| Primary information |
|---|
| PRRID | PRRID_0230 |
| Ligand Name | Seeligeriolysin O (rLSO530) |
| Source | Listeria seeligeri (Bacteria) |
| Sequence of ligand | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ |
| Length | 530 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | This leads to the inflammatory response. |
| Assay used | Transfection and nuclear factor j-B reporter assay |
| PMID | 16291660 |
| Year of Publication | 2005 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0230 |
| Ligand Name | Seeligeriolysin O (rLSO530) |
| Source | Listeria seeligeri (Bacteria) |
| Sequence of ligand | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ |
| Length | 530 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | This leads to the inflammatory response. |
| Assay used | Transfection and nuclear factor j-B reporter assay |
| PMID | 16291660 |
| Year of Publication | 2005 |
| Pubchem assay | Pubchem Assay |