Detailed description page of PRRDB2.0

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PRRID_0210 details
Primary information
PRRIDPRRID_0210
Ligand Nameserum amyloid A
SourceHost (Endogenous) (others)
Sequence of ligandMKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
Length122
TypeProtein
OccurenceNatural
Role of LigandSerum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding.
Name of receptorScavenger receptor B-1 (SR-B1)
Type of receptorScavenger receptor (SR)
Source Mice
LocalizationHepatocytes
DomainNA
Sequence of Receptor Q61009.fasta
Swiss prot ID Q61009
Length Of Receptor509
FunctionSR-BI plays a key role in SAA metabolism through its ability to interact with and internalize SAA and, moreover, SAA influences HDL cholesterol metabolism through its inhibitory effects on SR-BI-mediated selective lipid. uptake
Assay usedNA
PMID15561721
Year of Publication2004
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0210
Ligand Nameserum amyloid A
SourceHost (Endogenous) (others)
Sequence of ligandMKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
Length122
TypeProtein
OccurenceNatural
Role of LigandSerum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding.
Name of receptorScavenger receptor B-1 (SR-B1)
Type of receptorScavenger receptor (SR)
Source Mice
LocalizationHepatocytes
DomainNA
Sequence of Receptor Q61009.fasta
Swiss prot ID Q61009
Length Of Receptor509
FunctionSR-BI plays a key role in SAA metabolism through its ability to interact with and internalize SAA and, moreover, SAA influences HDL cholesterol metabolism through its inhibitory effects on SR-BI-mediated selective lipid. uptake
Assay usedNA
PMID15561721
Year of Publication2004
Pubchem assayPubchem Assay