Detailed description page of PRRDB2.0

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PRRID_0154 details
Primary information
PRRIDPRRID_0154
Ligand Name7-deazaguanosine (7-deazaG)
SourceGuanosine (others)
Sequence of ligandC1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt induces the production of IL-6, IL-12, type I and II IFNs.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainLRR
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
FunctionIt leads to the immunostimulatory by immune system.
Assay usedELISA
PMID12738885
Year of Publication2003
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0154
Ligand Name7-deazaguanosine (7-deazaG)
SourceGuanosine (others)
Sequence of ligandC1=CN(C2=C1C(=O)N=C(N2)N)C3C(C(C(O3)CO)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt induces the production of IL-6, IL-12, type I and II IFNs.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainLRR
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
FunctionIt leads to the immunostimulatory by immune system.
Assay usedELISA
PMID12738885
Year of Publication2003
Pubchem assayPubchem Assay