Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0936 details
Primary information
PRRIDPRRID_0936
Ligand Namemonophosphoryl lipid A (MPL)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
LengthNA
TypeLipid
OccurenceNatural
Role of Ligandtriggers immune responses
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Balb/c mice
LocalizationSpleen and lung
DomainNA
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID21963872
Year of Publication2011
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0936
Ligand Namemonophosphoryl lipid A (MPL)
SourceGram negative Bacteria (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
LengthNA
TypeLipid
OccurenceNatural
Role of Ligandtriggers immune responses
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Balb/c mice
LocalizationSpleen and lung
DomainNA
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
Functionplays a fundamental role in pathogen recognition and activation of innate immunity
Assay usedELISA
PMID21963872
Year of Publication2011
Pubchem assayPubchem Assay