Detailed description page of PRRDB2.0

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PRRID_0887 details
Primary information
PRRIDPRRID_0887
Ligand NameFlagellin
SourceBacteria
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of Ligandtriggers immune responses
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMyeloid cells, epithelial cells, microglia, astrocytes
DomainNA
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedNA
PMID21982558
Year of Publication2011
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0887
Ligand NameFlagellin
SourceBacteria
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of Ligandtriggers immune responses
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMyeloid cells, epithelial cells, microglia, astrocytes
DomainNA
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedNA
PMID21982558
Year of Publication2011
Pubchem assayPubchem Assay