Primary information |
---|
PRRID | PRRID_0231 |
Ligand Name | Seeligeriolysin O (rLSO530) |
Source | Listeria seeligeri (Bacteria) |
Sequence of ligand | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ |
Length | 530 |
Type | Protein |
Occurence | Natural |
Role of Ligand | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | Macrophages |
Domain | NA |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | This leads to the inflammatory response. |
Assay used | Transfection and nuclear factor j-B reporter assay |
PMID | 16291660 |
Year of Publication | 2005 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0231 |
Ligand Name | Seeligeriolysin O (rLSO530) |
Source | Listeria seeligeri (Bacteria) |
Sequence of ligand | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ |
Length | 530 |
Type | Protein |
Occurence | Natural |
Role of Ligand | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice |
Localization | Macrophages |
Domain | NA |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | This leads to the inflammatory response. |
Assay used | Transfection and nuclear factor j-B reporter assay |
PMID | 16291660 |
Year of Publication | 2005 |
Pubchem assay | Pubchem Assay |