Detailed description page of PRRDB2.0

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PRRID_0186 details
Primary information
PRRIDPRRID_0186
Ligand NameResiquimod (R-848)
Sourceimidazoquinoline (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandResisuimod activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production.
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainNA
Sequence of ReceptorP58682.fasta
Swiss prot IDP58682
Length Of Receptor1032
FunctionIt leads to the endosomal maturation.
Assay usedELISA
PMID14579267
Year of Publication2003
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0186
Ligand NameResiquimod (R-848)
Sourceimidazoquinoline (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandResisuimod activates the MyD88-dependent TLR/IL-1R signaling pathway and induces the cytokine production.
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationSpleenocytes
DomainNA
Sequence of ReceptorP58682.fasta
Swiss prot IDP58682
Length Of Receptor1032
FunctionIt leads to the endosomal maturation.
Assay usedELISA
PMID14579267
Year of Publication2003
Pubchem assayPubchem Assay