Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID1020 | SequenceACSSSPSKHCG | NameTDN | Nature of peptide or cargoTD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | AssayConfocal Laser Scanning Microscopy | Tissue permeabilitySignificant permeability of the peptide can be seen in confocal images | Tissue SampleMale SD rats skin cells | PUBMED ID23391375 |
| ID1104 | SequenceKWLNALLHHGLNCAK GVLA | NameHG1 | Nature of peptide or cargoAntimicrobial | AssayConfocal microscopy, HPLC | Tissue permeabilitySignificant permeability of the peptide can be seen in confocal images | Tissue SampleICR mice skin | PUBMED ID21220538 |
| ID1117 | SequencepGlu-HWSYwLRPG | NameTriptorelin | Nature of peptide or cargoLuteinizing hormone releasing hormone (LHRH) superagonist | AssayFranz diffusion cell, HPLC | Tissue permeability64.9±8.8% degraded | Tissue SampleInterior skin surface of dermatomed skin (DS) of porcine | PUBMED ID19486932 |
| ID1118 | SequencepGlu-HWSYwLRPG | NameTriptorelin | Nature of peptide or cargoLuteinizing hormone releasing hormone (LHRH) superagonist | AssayFranz diffusion cell, HPLC | Tissue permeability15±4.1% degraded | Tissue SampleInterior skin surface of heat separated epidermis (HSE) of porcine | PUBMED ID19486932 |
| ID1119 | SequencepGlu-HWSYwLRPG | NameTriptorelin | Nature of peptide or cargoLuteinizing hormone releasing hormone (LHRH) superagonist | AssayFranz diffusion cell, HPLC | Tissue permeability100% degraded | Tissue SampleInterior skin surface of full thickness skin (FTS) of porcine | PUBMED ID19486932 |
| ID1120 | SequencepGlu-HWSYwLRPG | NameTriptorelin | Nature of peptide or cargoLuteinizing hormone releasing hormone (LHRH) superagonist | AssayFranz diffusion cell, HPLC | Tissue permeability87.8±4.4% degraded | Tissue SampleInterior skin surface of dermatomed skin (DS) of porcine | PUBMED ID19486932 |
| ID1121 | SequencepGlu-HWSYwLRPG | NameTriptorelin | Nature of peptide or cargoLuteinizing hormone releasing hormone (LHRH) superagonist | AssayFranz diffusion cell, HPLC | Tissue permeability51.3±6% degraded | Tissue SampleInterior skin surface of heat separated epidermis (HSE) of porcine | PUBMED ID19486932 |
| ID1131 | SequenceLIGR | NameLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayVybrant Phagocytosis Assay | Tissue permeabilitySignificant increase in the LIGR-induced keratinocyte phagocytosis observed using Vybrant Phagocytosis Assay | Tissue SampleHaCaT keratinocytes | PUBMED ID18426410 |
| ID1132 | SequenceLIGR | NameLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of mice skin sections | Tissue SampleDorsum skin of SKH-1 hairless female mice | PUBMED ID18426410 |
| ID1133 | SequenceLIGR | NameLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of swine skin sections | Tissue SampleDorsum skin of pigmented yucatan microswine | PUBMED ID18426410 |
| ID1134 | SequenceLIGR | NameLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of Human skin section skin sections | Tissue SampleHuman skin samples grafted onto SCID mice | PUBMED ID18426410 |
| ID1135 | SequenceSLIGR | NameSLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayVybrant Phagocytosis Assay | Tissue permeabilitySignificant increase in the LIGR-induced keratinocyte phagocytosis observed using Vybrant Phagocytosis Assay | Tissue SampleHaCaT keratinocytes | PUBMED ID18426410 |
| ID1136 | SequenceSLIGR | NameSLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of mice skin sections | Tissue SampleDorsum skin of SKH-1 hairless female mice | PUBMED ID18426410 |
| ID1137 | SequenceSLIGR | NameSLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of swine skin sections | Tissue SampleDorsum skin of pigmented yucatan microswine | PUBMED ID18426410 |
| ID1138 | SequenceSLIGR | NameSLIGR | Nature of peptide or cargoActivation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | AssayFontana-Mason (F&M) stain | Tissue permeabilityThe increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of Human skin section skin sections | Tissue SampleHuman skin samples grafted onto SCID mice | PUBMED ID18426410 |
| ID1143 | Sequencer–nle–nle–nle–r–nle–nle–nle–g–y | NameRDP58 | Nature of peptide or cargoImmunomodulator | AssayHistological assay using bright field microscopy | Tissue permeabilityIt can be clearly seen from the histological images that topical application of RDP58results in significant decrease in tthe hickness of the ear skin as compared to control (TPA applied ear skin) | Tissue SampleEar of mice | PUBMED ID16117788 |
| ID1194 | SequenceMpr-YFQNCPrG | NameDesmopressin | Nature of peptide or cargoIt is a peptide hormone that is used chiefly for treatment of enuresis | AssayRadioimmunoassay | Tissue permeability10 ng/ml serum conc. of desmopressin after ~100 min of coated microneedle array application | Tissue SampleLateral skin areas of the thorax of hairless guinea pigs | PUBMED ID15212882 |
| ID1195 | SequenceMpr-YFQNCPrG | NameDesmopressin | Nature of peptide or cargoIt is a peptide hormone that is used chiefly for treatment of enuresis | AssayRadioimmunoassay | Tissue permeability1 ng/ml serum conc. of desmopressin after ~250 min of coated microneedle array application | Tissue SampleLateral skin areas of the thorax of hairless guinea pigs | PUBMED ID15212882 |
| ID1196 | SequenceMpr-YFQNCPrG | NameDesmopressin | Nature of peptide or cargoIt is a peptide hormone that is used chiefly for treatment of enuresis | AssayRadioimmunoassay | Tissue permeability0.8 ng/ml serum conc. of desmopressin after ~350 min of coated microneedle array application | Tissue SampleLateral skin areas of the thorax of hairless guinea pigs | PUBMED ID15212882 |
| ID1199 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 2.37 ± 0.94 µg h−1 cm−2 at 100% DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1200 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 9.87 ± 4.91 µg h−1 cm−2 at 75% pulsed DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1201 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 5.57 ± 2.27 µg h−1 cm−2 at 50% pulsed DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1202 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 1.21 ± 0.76 µg h−1 cm−2 at 75%+/25%− AC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1203 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 0.006 ± 0.004 µg h−1 cm−2 at 50%+/50%− AC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1204 | SequencepGlu-HWSY-D-2-Nal-LRPG | NameNafarelin | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityNafarelin flux= 1.99 ± 2.04 µg h−1 cm−2 at 100% DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1205 | SequencepGlu-HWSY-D-2-Nal-LRPG | NameNafarelin | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityNafarelin flux= 6.47 ± 0.87 µg h−1 cm−2 at 75% DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1206 | SequencepGlu-HWSY-D-2-Nal-LRPG | NameNafarelin | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityNafarelin flux= 0.96 ± 0.79 µg h−1 cm−2 at 50% pulsed DC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1207 | SequencepGlu-HWSY-D-2-Nal-LRPG | NameNafarelin | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityNafarelin flux= 3.33 ± 1.04 µg h−1 cm−2 at 75%+/25%- AC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1208 | SequencepGlu-HWSY-D-2-Nal-LRPG | NameNafarelin | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityNafarelin flux= 0.15 ± 0.09 µg h−1 cm−2 at 50%+/50%- AC | Tissue SampleHuman cadaver skin | PUBMED ID14757511 |
| ID1209 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 12.39 ± 5.32 µg h−1 cm−2 at 75% pulsed DC (500 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1210 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 5.97 ± 3.20 µg h−1 cm−2 at 50% pulsed DC (500 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1211 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux=9.07 ± 4.28 µg h−1 cm−2 at 25% pulsed DC (500 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1212 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 8.70±3.56 µg h−1 cm−2 at 75% pulsed DC (5 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1213 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 7.31±1.94 µg h−1 cm−2 at 50% pulsed DC (5 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1214 | SequencepGlu-HWSYGLRPG | NameLHRH | Nature of peptide or cargoPeptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | AssayHPLC | Tissue permeabilityLHRH flux= 9.35±1.98 µg h−1 cm−2 at 25% pulsed DC (5 Hz) | Tissue SampleEpidermis of human cadaver skin | PUBMED ID14757511 |
| ID1229 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.1 ± 0.7, Basal skin blood flow(PU)-378 ± 47, Heart rate(min-1)-424 ± 26, Respiratory rate(min-1)-113 ± 8, pH-7.38 ± 0.02, pCO2(kPa)-7.07 ± 0.37 and pO2(kPa)-7.91 ± 0.25 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1230 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.8 ± 1.0, Basal skin blood flow(PU)-421 ± 4, Heart rate(min-1)-417 ± 23, Respiratory rate(min-1)-118 ± 6, pH-7.39 ± 0.01, pCO2(kPa)-6.82 ± 0.27 and pO2(kPa)-8.43 ± 0.24 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1231 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.5 ± 1.0, Basal skin blood flow(PU)-454 ± 23, Heart rate(min-1)-423 ± 23, Respiratory rate(min-1)-123 ± 6, pH-7.40 ± 0.02, pCO2(pKa)-6.46 ± 0.31 and pO2(pKa)-9.87 ± 1.49 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1232 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.5 ± 0.8, Basal skin blood flow(PU)-348 ± 62, Heart rate(min-1)-419 ± 26, Respiratory rate(min-1)-115 ± 7, pH-7.37 ± 0.02, pCO2(pKa)-7.05 ± 0.56 and pO2(pKa)-7.39 ± 0.33 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1233 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.3 ± 0.7, Basal skin blood flow(PU)-370 ± 55, Heart rate(min-1)-329 ± 12, Respiratory rate(min-1)-89 ± 5, pH-7.33 ± 0.01, pCO2(pKa)-8.31 ± 0.25 and pO2(pKa)-9.24 ± 1.03 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1234 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.9 ± 0.8, Basal skin blood flow(PU)-358 ± 47, Heart rate(min-1)-349 ± 15, Respiratory rate(min-1)-101 ± 5, pH-7.33 ± 0.01, pCO2(pKa)-7.85 ± 0.23 and pO2(pKa)-9.30 ± 0.71 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1235 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.0 ± 0.5, Basal skin blood flow(PU)-287 ± 51, Heart rate(min-1)-353 ± 14, Respiratory rate(min-1)-98 ± 4, pH-7.33 ± 0.01, pCO2(pKa)-7.72 ± 0.34 and pO2(pKa)-8.43 ± 0.63 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1236 | SequencepGlu-HP | NameThyrotropin-releasing hormone (TRH) | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-8.2 ± 0.4, Basal skin blood flow(PU)-244 ± 50, Heart rate(min-1)-359 ± 11, Respiratory rate(min-1)-91 ± 9, pH-7.35 ± 0.02, pCO2(pKa)-6.89 ± 0.33 and pO2(pKa)-10.8 ± 1.55 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1237 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.2 ± 0.2, Basal skin blood flow(PU)-380 ± 44, Heart rate(min-1)-387 ± 18, Respiratory rate(min-1)-105 ± 10, pH-7.36 ± 0.03, pCO2(pKa)-7.42 ± 0.49 and pO2(pKa)-8.32 ± 0.70 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1238 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.5 ± 0.5, Basal skin blood flow(PU)-305 ± 72, Heart rate(min-1)-385 ± 3, Respiratory rate(min-1)-113 ± 5, pH-7.39 ± 0.01, pCO2(pKa)-6.72 ± 0.08 and pO2(pKa)-7.99 ± 0.60 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1239 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.1 ± 0.5, Basal skin blood flow(PU)-259 ± 69, Heart rate(min-1)-378 ± 4, Respiratory rate(min-1)-110 ± 8, pH-7.41 ± 0.01, pCO2(pKa)-6.51 ± 0.04 and pO2(pKa)-8.44 ± 0.46 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1240 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.9 ± 0.8, Basal skin blood flow(PU)-202 ± 71, Heart rate(min-1)-372 ± 17, Respiratory rate(min-1)-101 ± 4, pH-7.40 ± 0.01, pCO2(pKa)-6.58 ± 0.20 and pO2(pKa)-8.73 ± 0.60 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1241 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.0 ± 0.31, Basal skin blood flow(PU)-382 ± 32, Heart rate(min-1)-400 ± 8, Respiratory rate(min-1)-116 ± 7, pH-7.35 ± 0.01, pCO2(pKa)-7.73 ± 0.24 and pO2(pKa)-9.59 ± 1.04 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1242 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.7 ± 0.31, Basal skin blood flow(PU)-294 ± 42, Heart rate(min-1)-404 ± 10, Respiratory rate(min-1)-116 ± 7, pH-7.36 ± 0.01, pCO2(pKa)-7.14 ± 0.22 and pO2(pKa)-8.57 ± 0.31 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |
| ID1243 | SequencepGlu-3-methyl-HP | NameM-TRH | Nature of peptide or cargoTRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | AssayCardiovascular parameters and blood gas values determined by collecting blood at different time intervals | Tissue permeabilityOn application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.3 ± 0.33, Basal skin blood flow(PU)-213 ± 48, Heart rate(min-1)-407 ± 13, Respiratory rate(min-1)-107 ± 9, pH-7.38 ± 0.01, pCO2(pKa)-6.62 ± 0.24 and pO2(pKa)-10.6 ± 1.13 | Tissue SampleStratum corneum of the abdominal area of male Sprague-Dawley rats | PUBMED ID11179600 |