Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0033 | Acetylated LDL Click for more detail | NA | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated LDL is a potent ligand for MARCO | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0033 | Acetylated LDL Click for more detail | NA | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated LDL is a potent ligand for MARCO | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0048 | Apoptotic thymocytes Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation. | Scavenger receptor class A | Scavenger receptor (SR) | Mice | Thymic macrophages | NA | Q68EF1.fasta | Q68EF1 | 474 | SR-A may play a role in the clearance of dying cells in the thymus. | Phagocytosis Assay | 8901603 | 1996 | Pubchem Assay |
| PRRID_0048 | Apoptotic thymocytes Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation. | Scavenger receptor class A | Scavenger receptor (SR) | Mice | Thymic macrophages | NA | Q68EF1.fasta | Q68EF1 | 474 | SR-A may play a role in the clearance of dying cells in the thymus. | Phagocytosis Assay | 8901603 | 1996 | Pubchem Assay |
| PRRID_0057 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0057 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0059 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0059 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0064 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0064 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0065 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | AcLDL pretreatment increased expression of macrosialin | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0065 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | AcLDL pretreatment increased expression of macrosialin | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0070 | Minimally oxidized LDL (MM-LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0070 | Minimally oxidized LDL (MM-LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0071 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | OxLDL pretreatment increased expression of macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0071 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | OxLDL pretreatment increased expression of macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0081 | CpG DNA Click for more detail | Bacteria | NA | NA | Nucleic Acid | Natural | elicit innate immune response | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | NA | Q9NR96.fasta | Q9NR96 | 1032 | induce type I interferons (IFN) and other cytokines production. | NA | 11130078 | 2000 | Pubchem Assay |
| PRRID_0081 | CpG DNA Click for more detail | Bacteria | NA | NA | Nucleic Acid | Natural | elicit innate immune response | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | NA | Q9NR96.fasta | Q9NR96 | 1032 | induce type I interferons (IFN) and other cytokines production. | NA | 11130078 | 2000 | Pubchem Assay |
| PRRID_0082 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Raw 264.7 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0082 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Raw 264.7 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0090 | Not Determined Click for more detail | herpes simplex virus (virus) | NA | NA | Others | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUN7.fasta | Q9QUN7 | 784 | NA | NA | 11062499 | 2000 | Pubchem Assay |
| PRRID_0090 | Not Determined Click for more detail | herpes simplex virus (virus) | NA | NA | Others | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUN7.fasta | Q9QUN7 | 784 | NA | NA | 11062499 | 2000 | Pubchem Assay |
| PRRID_0096 | viral hemagglutinin (HA) Click for more detail | Influenza A (virus) | MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI | 566 | NA | Natural | Immunostimulant | NA | NA | Mice (Murine) | Macrophages | NA | NA | NA | NA | NA | ELISA | 0 | 2000 | NA |
| PRRID_0096 | viral hemagglutinin (HA) Click for more detail | Influenza A (virus) | MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI | 566 | NA | Natural | Immunostimulant | NA | NA | Mice (Murine) | Macrophages | NA | NA | NA | NA | NA | ELISA | 0 | 2000 | NA |
| PRRID_0100 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | NA | tandem mass spectrometry | 0 | 2001 | Pubchem Assay |
| PRRID_0100 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Immunostimulant | Toll-like receptor 5 (TLR5) | Toll-like receptor (TLR) | Mice | NA | NA | Q9JLF7.fasta | Q9JLF7 | 859 | NA | tandem mass spectrometry | 0 | 2001 | Pubchem Assay |
| PRRID_0116 | Fragments of heparan sulphate Click for more detail | Host (Endogenous) (others) | COC1C(C(C(OC1C(=O)[O-])OC2C(OC(C(C2[O-])NOS(=O)(=O)O)OC)COS(=O)(=O)O)OS(=O)(=O)O)O | NA | Proteoglycan | Natural | Heparan sulfate induces nuclear translocation of NF-kappaB. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | Bone-Marrow culture | NA | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 plays the role in the activation and maturation of dendritic cells, thus suggesting that vertebrate TLR monitor perturbations to the well-being of tissues. | EMSA | 11994480 | 2002 | Pubchem Assay |
| PRRID_0116 | Fragments of heparan sulphate Click for more detail | Host (Endogenous) (others) | COC1C(C(C(OC1C(=O)[O-])OC2C(OC(C(C2[O-])NOS(=O)(=O)O)OC)COS(=O)(=O)O)OS(=O)(=O)O)O | NA | Proteoglycan | Natural | Heparan sulfate induces nuclear translocation of NF-kappaB. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | Bone-Marrow culture | NA | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 plays the role in the activation and maturation of dendritic cells, thus suggesting that vertebrate TLR monitor perturbations to the well-being of tissues. | EMSA | 11994480 | 2002 | Pubchem Assay |
| PRRID_0129 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | 5MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0129 | Heat-shock proteins 60 Click for more detail | Chlamydia pneumoniae(Bacteria) | 5MAAKNIKYNEEARKKIHKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEIELEDKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYSEGLRNVTAGANPMDLKRGIDKAVKVVVDELKKISKPVQHHKEIAQVATISANNDSEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDVVEGMNFNRGYLSSYFSTNPETQECVLEDALILIYDKKISGIKDFLPVLQQVAESGRPLLIIAEEIEGEALATLVVNRLRAGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLVSEELGMKLENTTLAMLGKAKKVIVTKEDTTIVEGLGNKPDIQARCDNIKKQIEDSTSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALVRCIPTLEAFLPMLANEDEAIGTRIILKALTAPLKQIASNAGKEGAIICQQVLARSANEGYDALRDAYTDMIDAGILDPTKVTRSALESAASIAGLLLTTEALIADIPEEKSSSAPAMPSAGMDY | 544 | Protein | Natural | Chlamydial Heat Shock Protein 60 Activates NF-kappaB through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macrophages | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | This leads to the inflammatory response. | NF- | 11801686 | 2002 | Pubchem Assay |
| PRRID_0130 | Hemagglutinin Click for more detail | virus (measles virus) | MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLGRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKRSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYLEQPVSNDLSNCMVALGELKLAALCHGEDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDNRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPYLFNVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMEGMGVSCTVTREDGTNRR | 617 | Glycoprotein | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | NA | NA | Q9QUN7.fasta | Q9QUN7 | 784 | NA | ELISA | 12163593 | 2002 | Pubchem Assay |
| PRRID_0130 | Hemagglutinin Click for more detail | virus (measles virus) | MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLGRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKRSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYLEQPVSNDLSNCMVALGELKLAALCHGEDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDNRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPYLFNVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMEGMGVSCTVTREDGTNRR | 617 | Glycoprotein | Natural | Immunostimulant | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | NA | NA | Q9QUN7.fasta | Q9QUN7 | 784 | NA | ELISA | 12163593 | 2002 | Pubchem Assay |
| PRRID_0131 | Hyaluronic acid Click for more detail | Host (Endogenous) (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Carbohydrate | Natural | potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Bone Marrow–derived DCs | transmembrane domain that associates with the intra- cellular adaptor protein MyD88 | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 11781369 | 2002 | Pubchem Assay |
| PRRID_0131 | Hyaluronic acid Click for more detail | Host (Endogenous) (others) | CC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O | NA | Carbohydrate | Natural | potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Bone Marrow–derived DCs | transmembrane domain that associates with the intra- cellular adaptor protein MyD88 | Q9QUK6.fasta | Q9QUK6 | 835 | TLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system | ELISA | 11781369 | 2002 | Pubchem Assay |
| PRRID_0132 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Lectin-like oxidized LDLreceptor 1 | C type Lectin (CTL/CLR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q9EQ09.fasta | Q9EQ09 | 363 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0132 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Lectin-like oxidized LDLreceptor 1 | C type Lectin (CTL/CLR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q9EQ09.fasta | Q9EQ09 | 363 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0133 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Scavenger receptor class B, type I (SR-BI) | Scavenger receptor (SR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q06BI8.fasta | Q06BI8 | 494 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0133 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Scavenger receptor class B, type I (SR-BI) | Scavenger receptor (SR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q06BI8.fasta | Q06BI8 | 494 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0142 | Neisserial porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | It leads to the induction of NF-kappaB nuclear translocation. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | It has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2. | NF-kB luciferase reporter assay | 11823477 | 2002 | Pubchem Assay |
| PRRID_0142 | Neisserial porins Click for more detail | Neisseria meningitidis (Bacteria) | MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKNTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSARSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF | 396 | Protein | Natural | It leads to the induction of NF-kappaB nuclear translocation. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | It has the role in immunopotentiating activity, such as by stimulate B cells and up-regulate the surface expression of B7-2. | NF-kB luciferase reporter assay | 11823477 | 2002 | Pubchem Assay |
| PRRID_0148 | 7-allyl-8-oxo-G (loxoribine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0148 | 7-allyl-8-oxo-G (loxoribine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0149 | 7-allyl-8-oxo-G (loxoribine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0149 | 7-allyl-8-oxo-G (loxoribine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0151 | 7-deazadG Click for more detail | Guanosine (others) | C1C(C(OC1N2C=CC3=C2NC(=NC3=O)N)CO)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0151 | 7-deazadG Click for more detail | Guanosine (others) | C1C(C(OC1N2C=CC3=C2NC(=NC3=O)N)CO)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0152 | 7-deazadG Click for more detail | Guanosine (others) | C1C(C(OC1N2C=CC3=C2NC(=NC3=O)N)CO)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0152 | 7-deazadG Click for more detail | Guanosine (others) | C1C(C(OC1N2C=CC3=C2NC(=NC3=O)N)CO)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0154 | 7-deazaguanosine (7-deazaG) Click for more detail | Guanosine (others) | C1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0154 | 7-deazaguanosine (7-deazaG) Click for more detail | Guanosine (others) | C1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0155 | 7-deazaguanosine (7-deazaG) Click for more detail | Guanosine (others) | C1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0155 | 7-deazaguanosine (7-deazaG) Click for more detail | Guanosine (others) | C1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0157 | 7-Thia-8-oxoguanosine (TOG) Click for more detail | Guanosine (others) | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0157 | 7-Thia-8-oxoguanosine (TOG) Click for more detail | Guanosine (others) | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0158 | 7-Thia-8-oxoguanosine (TOG) Click for more detail | Guanosine (others) | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0158 | 7-Thia-8-oxoguanosine (TOG) Click for more detail | Guanosine (others) | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0160 | 9-hexyl-guanine Click for more detail | Guanosine (others) | CCN1C=NC2=C1NC(=NC2=O)N | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0160 | 9-hexyl-guanine Click for more detail | Guanosine (others) | CCN1C=NC2=C1NC(=NC2=O)N | NA | Nucleic Acid | Synthetic | It induces the production of IL-6, IL-12, type I and II IFNs. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0161 | 9-hexyl-guanine Click for more detail | Guanosine (others) | CCN1C=NC2=C1NC(=NC2=O)N | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0161 | 9-hexyl-guanine Click for more detail | Guanosine (others) | CCN1C=NC2=C1NC(=NC2=O)N | NA | Nucleic Acid | Synthetic | It induces the production of IL-6 and IL-12. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Bone-Marrow derived macrophages | LRR | P58681.fasta | P58681 | 1050 | It leads to the immunostimulatory by immune system. | ELISA | 12738885 | 2003 | Pubchem Assay |
| PRRID_0163 | C12-iE-DAP Click for more detail | Chemical derivative of iE-DAP(others) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Synthetic | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0163 | C12-iE-DAP Click for more detail | Chemical derivative of iE-DAP(others) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Synthetic | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0173 | iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail | Bacteria | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0173 | iE-DAP (gamma-D-glutamyl-meso diaminopimelic acid) Click for more detail | Bacteria | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Peptide | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice (Murine) | Macrophages | NA | Q8BHB0.fasta | Q8BHB0 | 953 | mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan. | ELISA | 12796777 | 2003 | Pubchem Assay |
| PRRID_0177 | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | Loxoribine (7-allyl-7,8- dihydro-8-oxo-guanosine) activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | NA | P58681.fasta | P58681 | 1050 | It leads to the endosomal maturation. | ELISA | 14579267 | 2003 | Pubchem Assay |
| PRRID_0177 | Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) Click for more detail | Guanosine (others) | C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O | NA | Nucleic Acid | Synthetic | Loxoribine (7-allyl-7,8- dihydro-8-oxo-guanosine) activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | Spleenocytes | NA | P58681.fasta | P58681 | 1050 | It leads to the endosomal maturation. | ELISA | 14579267 | 2003 | Pubchem Assay |
| PRRID_0182 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0182 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0183 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0183 | PIM2 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0184 | PIM6 Click for more detail | Mycobacterium bovis Bacillus Calmette Guerin (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0184 | PIM6 Click for more detail | Mycobacterium bovis Bacillus Calmette Guerin (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0185 | PIM6 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0185 | PIM6 Click for more detail | Mtb H37Rv (Bacteria) | NA | NA | Carbohydrate | Natural | It stimulates the stimulate TNF-alpha, which leads to IL-12 p40 secretion. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Primary Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response. | ELISA | 12775723 | 2003 | Pubchem Assay |
| PRRID_0186 | Resiquimod (R-848) Click for more detail | imidazoquinoline (others) | CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N | NA | Nucleic Acid | Synthetic | Resisuimod activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production. | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Mice | Spleenocytes | NA | P58682.fasta | P58682 | 1032 | It leads to the endosomal maturation. | ELISA | 14579267 | 2003 | Pubchem Assay |
| PRRID_0186 | Resiquimod (R-848) Click for more detail | imidazoquinoline (others) | CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N | NA | Nucleic Acid | Synthetic | Resisuimod activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production. | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Mice | Spleenocytes | NA | P58682.fasta | P58682 | 1032 | It leads to the endosomal maturation. | ELISA | 14579267 | 2003 | Pubchem Assay |
| PRRID_0192 | Advillin Click for more detail | Host (Endogenous) (others) | MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF | 819 | Protein | Natural | It induces neurite-like outgrowth. | Scavenger receptor expressed by endothelial cells 1 (SREC-I) | Scavenger receptor (SR) | Mice (Murine) | Fibroblastic L cells | Cytoplasmic domain | Q5ND28.fasta | Q5ND28 | 820 | SREC-I lead to changes in cell morphology. | NA | 15247299 | 2004 | Pubchem Assay |
| PRRID_0192 | Advillin Click for more detail | Host (Endogenous) (others) | MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF | 819 | Protein | Natural | It induces neurite-like outgrowth. | Scavenger receptor expressed by endothelial cells 1 (SREC-I) | Scavenger receptor (SR) | Mice (Murine) | Fibroblastic L cells | Cytoplasmic domain | Q5ND28.fasta | Q5ND28 | 820 | SREC-I lead to changes in cell morphology. | NA | 15247299 | 2004 | Pubchem Assay |
| PRRID_0197 | Envelope protein Click for more detail | virus (Mouse Mammary Tumor Virus) | NA | NA | Protein | Natural | activation of the NF-κB pro-inflammatory cascade | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 14694089 | 2004 | Pubchem Assay |
| PRRID_0197 | Envelope protein Click for more detail | virus (Mouse Mammary Tumor Virus) | NA | NA | Protein | Natural | activation of the NF-κB pro-inflammatory cascade | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 14694089 | 2004 | Pubchem Assay |
| PRRID_0198 | glucuronoxylomannan Click for more detail | Cryptococcus neoformans(fungi) | NA | NA | Carbohydrate | Natural | It leads to the induction of tumor necrosis factor alpha, interleukin-4, IL-10, IL-12p70 and gamma interferon. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Lung | NA | Q9QUK6.fasta | Q9QUK6 | 835 | It leads to the inflammatory response against the fungi Cryptococcus neoformans. | ELISA | 15322035 | 2004 | Pubchem Assay |
| PRRID_0198 | glucuronoxylomannan Click for more detail | Cryptococcus neoformans(fungi) | NA | NA | Carbohydrate | Natural | It leads to the induction of tumor necrosis factor alpha, interleukin-4, IL-10, IL-12p70 and gamma interferon. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Lung | NA | Q9QUK6.fasta | Q9QUK6 | 835 | It leads to the inflammatory response against the fungi Cryptococcus neoformans. | ELISA | 15322035 | 2004 | Pubchem Assay |
| PRRID_0199 | glucuronoxylomannan Click for more detail | Cryptococcus neoformans(fungi) | NA | NA | Carbohydrate | Natural | It leads to the induction of tumor necrosis factor alpha, interleukin-4, IL-10, IL-12p70 and gamma interferon. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Lung | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response against the fungi Cryptococcus neoformans. | ELISA | 15322035 | 2004 | Pubchem Assay |
| PRRID_0199 | glucuronoxylomannan Click for more detail | Cryptococcus neoformans(fungi) | NA | NA | Carbohydrate | Natural | It leads to the induction of tumor necrosis factor alpha, interleukin-4, IL-10, IL-12p70 and gamma interferon. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Lung | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It leads to the inflammatory response against the fungi Cryptococcus neoformans. | ELISA | 15322035 | 2004 | Pubchem Assay |
| PRRID_0210 | serum amyloid A Click for more detail | Host (Endogenous) (others) | MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY | 122 | Protein | Natural | Serum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding. | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | Mice | Hepatocytes | NA | Q61009.fasta | Q61009 | 509 | SR-BI plays a key role in SAA metabolism through its ability to interact with and internalize SAA and, moreover, SAA influences HDL cholesterol metabolism through its inhibitory effects on SR-BI-mediated selective lipid. uptake | NA | 15561721 | 2004 | Pubchem Assay |
| PRRID_0210 | serum amyloid A Click for more detail | Host (Endogenous) (others) | MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY | 122 | Protein | Natural | Serum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding. | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | Mice | Hepatocytes | NA | Q61009.fasta | Q61009 | 509 | SR-BI plays a key role in SAA metabolism through its ability to interact with and internalize SAA and, moreover, SAA influences HDL cholesterol metabolism through its inhibitory effects on SR-BI-mediated selective lipid. uptake | NA | 15561721 | 2004 | Pubchem Assay |
| PRRID_0222 | Hemozoin Click for more detail | protozoa (Plasmodium falciparum) (others) | CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.[Fe+5].[Fe+5].[Fe+5].[Fe+5] | NA | Others | Natural | immunostimulant | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | Toll/interleukin 1 receptor domain | Q9NR96.fasta | Q9NR96 | 1032 | abrogated HZ-induced cytokine production | NA | 15630134 | 2005 | Pubchem Assay |
| PRRID_0222 | Hemozoin Click for more detail | protozoa (Plasmodium falciparum) (others) | CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.[Fe+5].[Fe+5].[Fe+5].[Fe+5] | NA | Others | Natural | immunostimulant | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Mice | NA | Toll/interleukin 1 receptor domain | Q9NR96.fasta | Q9NR96 | 1032 | abrogated HZ-induced cytokine production | NA | 15630134 | 2005 | Pubchem Assay |
| PRRID_0223 | Microparticles containingOVAand poly-U Click for more detail | NA | NA | NA | Nucleic Acid | Synthetic | ssRNA can act as a potent adjuvant and modulator of adaptive immunological responses, which leads to the enhanced production of TNF-alpha and IL-12p40. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | BMDCs | NA | P58681.fasta | P58681 | 1050 | It stimulates proinflammatory and antiviral responses. | ELISA | 16278038 | 2005 | Pubchem Assay |
| PRRID_0223 | Microparticles containingOVAand poly-U Click for more detail | NA | NA | NA | Nucleic Acid | Synthetic | ssRNA can act as a potent adjuvant and modulator of adaptive immunological responses, which leads to the enhanced production of TNF-alpha and IL-12p40. | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Mice | BMDCs | NA | P58681.fasta | P58681 | 1050 | It stimulates proinflammatory and antiviral responses. | ELISA | 16278038 | 2005 | Pubchem Assay |
| PRRID_0224 | Microparticles containingOVAand poly-U Click for more detail | NA | NA | NA | Nucleic Acid | Synthetic | ssRNA can act as a potent adjuvant and modulator of adaptive immunological responses, which leads to the enhanced production of TNF-alpha and IL-12p40. | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Mice | BMDCs | NA | P58682.fasta | P58682 | 1032 | It stimulates proinflammatory and antiviral responses. | ELISA | 16278038 | 2005 | Pubchem Assay |
| PRRID_0224 | Microparticles containingOVAand poly-U Click for more detail | NA | NA | NA | Nucleic Acid | Synthetic | ssRNA can act as a potent adjuvant and modulator of adaptive immunological responses, which leads to the enhanced production of TNF-alpha and IL-12p40. | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Mice | BMDCs | NA | P58682.fasta | P58682 | 1032 | It stimulates proinflammatory and antiviral responses. | ELISA | 16278038 | 2005 | Pubchem Assay |
| PRRID_0225 | muramyl tetrapeptide Click for more detail | muramyl dipeptide derivative (others) | NA | NA | Peptide | Synthetic | Immunostimulant | Nucleotide-binding oligomerization domain protein 1 | NOD-like receptor (NLR) | Mice (Murine) | NA | NA | Q8BHB0.fasta | Q8BHB0 | 953 | NA | ELISA | 16211083 | 2005 | Pubchem Assay |
| PRRID_0225 | muramyl tetrapeptide Click for more detail | muramyl dipeptide derivative (others) | NA | NA | Peptide | Synthetic | Immunostimulant | Nucleotide-binding oligomerization domain protein 1 | NOD-like receptor (NLR) | Mice (Murine) | NA | NA | Q8BHB0.fasta | Q8BHB0 | 953 | NA | ELISA | 16211083 | 2005 | Pubchem Assay |
| PRRID_0228 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |
| PRRID_0228 | Seeligeriolysin O ((rLSO483) Click for more detail | Listeria seeligeri (Bacteria) | MKIFGLVIMSLLFVSLPITQQPEARDVPAYDRSEVTISPAETPESPPATPKTPVEKKHAEEINKYIWGLNYDKNSILVYQGEAVTNVPPKKGYKDGSEYIVVEKKKKGINQNNADISVINAISSLTYPGALVKANRELVENQPNVLPVKRDSLTLSVDLPGMTKKDNKIFVKNPTKSNVNNAVNTLVERWNDKYSKAYPNINAKIDYSDEMAYSESQLIAKFGTAFKAVNNSLNVNFEAISDGKVQEEVISFKQIYYNINVNEPTSPSKFFGGSVTKEQLDALGVNAENPPAYISSVAYGRQVYVKLSSSSHSNKVKTAFEAAMSGKSVKGDVELTNIIKNSSFKAVIYGGSAKEEVEIIDGNLGELRDILKKGSTYDRENPGVPISYTTNFLKDNDLAVVKNNSEYIETTSKSYTDGKINIDHSGGYVAQFNISWDEVSYDENGNEIKVHKKWGENYKSKLAHFTSSIYLPGNARNINIYARECTGLFWEWWRTVIDDRNLPLVKNRNVSIWGTTLYPRHSNNVDNPIQ | 530 | Protein | Natural | It induces TNF-alpha production and NF-kappaB activation, which leads to the production of IL-12 p40 and IL-12 p70. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | NA | Q9QUN7.fasta | Q9QUN7 | 784 | This leads to the inflammatory response. | Transfection and nuclear factor j-B reporter assay | 16291660 | 2005 | Pubchem Assay |