-kB luciferase reporter assay | 11823477 | 2002 | Pubchem Assay |
| PRRID_0143 | OspA Click for more detail | Borrelia burgdorferi(Bacteria) | MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGGMTVLVSKEKDKDGKYSLDATVDKLELKGTSDKNNGSGTLEGEKTDKSKVKLTIADDLSQTKFEIFKEDGKTLVSKKVTLKDKSSTEEKFNEKGETSEKTIVRANGTRLEYTDIKSDGSGKAKEVLKDFTLEGTLAADGKTTLKVTEGTVVLSKNILKSGEITVALDDSDTTQATKKTGNWDSKSSTLTISVNSQKTKNLVFTKEDTITVQKYDSAGTNLEGKAVEITTLKELKAALK | NA | Lipoprotein | Natural | immunostimulantt | Toll-like receptor 2 (TLR2)+unknown | Toll-like receptor (TLR) | Human | NA | NA | NA | NA | NA | human hyporesponsiveness to OspA vaccination | NA | 12091878 | 2002 | NA |
| PRRID_0143 | OspA Click for more detail | Borrelia burgdorferi(Bacteria) | MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGGMTVLVSKEKDKDGKYSLDATVDKLELKGTSDKNNGSGTLEGEKTDKSKVKLTIADDLSQTKFEIFKEDGKTLVSKKVTLKDKSSTEEKFNEKGETSEKTIVRANGTRLEYTDIKSDGSGKAKEVLKDFTLEGTLAADGKTTLKVTEGTVVLSKNILKSGEITVALDDSDTTQATKKTGNWDSKSSTLTISVNSQKTKNLVFTKEDTITVQKYDSAGTNLEGKAVEITTLKELKAALK | NA | Lipoprotein | Natural | immunostimulantt | Toll-like receptor 2 (TLR2)+unknown | Toll-like receptor (TLR) | Human | NA | NA | NA | NA | NA | human hyporesponsiveness to OspA vaccination | NA | 12091878 | 2002 | NA |
| PRRID_0165 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0165 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0173 | iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail | Bacteria | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0173 | iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail | Bacteria | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0174 | Lewis x Click for more detail | H. pylori (Bacteria) | CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)O | NA | Carbohydrate | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0174 | Lewis x Click for more detail | H. pylori (Bacteria) | CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)CO)O)NC(=O)C)O)O)O | NA | Carbohydrate | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0176 | Lipopolysaccharide (LPS) Click for more detail | H. pylori (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0176 | Lipopolysaccharide (LPS) Click for more detail | H. pylori (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0179 | Mannose capped lipoarabinomannan Click for more detail | Mycobacterium tuberculosis (Bacteria) | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0179 | Mannose capped lipoarabinomannan Click for more detail | Mycobacterium tuberculosis (Bacteria) | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Synthetic | It strongly binds to the DC-SIGN. | DC-SIGN | C type Lectin (CTL/CLR) | K562 cells | Dendritic cells | Lectin domain | NA | NA | NA | It induces the pathogen-driven inflammatory responses. | ELISA | 12574325 | 2003 | NA |
| PRRID_0182 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0182 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0183 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0183 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0184 | PIM6 Click for more detail | Mycobacterium bovis Bacillus Calmette Guerin (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0184 | PIM6 Click for more detail | Mycobacterium bovis Bacillus Calmette Guerin (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0185 | PIM6 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0185 | PIM6 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0187 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0187 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0188 | Tri-DAP (L-Ala-D-g-Glu-mDAP) Click for more detail | Bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activation of the NF-κB pro-inflammatory cascade | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | Macrophages | NA | Q9Y239.fasta | Q9Y239 | 953 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | NA | 12527755 | 2003 | Pubchem Assay |
| PRRID_0188 | Tri-DAP (L-Ala-D-g-Glu-mDAP) Click for more detail | Bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activation of the NF-κB pro-inflammatory cascade | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | Macrophages | NA | Q9Y239.fasta | Q9Y239 | 953 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | NA | 12527755 | 2003 | Pubchem Assay |
| PRRID_0189 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | DC-SIGN | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0189 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | DC-SIGN | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0190 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | DC-SIGNR | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0190 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | DC-SIGNR | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0191 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | mSIGN-R1 | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0191 | (man)3-ara Click for more detail | Mycobacteria (Bacteria) | NA | NA | Carbohydrate | Natural | elicit innate immune response | mSIGN-R1 | C type Lectin (CTL/CLR) | THP-1 and K562 | NA | NA | NA | NA | NA | It inhibits the immuno-stimulatory function of dendritic cells. | ELISA | 15481146 | 2004 | NA |
| PRRID_0206 | Not Determined Click for more detail | Uropathogenic E.coli (Bacteria) | NA | NA | Others | Natural | elicit innate immune response | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Human | macrophages and liver, kidney, and bladder epithelial cells | NA | NA | NA | NA | NA | NA | 15001781 | 2004 | NA |
| PRRID_0206 | Not Determined Click for more detail | Uropathogenic E.coli (Bacteria) | NA | NA | Others | Natural | elicit innate immune response | Toll-like receptor 10 (TLR10) | Toll-like receptor (TLR) | Human | macrophages and liver, kidney, and bladder epithelial cells | NA | NA | NA | NA | NA | NA | 15001781 | 2004 | NA |
| PRRID_0207 | Opacity protein Click for more detail | Neisseria meningitidis (Bacteria) | MNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF | 273 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0207 | Opacity protein Click for more detail | Neisseria meningitidis (Bacteria) | MNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF | 273 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0208 | Porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0208 | Porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | elicit innate immune response | Mannose-binding lectins | Mannose receptor (MR) | Human | NA | NA | B1PN75.fasta | B1PN75 | 38 | MBL binding to N. meningitidis and increases complement activation and killing of organisms. | ELISA | 15004183 | 2004 | Pubchem Assay |
| PRRID_0219 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocytic cell line | extracellular leucine-rich mo- tifs, and a cytoplasmic domain called the Toll/IL-1R homology domain | NA | NA | NA | TLR2 is involved in the specific recognition of a wide range of ligands, either as a homodimer or as a heterodimer with TLR1 or TLR6. | ELISA | 15661917 | 2005 | NA |
| PRRID_0219 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipopeptides | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocytic cell line | extracellular leucine-rich mo- tifs, and a cytoplasmic domain called the Toll/IL-1R homology domain | NA | NA | NA | TLR2 is involved in the specific recognition of a wide range of ligands, either as a homodimer or as a heterodimer with TLR1 or TLR6. | ELISA | 15661917 | 2005 | NA |
| PRRID_0228 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0228 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0229 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0229 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0230 | Seeligeriolysin O (rLSO530) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0230 | Seeligeriolysin O (rLSO530) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0231 | Seeligeriolysin O (rLSO530) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0231 | Seeligeriolysin O (rLSO530) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0240 | CpG-ODNs Click for more detail | Bacteria | NA | NA | Nucleic Acid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | C57BL/6 mice | spleen cells | NA | Q9NR96.fasta | Q9NR96 | 1032 | induces pro-inflammatory cytokine response | ELISPOT | 16678312 | 2006 | Pubchem Assay |
| PRRID_0240 | CpG-ODNs Click for more detail | Bacteria | NA | NA | Nucleic Acid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | C57BL/6 mice | spleen cells | NA | Q9NR96.fasta | Q9NR96 | 1032 | induces pro-inflammatory cytokine response | ELISPOT | 16678312 | 2006 | Pubchem Assay |
| PRRID_0254 | Lipopolysaccharide (LPS) Click for more detail | enterobacterial bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | induces a strong response from normal animal immune systems | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Peripheral blood mononuclear cells (PBMC) | cytoplasmic leucine rich repeat (LRR) | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 17353199 | 2007 | Pubchem Assay |
| PRRID_0254 | Lipopolysaccharide (LPS) Click for more detail | enterobacterial bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | induces a strong response from normal animal immune systems | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Peripheral blood mononuclear cells (PBMC) | cytoplasmic leucine rich repeat (LRR) | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 17353199 | 2007 | Pubchem Assay |
| PRRID_0255 | Lipopolysaccharide (LPS) Click for more detail | E.coli strain O111:B4(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | induces a strong response from normal animal immune systems | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Peripheral blood mononuclear cells (PBMC) | cytoplasmic leucine rich repeat (LRR) | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 17353199 | 2007 | Pubchem Assay |
| PRRID_0255 | Lipopolysaccharide (LPS) Click for more detail | E.coli strain O111:B4(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | induces a strong response from normal animal immune systems | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Peripheral blood mononuclear cells (PBMC) | cytoplasmic leucine rich repeat (LRR) | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 17353199 | 2007 | Pubchem Assay |