Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_0780	PscI Click for more detail	Pseudomonas aeruginosa (Bacteria)	MDISRMGAQAQITSLEELSGGPAGAAHVAEFERAMGGAGSLGGDLLSELGQIRERFSQAKQELQMELSTPGDDPNSLMQMQWSLMRITMQEELIAKTVGRMSQNVETLMKTQ	112	Protein	Natural	It activates caspase-1 through NLRC4 and secrete IL-1Œ≤	Nod-like receptor C4 (NLRC4)	NOD-like receptor (NLR)	Mice	Bone marrow‚Äìderived macrophages	NA	Q3UP24.fasta	Q3UP24	1024	It leads to the clearance of the pathogen from the system	ELISA	20133635	2010	Pubchem Assay
PRRID_0780	PscI Click for more detail	Pseudomonas aeruginosa (Bacteria)	MDISRMGAQAQITSLEELSGGPAGAAHVAEFERAMGGAGSLGGDLLSELGQIRERFSQAKQELQMELSTPGDDPNSLMQMQWSLMRITMQEELIAKTVGRMSQNVETLMKTQ	112	Protein	Natural	It activates caspase-1 through NLRC4 and secrete IL-1Œ≤	Nod-like receptor C4 (NLRC4)	NOD-like receptor (NLR)	Mice	Bone marrow‚Äìderived macrophages	NA	Q3UP24.fasta	Q3UP24	1024	It leads to the clearance of the pathogen from the system	ELISA	20133635	2010	Pubchem Assay
PRRID_0781	R-Lipopolysaccharide (LPS) Click for more detail	Salmonella minnesota (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Activate monocytes and neutrophils with differential CD14 expression.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes and Neutrophils	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	NA	20721471	2010	Pubchem Assay
PRRID_0781	R-Lipopolysaccharide (LPS) Click for more detail	Salmonella minnesota (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Activate monocytes and neutrophils with differential CD14 expression.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes and Neutrophils	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	NA	20721471	2010	Pubchem Assay
PRRID_0787	S-Lipopolysaccharide (LPS) Click for more detail	Salmonella abortus equi (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Activate monocytes and neutrophils with differential CD14 expression.	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Monocytes and Neutrophils	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	NA	20721471	2010	Pubchem Assay
PRRID_0787	S-Lipopolysaccharide (LPS) Click for more detail	Salmonella abortus equi (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Activate monocytes and neutrophils with differential CD14 expression.	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Monocytes and Neutrophils	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	NA	20721471	2010	Pubchem Assay
PRRID_0788	SE-derived secreted factor (SE-S) Click for more detail	Staphylococcus epidermidis strain 1457 (Bacteria)	MNYSKITVTLIIILLCTFSFEFSFNRFVQADESRPKIESLKKKSELDSTALYNIKTSYSQDNIILDIKNKTNSTQLLSNDLIFDDITLKEWNKNSLKTEFNSSEIANHFKGKKVDIFGIYYGANCIGEVSKRTGCIYGGITLHEEEKIDQKNSIGVNVFKDGSQQKGFMITTDKKEPTIQELDLKTRKVIQNQYKIYNSETGNIQKGYMEFHSNSSSFYYDLFNFKGKYSVDFLKFYNDNKTINSSNLHIDVYLYSQ	257	Soluble factor	Natural	TLR2 mediated SE-induced cytokine production such as TNF, CXCL1 and CXCL2	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	human embryonic kidney cells, human whole blood and murine primary macrophages	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	TLR2 mediates recognition of live SE and clearance of SE bacteremia.	Cytokines assay	20404927	2010	Pubchem Assay
PRRID_0788	SE-derived secreted factor (SE-S) Click for more detail	Staphylococcus epidermidis strain 1457 (Bacteria)	MNYSKITVTLIIILLCTFSFEFSFNRFVQADESRPKIESLKKKSELDSTALYNIKTSYSQDNIILDIKNKTNSTQLLSNDLIFDDITLKEWNKNSLKTEFNSSEIANHFKGKKVDIFGIYYGANCIGEVSKRTGCIYGGITLHEEEKIDQKNSIGVNVFKDGSQQKGFMITTDKKEPTIQELDLKTRKVIQNQYKIYNSETGNIQKGYMEFHSNSSSFYYDLFNFKGKYSVDFLKFYNDNKTINSSNLHIDVYLYSQ	257	Soluble factor	Natural	TLR2 mediated SE-induced cytokine production such as TNF, CXCL1 and CXCL2	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	human embryonic kidney cells, human whole blood and murine primary macrophages	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	TLR2 mediates recognition of live SE and clearance of SE bacteremia.	Cytokines assay	20404927	2010	Pubchem Assay
PRRID_0789	SE-derived secreted factor (SE-S) Click for more detail	Staphylococcus epidermidis strain 1457 (Bacteria)	MNYSKITVTLIIILLCTFSFEFSFNRFVQADESRPKIESLKKKSELDSTALYNIKTSYSQDNIILDIKNKTNSTQLLSNDLIFDDITLKEWNKNSLKTEFNSSEIANHFKGKKVDIFGIYYGANCIGEVSKRTGCIYGGITLHEEEKIDQKNSIGVNVFKDGSQQKGFMITTDKKEPTIQELDLKTRKVIQNQYKIYNSETGNIQKGYMEFHSNSSSFYYDLFNFKGKYSVDFLKFYNDNKTINSSNLHIDVYLYSQ	257	Soluble factor	Natural	TLR2 mediated SE-induced cytokine production such as TNF, CXCL1 and CXCL2	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	human embryonic kidney cells, human whole blood and murine primary macrophages	Leucine-rich Repeat (LRR) Domain	Q99MB1.fasta	Q99MB1	905	TLR2 mediates recognition of live SE and clearance of SE bacteremia.	Cytokines assay	20404927	2010	Pubchem Assay
PRRID_0789	SE-derived secreted factor (SE-S) Click for more detail	Staphylococcus epidermidis strain 1457 (Bacteria)	MNYSKITVTLIIILLCTFSFEFSFNRFVQADESRPKIESLKKKSELDSTALYNIKTSYSQDNIILDIKNKTNSTQLLSNDLIFDDITLKEWNKNSLKTEFNSSEIANHFKGKKVDIFGIYYGANCIGEVSKRTGCIYGGITLHEEEKIDQKNSIGVNVFKDGSQQKGFMITTDKKEPTIQELDLKTRKVIQNQYKIYNSETGNIQKGYMEFHSNSSSFYYDLFNFKGKYSVDFLKFYNDNKTINSSNLHIDVYLYSQ	257	Soluble factor	Natural	TLR2 mediated SE-induced cytokine production such as TNF, CXCL1 and CXCL2	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	human embryonic kidney cells, human whole blood and murine primary macrophages	Leucine-rich Repeat (LRR) Domain	Q99MB1.fasta	Q99MB1	905	TLR2 mediates recognition of live SE and clearance of SE bacteremia.	Cytokines assay	20404927	2010	Pubchem Assay
PRRID_0802	SitC-His Click for more detail	S. aureus (Bacteria)	NA	NA	Lipoprotein	Natural	Induce IL-6 and TNF-‚ç∫ release	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Monocytes	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	20679445	2010	Pubchem Assay
PRRID_0802	SitC-His Click for more detail	S. aureus (Bacteria)	NA	NA	Lipoprotein	Natural	Induce IL-6 and TNF-‚ç∫ release	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Monocytes	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	20679445	2010	Pubchem Assay
PRRID_0803	SitC-His Click for more detail	S. aureus (Bacteria)	NA	NA	Lipoprotein	Natural	Activation of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	HEK293	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	20679445	2010	Pubchem Assay
PRRID_0803	SitC-His Click for more detail	S. aureus (Bacteria)	NA	NA	Lipoprotein	Natural	Activation of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	HEK293	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	20679445	2010	Pubchem Assay
PRRID_0804	SMP-105 Click for more detail	M. bovis BCG Tokyo 172 (Bacteria)	NA	NA	Cell-wall Skeleton	Natural	Binding of SMP-105 to TLR2 leads to the production of IL-12 p40 cytokines	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	C57BL/6J mice	BC-1 (Immature Dendritic cell line)	NA	Q9QUN7.fasta	Q9QUN7	784	It leads to the maturation and activation of BC-1.	ELISA	22491171	2010	Pubchem Assay
PRRID_0804	SMP-105 Click for more detail	M. bovis BCG Tokyo 172 (Bacteria)	NA	NA	Cell-wall Skeleton	Natural	Binding of SMP-105 to TLR2 leads to the production of IL-12 p40 cytokines	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	C57BL/6J mice	BC-1 (Immature Dendritic cell line)	NA	Q9QUN7.fasta	Q9QUN7	784	It leads to the maturation and activation of BC-1.	ELISA	22491171	2010	Pubchem Assay
PRRID_0817	Triacetylated lipoproteins Click for more detail	M. tuberculosis (Bacteria)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	On binding to the receptor it, activates the heterocomplex of TLR2/6 and secretion of cytokines takes place	Toll-like receptor 2/1 (TLR2/1)	Toll-like receptor (TLR)	DNA samples from peripheral blood of TB patients	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Immunostimulation and inflammation	NA	20797905	2010	NA
PRRID_0817	Triacetylated lipoproteins Click for more detail	M. tuberculosis (Bacteria)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	On binding to the receptor it, activates the heterocomplex of TLR2/6 and secretion of cytokines takes place	Toll-like receptor 2/1 (TLR2/1)	Toll-like receptor (TLR)	DNA samples from peripheral blood of TB patients	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Immunostimulation and inflammation	NA	20797905	2010	NA
PRRID_0818	Triacylated lipopeptides Click for more detail	Bacteria	NA	NA	Lipopeptides	Natural	Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins	Toll-like receptor 2 (TLR2)-Toll-like receptor (TLR1 dimer)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It coauses the inflammation	NA	20740341	2010	NA
PRRID_0818	Triacylated lipopeptides Click for more detail	Bacteria	NA	NA	Lipopeptides	Natural	Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins	Toll-like receptor 2 (TLR2)-Toll-like receptor (TLR1 dimer)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It coauses the inflammation	NA	20740341	2010	NA
PRRID_0819	Triacylated lipopeptides Click for more detail	Bacteria and Mycobacteria	NA	NA	Lipopeptides	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It leadsto the secretion of the proinfalmmatory cytokines	NA	20620129	2010	NA
PRRID_0819	Triacylated lipopeptides Click for more detail	Bacteria and Mycobacteria	NA	NA	Lipopeptides	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It leadsto the secretion of the proinfalmmatory cytokines	NA	20620129	2010	NA
PRRID_0820	Type A CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	The bindinginduces IFN-‚ç∫	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	plasmacytoid DCs	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It provides immunity against the bacterial infection	NA	20636030	2010	NA
PRRID_0820	Type A CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	The bindinginduces IFN-‚ç∫	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	plasmacytoid DCs	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It provides immunity against the bacterial infection	NA	20636030	2010	NA
PRRID_0821	Type B CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It activates macrophages and B-cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It promotes the enhancement of antibody production	NA	20636030	2010	NA
PRRID_0821	Type B CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It activates macrophages and B-cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It promotes the enhancement of antibody production	NA	20636030	2010	NA
PRRID_0822	Type C CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It induces IFN-‚ç∫ and activates macrophages and B-cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It promotes the enhancement of antibody production and provides immunity against bacterial infection	NA	20636030	2010	NA
PRRID_0822	Type C CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It induces IFN-‚ç∫ and activates macrophages and B-cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	NA	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It promotes the enhancement of antibody production and provides immunity against bacterial infection	NA	20636030	2010	NA
PRRID_0824	Unknown Click for more detail	P. syringae (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	It has role in disease resistance.	CERK1	Pattern recognition receptor (PRR)	Plants	NA	NA	A8R7E6.fasta	A8R7E6	617	It has role in disease resistance.	NA	20713980	2010	Pubchem Assay
PRRID_0824	Unknown Click for more detail	P. syringae (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	It has role in disease resistance.	CERK1	Pattern recognition receptor (PRR)	Plants	NA	NA	A8R7E6.fasta	A8R7E6	617	It has role in disease resistance.	NA	20713980	2010	Pubchem Assay
PRRID_0825	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Natural	It leads to the maturation, differentiation, and/or proliferation of NK cells, T cells, B cells, monocytes and macrophages and production of pro-inflammatory and Th-1 biased cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	B cells and pDC	NA	Q9NR96.fasta	Q9NR96	1032	It has the role in the inflammation.	NA	20713100	2010	Pubchem Assay
PRRID_0825	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Natural	It leads to the maturation, differentiation, and/or proliferation of NK cells, T cells, B cells, monocytes and macrophages and production of pro-inflammatory and Th-1 biased cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	B cells and pDC	NA	Q9NR96.fasta	Q9NR96	1032	It has the role in the inflammation.	NA	20713100	2010	Pubchem Assay
PRRID_0826	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Natural	It leads to the activation of the TLR9 and results into the secretion of the cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It has the role in the inflammation.	NA	20706677	2010	Pubchem Assay
PRRID_0826	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Natural	It leads to the activation of the TLR9 and results into the secretion of the cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It has the role in the inflammation.	NA	20706677	2010	Pubchem Assay
PRRID_0827	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It's binding does not induces the production of IL6, IL8, MMP3 and MMP4	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Fibroblast Like Synoviocytes (FLS)	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It has a role in the pathogenesis of juvenile idiopathic arthritis and cartilage destruction	ELISA	20571165	2010	Pubchem Assay
PRRID_0827	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It's binding does not induces the production of IL6, IL8, MMP3 and MMP4	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Fibroblast Like Synoviocytes (FLS)	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It has a role in the pathogenesis of juvenile idiopathic arthritis and cartilage destruction	ELISA	20571165	2010	Pubchem Assay
PRRID_0828	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	The binding leads to the activation of the NF-	chToll-like receptor 21 (TLR21)	Toll-like receptor (TLR)	Chicken	HD11 macrophage	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	Luciferase assay	20498358	2010	NA
PRRID_0828	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	The binding leads to the activation of the NF-	chToll-like receptor 21 (TLR21)	Toll-like receptor (TLR)	Chicken	HD11 macrophage	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It leads to the inflammatory response from the immune system leads to the clearance of pathogens	Luciferase assay	20498358	2010	NA
PRRID_0829	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It leads to increased expression of cytokine IL-12 p41	Toll-like receptor 21 (TLR2)	Toll-like receptor (TLR)	Chicken	Macrophage-like cell line (HD11)	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	This results into the inflammatory response.	NA	20471186	2010	NA
PRRID_0829	Unmethylated CpG DNA Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	It leads to increased expression of cytokine IL-12 p41	Toll-like receptor 21 (TLR2)	Toll-like receptor (TLR)	Chicken	Macrophage-like cell line (HD11)	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	This results into the inflammatory response.	NA	20471186	2010	NA
PRRID_0830	Uropathogenic E. coli Click for more detail	Bacteria	NA	NA	NA	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD94	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory and IFN-‚ç∫	NA	20620129	2010	Pubchem Assay
PRRID_0830	Uropathogenic E. coli Click for more detail	Bacteria	NA	NA	NA	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD94	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory and IFN-‚ç∫	NA	20620129	2010	Pubchem Assay
PRRID_0839	Virulence factor p60 Click for more detail	Listeriamonocytogenes (Bacteria)	MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE	529	Protein	Natural	It activates of nuclear factor kB (NF-kB) and induces proinflammatory cytokine production.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	Macropahes	LRR	Q9QUK6.fasta	Q9QUK6	835	It provides host resistance against infection with L. monocytogenes.	ELISA	20337701	2010	Pubchem Assay
PRRID_0839	Virulence factor p60 Click for more detail	Listeriamonocytogenes (Bacteria)	MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE	529	Protein	Natural	It activates of nuclear factor kB (NF-kB) and induces proinflammatory cytokine production.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	Macropahes	LRR	Q9QUK6.fasta	Q9QUK6	835	It provides host resistance against infection with L. monocytogenes.	ELISA	20337701	2010	Pubchem Assay
PRRID_0840	Virulence factor p60 Click for more detail	Listeriamonocytogenes (Bacteria)	MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE	529	Protein	Natural	It activates of nuclear factor kB (NF-kB) and induces proinflammatory cytokine production.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	Macrophage RAW264.7 cells	LRR	Q9QUK6.fasta	Q9QUK6	835	It provides host resistance against infection with L. monocytogenes.	ELISA	20337701	2010	Pubchem Assay
PRRID_0840	Virulence factor p60 Click for more detail	Listeriamonocytogenes (Bacteria)	MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE	529	Protein	Natural	It activates of nuclear factor kB (NF-kB) and induces proinflammatory cytokine production.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	Macrophage RAW264.7 cells	LRR	Q9QUK6.fasta	Q9QUK6	835	It provides host resistance against infection with L. monocytogenes.	ELISA	20337701	2010	Pubchem Assay
PRRID_0844	Whole bacteria Click for more detail	Legionella pneumophila (Bacteria)	NA	NA	Whole organism	Natural	It activates the p38 MAPK and JNK as well as recruitment of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Primary human small airway epithelial cells (SAEC)	LRR	O60603.fasta	O60603	784	hBD-2 elicits an antimicrobial effect on L. pneumophila.	ELISA	20154223	2010	Pubchem Assay
PRRID_0844	Whole bacteria Click for more detail	Legionella pneumophila (Bacteria)	NA	NA	Whole organism	Natural	It activates the p38 MAPK and JNK as well as recruitment of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Primary human small airway epithelial cells (SAEC)	LRR	O60603.fasta	O60603	784	hBD-2 elicits an antimicrobial effect on L. pneumophila.	ELISA	20154223	2010	Pubchem Assay
PRRID_0845	Whole bacteria Click for more detail	Legionella pneumophila (Bacteria)	NA	NA	Whole organism	Natural	It activates the p38 MAPK and JNK as well as recruitment of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Primary human small airway epithelial cells (SAEC)	LRR	O60603.fasta	O60603	784	hBD-2 elicits an antimicrobial effect on L. pneumophila.	ELISA	20154223	2010	Pubchem Assay
PRRID_0845	Whole bacteria Click for more detail	Legionella pneumophila (Bacteria)	NA	NA	Whole organism	Natural	It activates the p38 MAPK and JNK as well as recruitment of NF-	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Primary human small airway epithelial cells (SAEC)	LRR	O60603.fasta	O60603	784	hBD-2 elicits an antimicrobial effect on L. pneumophila.	ELISA	20154223	2010	Pubchem Assay
PRRID_0851	Zymosan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)O)O)O)O)O	NA	Glucan	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory cytokines	NA	20620129	2010	Pubchem Assay
PRRID_0851	Zymosan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)O)O)O)O)O	NA	Glucan	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory cytokines	NA	20620129	2010	Pubchem Assay
PRRID_0859	Œ≤ -1,3-glucan Click for more detail	Vibrio harveyi (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Glucan	Natural	NA	GNBP	Gram-negative Bacteria-binding Protein (GNBPs)	Artemia sinica	NA	NA	NA	NA	NA	Have cytoprotective effect	NA	20699104	2010	NA
PRRID_0859	Œ≤ -1,3-glucan Click for more detail	Vibrio harveyi (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Glucan	Natural	NA	GNBP	Gram-negative Bacteria-binding Protein (GNBPs)	Artemia sinica	NA	NA	NA	NA	NA	Have cytoprotective effect	NA	20699104	2010	NA
PRRID_0860	Œ≤ -1,3-glucan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Carbohydrate	Natural	Œ≤-glucan binds to the LGBP and induce innate immunity	Lipopolysaccharide and b-1, 3-glucan binding protein (LGBP)	Pattern recognition receptor (PRR)	Chlamys farreri	Hemocytes, gills and mantle	NA	NA	NA	NA	It is involved in pathogens recognition and bacterial agglutination.	NA	20659562	2010	NA
PRRID_0860	Œ≤ -1,3-glucan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Carbohydrate	Natural	Œ≤-glucan binds to the LGBP and induce innate immunity	Lipopolysaccharide and b-1, 3-glucan binding protein (LGBP)	Pattern recognition receptor (PRR)	Chlamys farreri	Hemocytes, gills and mantle	NA	NA	NA	NA	It is involved in pathogens recognition and bacterial agglutination.	NA	20659562	2010	NA
PRRID_0870	Atypic lipopolysaccharides Click for more detail	Leptospira interrogans (Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0870	Atypic lipopolysaccharides Click for more detail	Leptospira interrogans (Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0877	Diacylated Lipopeptide Click for more detail	Mycoplasma (Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 6 (TLR6)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0877	Diacylated Lipopeptide Click for more detail	Mycoplasma (Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 6 (TLR6)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0886	Fimbriae H protein (FimH) Click for more detail	Uropathogenic E.coli (Bacteria)	MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ	300	Protein	Natural	stimulate the innate immune system and elicits protective responses against bacterial and viral infections	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	C57BL/6 mice	NA	NA	Q9QUK6.fasta	Q9QUK6	835	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21945041	2011	Pubchem Assay
PRRID_0886	Fimbriae H protein (FimH) Click for more detail	Uropathogenic E.coli (Bacteria)	MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ	300	Protein	Natural	stimulate the innate immune system and elicits protective responses against bacterial and viral infections	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	C57BL/6 mice	NA	NA	Q9QUK6.fasta	Q9QUK6	835	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21945041	2011	Pubchem Assay
PRRID_0887	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Myeloid cells, epithelial cells, microglia, astrocytes	NA	O60602.fasta	O60602	858	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21982558	2011	Pubchem Assay
PRRID_0887	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Myeloid cells, epithelial cells, microglia, astrocytes	NA	O60602.fasta	O60602	858	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21982558	2011	Pubchem Assay
PRRID_0888	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21955443	2011	NA
PRRID_0888	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21955443	2011	NA
PRRID_0889	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21949866	2011	NA
PRRID_0889	Flagellin Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	triggers immune responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21949866	2011	NA
PRRID_0890	Flagellin Click for more detail	S. typhimurium (Bacteria)	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	elicits innate responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Human colon adenocarcinoma intestinal epithelial cells	amino (N) and carboxyl (C) domains (D) of the flagellin protein (ND1/2ECHCD2/1)	O60602.fasta	O60602	858	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21949773	2011	Pubchem Assay
PRRID_0890	Flagellin Click for more detail	S. typhimurium (Bacteria)	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Protein	Natural	elicits innate responses	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	Human colon adenocarcinoma intestinal epithelial cells	amino (N) and carboxyl (C) domains (D) of the flagellin protein (ND1/2ECHCD2/1)	O60602.fasta	O60602	858	It stimulates the production of proinflammatory cytokines, such as TNF-Œ±, through signaling via the adaptor protein MyD88.	NA	21949773	2011	Pubchem Assay
PRRID_0911	iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail	Bacteria	N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O	NA	Pattern-associated molecular patterns (PAMPs)	Natural	peptidoglycan substructures	Nucleotide Binding Oligomerization Domain Containing 1 (Nod1)	NOD-like receptor (NLR)	Human	Eosinophils	NA	Q9Y239.fasta	Q9Y239	953	play key roles in regulation of¬†innate immune response. NLRs can cooperate with¬†Toll-like receptors¬†and regulate inflammatory and apoptotic response.	real-time reverse transcription-PCR, FACS, ELISA	21978001	2011	Pubchem Assay
PRRID_0911	iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail	Bacteria	N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O	NA	Pattern-associated molecular patterns (PAMPs)	Natural	peptidoglycan substructures	Nucleotide Binding Oligomerization Domain Containing 1 (Nod1)	NOD-like receptor (NLR)	Human	Eosinophils	NA	Q9Y239.fasta	Q9Y239	953	play key roles in regulation of¬†innate immune response. NLRs can cooperate with¬†Toll-like receptors¬†and regulate inflammatory and apoptotic response.	real-time reverse transcription-PCR, FACS, ELISA	21978001	2011	Pubchem Assay
PRRID_0916	lipo-arabinomannan Click for more detail	Mycobacteria (Bacteria)	CCC(CO)NCCNC(CC)CO	NA	Glycolipid	Natural	serve as a modulin with immunoregulatory and anti-inflammatory effects.¬†	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21982558	2011	Pubchem Assay
PRRID_0916	lipo-arabinomannan Click for more detail	Mycobacteria (Bacteria)	CCC(CO)NCCNC(CC)CO	NA	Glycolipid	Natural	serve as a modulin with immunoregulatory and anti-inflammatory effects.¬†	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21982558	2011	Pubchem Assay
PRRID_0917	lipo-arabinomannan Click for more detail	Mycobacteria (Bacteria)	CCC(CO)NCCNC(CC)CO	NA	Glycolipid	Natural	serve as a modulin with immunoregulatory and anti-inflammatory effects.¬†	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0917	lipo-arabinomannan Click for more detail	Mycobacteria (Bacteria)	CCC(CO)NCCNC(CC)CO	NA	Glycolipid	Natural	serve as a modulin with immunoregulatory and anti-inflammatory effects.¬†	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0923	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	elicit innate immune response	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21949866	2011	NA
PRRID_0923	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	elicit innate immune response	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21949866	2011	NA
PRRID_0926	Lipoproteins/lipopeptides Click for more detail	Bacteria	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21982558	2011	Pubchem Assay
PRRID_0926	Lipoproteins/lipopeptides Click for more detail	Bacteria	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21982558	2011	Pubchem Assay
PRRID_0927	Lipoproteins/lipopeptides Click for more detail	Different bacterial pathogens(Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21955443	2011	NA
PRRID_0927	Lipoproteins/lipopeptides Click for more detail	Different bacterial pathogens(Bacteria)	NA	NA	Lipid	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21955443	2011	NA
PRRID_0928	Lipoteichoic Acid (LTA) Click for more detail	Bacteria	C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O	NA	Amphiphile	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0928	Lipoteichoic Acid (LTA) Click for more detail	Bacteria	C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O	NA	Amphiphile	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0936	monophosphoryl lipid A (MPL) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC	NA	Lipid	Natural	triggers immune responses	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Balb/c mice	Spleen and lung	NA	P58681.fasta	P58681	1050	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	ELISA	21963872	2011	Pubchem Assay
PRRID_0936	monophosphoryl lipid A (MPL) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC	NA	Lipid	Natural	triggers immune responses	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Balb/c mice	Spleen and lung	NA	P58681.fasta	P58681	1050	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	ELISA	21963872	2011	Pubchem Assay
PRRID_0940	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	LPS was also shown to play a role in alloimmune lung injury	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Intracellular TIR domains	O00206.fasta	O00206	839	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21959264	2011	Pubchem Assay
PRRID_0940	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	LPS was also shown to play a role in alloimmune lung injury	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Intracellular TIR domains	O00206.fasta	O00206	839	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21959264	2011	Pubchem Assay
PRRID_0941	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	LPS was also shown to play a role in alloimmune lung injury	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Drosophila melanogaster	NA	Intracellular TIR domains	NA	NA	NA	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21959264	2011	NA
PRRID_0941	Lipopolysaccharide (LPS) Click for more detail	Gram negative Bacteria (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	LPS was also shown to play a role in alloimmune lung injury	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Drosophila melanogaster	NA	Intracellular TIR domains	NA	NA	NA	TLR 4 leads to an intracellular signaling pathway¬†NF-Œ∫B and inflammatory cytokine production which is responsible for activating the innate immune system	NA	21959264	2011	NA
PRRID_0945	Pam3CSK4 Click for more detail	Bacteria	CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O	NA	Lipoprotein	Synthetic	Mimics the acylated amino terminus of bacterial LPs and is a potent activator of the proinflammatory transcription factor NF-Œ∫B.	Toll-like receptor (TLR1/Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	intracellular TIR domains	NA	NA	NA	TLR2 is involved in the specific recognition of a wide range of ligands, either as a homodimer or as a heterodimer with TLR1 or TLR6	NA	21959264	2011	NA
PRRID_0945	Pam3CSK4 Click for more detail	Bacteria	CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O	NA	Lipoprotein	Synthetic	Mimics the acylated amino terminus of bacterial LPs and is a potent activator of the proinflammatory transcription factor NF-Œ∫B.	Toll-like receptor (TLR1/Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	intracellular TIR domains	NA	NA	NA	TLR2 is involved in the specific recognition of a wide range of ligands, either as a homodimer or as a heterodimer with TLR1 or TLR6	NA	21959264	2011	NA
PRRID_0946	Peptidoglycan (PGN) Click for more detail	Bacteria	CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N	NA	Peptidoglycan	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0946	Peptidoglycan (PGN) Click for more detail	Bacteria	CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N	NA	Peptidoglycan	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons	NA	O60603.fasta	O60603	784	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0948	phenol-soluble modulin Click for more detail	S. aureus (Bacteria)	MEFVAKLFKFFKDLLGKFLGNN	22	Protein	Natural	triggers immune responses	Toll-like receptor 6 (TLR6)	Toll-like receptor (TLR)	Human	Myeloid cells, dendritic cells, microglia, astrocytes	NA	Q9Y2C9.fasta	Q9Y2C9	796	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0948	phenol-soluble modulin Click for more detail	S. aureus (Bacteria)	MEFVAKLFKFFKDLLGKFLGNN	22	Protein	Natural	triggers immune responses	Toll-like receptor 6 (TLR6)	Toll-like receptor (TLR)	Human	Myeloid cells, dendritic cells, microglia, astrocytes	NA	Q9Y2C9.fasta	Q9Y2C9	796	significant role in the pathogenesis of severe inflammatory responses	NA	21982558	2011	Pubchem Assay
PRRID_0949	phenol-soluble modulin Click for more detail	Staphylococcus epidermidis (Bacteria)	MEFVAKLFKFFKDLLGKFLGNN	22	Protein	Natural	triggers immune responses	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21955443	2011	NA
PRRID_0949	phenol-soluble modulin Click for more detail	Staphylococcus epidermidis (Bacteria)	MEFVAKLFKFFKDLLGKFLGNN	22	Protein	Natural	triggers immune responses	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	plays a fundamental role in¬†pathogen¬†recognition and activation of¬†innate immunity	NA	21955443	2011	NA
PRRID_0954	Porins Click for more detail	Neisseria meningitidis (Bacteria)	MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF	396	Pattern-associated molecular patterns (PAMPs)	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA
PRRID_0954	Porins Click for more detail	Neisseria meningitidis (Bacteria)	MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF	396	Pattern-associated molecular patterns (PAMPs)	Natural	elicit innate immune response	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	significant role in the pathogenesis of severe inflammatory responses	NA	21955443	2011	NA

previous 1 2 3 4 567 8 9...35 36 next