| Primary information |
|---|
| PRRID | PRRID_0157 |
| Ligand Name | 7-Thia-8-oxoguanosine (TOG) |
| Source | Guanosine (others) |
| Sequence of ligand | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | It induces the production of IL-6, IL-12, type I and II IFNs. |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Spleenocytes |
| Domain | LRR |
| Sequence of Receptor | P58681.fasta |
| Swiss prot ID | P58681 |
| Length Of Receptor | 1050 |
| Function | It leads to the immunostimulatory by immune system. |
| Assay used | ELISA |
| PMID | 12738885 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0157 |
| Ligand Name | 7-Thia-8-oxoguanosine (TOG) |
| Source | Guanosine (others) |
| Sequence of ligand | C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)SC2=O)O)O)O |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | It induces the production of IL-6, IL-12, type I and II IFNs. |
| Name of receptor | Toll-like receptor 7 (TLR7) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Spleenocytes |
| Domain | LRR |
| Sequence of Receptor | P58681.fasta |
| Swiss prot ID | P58681 |
| Length Of Receptor | 1050 |
| Function | It leads to the immunostimulatory by immune system. |
| Assay used | ELISA |
| PMID | 12738885 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |