Detailed description page of PRRDB2.0

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PRRID_0890 details
Primary information
PRRIDPRRID_0890
Ligand NameFlagellin
SourceS. typhimurium (Bacteria)
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of Ligandelicits innate responses
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHuman colon adenocarcinoma intestinal epithelial cells
Domainamino (N) and carboxyl (C) domains (D) of the flagellin protein (ND1/2ECHCD2/1)
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedNA
PMID21949773
Year of Publication2011
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0890
Ligand NameFlagellin
SourceS. typhimurium (Bacteria)
Sequence of ligandMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Length495
TypeProtein
OccurenceNatural
Role of Ligandelicits innate responses
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHuman colon adenocarcinoma intestinal epithelial cells
Domainamino (N) and carboxyl (C) domains (D) of the flagellin protein (ND1/2ECHCD2/1)
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.
Assay usedNA
PMID21949773
Year of Publication2011
Pubchem assayPubchem Assay