| PRIMARY INFORMATION |
|---|
| ID | 1195 |
| PMID | 15212882 |
| Year | 2004 |
| Sequence | Mpr-YFQNCPrG |
| Name | Desmopressin |
| Length | 8 |
| N-Terminal Modification | Mpr=3-Mercaptopropiony |
| C-Terminal Modification | Amidation |
| Linear/ Cyclic | Cyclic (Disulfide Bridge Mpr1-Cys6) |
| Chirality | Mix |
| Chemical Modification | None |
| Origin of Peptide | Synthetic |
| Nature of Peptide/Cargo | It is a peptide hormone that is used chiefly for treatment of enuresis |
| Mechanism | Not mentioned |
| Cargo Sequence/Structure | None |
Name of cargo
| Not applicable |
| Assay | Radioimmunoassay |
| Enhancer | Microneedle arrays |
| Properties of enhancer | Microneedles disrupt the stratum corneum |
| Concentration | Microneedle arrays were coated with 82 µg desmopressin |
| Incubation time | Patch application time was 15 min. |
| Tissue permeability (value with units) | 1 ng/ml serum conc. of desmopressin after ~250 min of coated microneedle array application |
| Tissue Sample | Lateral skin areas of the thorax of hairless guinea pigs |
| Ex vivo/In vivo/In vitro | in vivo |
| SECONDARY INFORMATION |
|---|
| STRUCTURE | |
| SMILES | N.A. |
