Detailed description page of PRRDB2.0

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PRRID_0207 details
Primary information
PRRIDPRRID_0207
Ligand NameOpacity protein
SourceNeisseria meningitidis (Bacteria)
Sequence of ligandMNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF
Length273
TypeProtein
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorMannose-binding lectins
Type of receptorMannose receptor (MR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorB1PN75.fasta
Swiss prot IDB1PN75
Length Of Receptor38
FunctionMBL binding to N. meningitidis and increases complement activation and killing of organisms.
Assay usedELISA
PMID15004183
Year of Publication2004
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0207
Ligand NameOpacity protein
SourceNeisseria meningitidis (Bacteria)
Sequence of ligandMNPAPKNLLFSSLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYAAERITHDYPKATGANNTSTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASYRKWNNNKYSVNTKEVSRNNSNGNDTWQELKTENQENGSFHAVSSLGLSAIYDFKLNDKFDKFKPYIGARVAYGHVKHQVHSVRKETTTVFSKPSGSATKPGQIPSLVTKPAYHESHSISSLGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF
Length273
TypeProtein
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorMannose-binding lectins
Type of receptorMannose receptor (MR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorB1PN75.fasta
Swiss prot IDB1PN75
Length Of Receptor38
FunctionMBL binding to N. meningitidis and increases complement activation and killing of organisms.
Assay usedELISA
PMID15004183
Year of Publication2004
Pubchem assayPubchem Assay