Detailed description page of PRRDB2.0

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PRRID_0142 details
Primary information
PRRIDPRRID_0142
Ligand NameNeisserial porins
SourceNeisseria meningitidis (Bacteria)
Sequence of ligandMRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF
Length396
TypeProtein
OccurenceNatural
Role of LigandIt leads to the induction of NF-kappaB nuclear translocation.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationDendritic cells
DomainLRR
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2.
Assay usedNF-kB luciferase reporter assay
PMID11823477
Year of Publication2002
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0142
Ligand NameNeisserial porins
SourceNeisseria meningitidis (Bacteria)
Sequence of ligandMRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF
Length396
TypeProtein
OccurenceNatural
Role of LigandIt leads to the induction of NF-kappaB nuclear translocation.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationDendritic cells
DomainLRR
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2.
Assay usedNF-kB luciferase reporter assay
PMID11823477
Year of Publication2002
Pubchem assayPubchem Assay