A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1098 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Calcimar | N.A. | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
1100 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Miacalcin | Novartis | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
1142 | Th1020 | Asparaginase | QMSLQQELRYIEALSAIVET Full view | 255 | Ic | Cancer | Elspar | Merck & Co. Inc | Lyophilized plug or powder | Intravenous or Intramuscular. Intravenous method dose has higher risk of allergic reaction, so often a test dose is given first. | Antineoplastic Agents | L-asparagine |
1145 | Th1021 | Thyrotropin Alfa | Alpha chain:APDVQDC< Full view | 204 | IV | Cancer | Thyrogen | Genzyme Inc | Lyophilized powder | Intramuscular preferably the buttocks | Diagnostic Agents | Thyrotropin receptor |
1216 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Repronex | N.A. | Sterile, lyophilized form | Subcutaneous or Intramuscular Injection. | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
1252 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | GlucaGen | Novo Nordisk | Sterile, lyophilized white powder | Subcutaneous, Intramuscular, or Intravenous infusion | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1253 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | Glucagon | Eli Lilly | Powder | Subcutaneously or Intramuscularly Injection | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1261 | Th1037 | Botulinum Toxin Type B | MPVTINNFNYNDPIDNNNII Full view | 255 | Ic | Neurological Disorder | Neurobloc | Solstice Neurosciences | Clear and colourless to light yellow solution | Intramuscular Injection | Antidystonic Agents | Vesicle-associated membrane protein 2,Vesicle-associated membrane protein 1,Synaptotagmin-2 |
1337 | Th1048 | Pegaspargase | MEFFKKTALAALVMGFSGAA Full view | 255 | Ic | Cancer | Oncaspar | Enzon Inc | Solution | Intravenous or Intramuscular administration | Antineoplastic Agents | L-asparagine |
1341 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Avonex | Biogen Inc | Lyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector. | Intramuscular Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1372 | Th1055 | Follitropin beta | A Chain: APDVQDCPECT Full view | 204 | Ib | Hormonal disorders | Follistim AQ | Merck | Sterile aqueous solution | Subcutaneous or Intramuscular administration | Fertility Agents | Follicle-stimulating hormone receptor |
1375 | Th1056 | Vasopressin | CYFQNCPRG Full view | 9 | Ib | Hormonal | Pitressin | JHP Pharmaceuticals | Sterile, aqueous solution of synthetic vasopressin | Intramuscular or Subcutaneous use | Antidiuretic Agents | Vasopressin V2 receptor,Vasopressin V1a receptor,Vasopressin V1b receptor |
1419 | Th1070 | Botulinum Toxin Type A | MPFVNKQFNYKDPVNGVDIA Full view | 1296 | Ic | Neurological Disorder | BOTOX | Allergan | Sterile, vacuum-dried purified botulinum toxin type A, produced from fermentation of Hall strainClostridium botulinum type A | Intramuscular, intradetrusor and intradermal use | Neuromuscular Blocking Agents, Anti-Wrinkle Agents and Antidystonic Agents | Growth hormone receptor |
1420 | Th1070 | Botulinum Toxin Type A | MPFVNKQFNYKDPVNGVDIA Full view | 1296 | Ic | Neurological Disorder | Dysport | Ipsen Pharmaceuticals | Sterile vial for reconstitution | Intramuscular Injection | Neuromuscular Blocking Agents, Anti-Wrinkle Agents and Antidystonic Agents | Growth hormone receptor |
1421 | Th1070 | Botulinum Toxin Type A | MPFVNKQFNYKDPVNGVDIA Full view | 1296 | Ic | Neurological Disorder | Xeomin | MERZ AESTHETICS | Sterile white to off-white lyophilized powder after reconstitution with preservative-free 0.9% Saline for Injection. | Intramuscular Injection | Neuromuscular Blocking Agents, Anti-Wrinkle Agents and Antidystonic Agents | Growth hormone receptor |
1439 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | BRAVELLE | Ferring Pharmaceuticals Inc. | Sterile, lyophilized powder used after reconstitution with sterile 0.9% Sodium Chloride Injection | Intramuscular and Subcutaneous administration | Fertility Agents | Glutamate carboxypeptidase 2 |
1440 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | Metrodin | N.A. | Sterile, lypholized form contains an acidic, water soluble glycoprotein biologically standardized for FSH gonadotropin activity | Intramuscular injection. | Fertility Agents | Glutamate carboxypeptidase 2 |
1456 | Th1086 | Interferon Alfa-2B, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | INTRON® A | Merck | Powder or solution | Intramuscular, Subcutaneous, Intralesional, or Intravenous injection | Immunosuppressive Agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin |
1465 | Th1089 | Palivizumab | VH region: QVTLRESG< Full view | 120 | IIIa | Infectious | Synagis | MedImmune | Sterile, preservative-free liquid solution | Intramuscular injection | Antiviral Agents | N.A. |
1500 | Th1103 | Cosyntropin | ACTH(1-24): SYSM Full view | 24 | IV | Hormonal | Cortrosyn | Amphastar Pharmaceuticals | N.A. | Intravenous injection, Intravenous infusion, Intramuscular injection | Hormones and Diagnostic Agents | Adrenocorticotropic hormone receptor |
1533 | Th1112 | Natural Alpha Interferon Or Multiferon | Inteferon alpha-1: Full view | 997 | IIa | Cancer/Infectious | Intron/ Roferon-A | N.A. | N.A. | Subcutaneous injection, Intravenous injection, Intramuscular injection | N.A. | N.A. |
1536 | Th1115 | Teicoplanin | N.A. Full view | 0 | IIa | Infectious | Targocid | NPS Pharmaceuticals | Light yellow solid | Intravenous injection, Intramuscular injection | Anti-Bacterial Agents | D-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycan |
1621 | Th1134 | Asparaginase Erwinia Chrysanthemi | ADKLPNIVILATGGTIAGSA Full view | 327 | Ic | Hormonal | Erwinaze | EUSA Pharma | Sterile, lyophilized, white powder in vials. | Intramuscular injection | Enzymes | N.A. |
1657 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | Protropin | Genentech Inc. | Sterile, white, lyophilized powder | Intramuscular or subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
1661 | Th1153 | Alefacept | Heavy Chain: CFSQQIY Full view | 705 | IIa | Immunological | Amevive | Astellas Pharma Inc. | Sterile, white-to-off-white, preservative-free, lyophilized powder | Intramuscular Injection | Dermatologic and Immunosupressive agents | T-cell surface antigen CD2, Complement C1r subcomponent, Complement C1q subcomponent subunit A, B, C, Low affinity immunoglobulin gamma Fc region receptor III-A,III-B, II-a, II-b, II-c |
1662 | Th1154 | OspA lipoprotein | MKKYLLGIGLILALIACKQN Full view | 272 | IIIa | Infectious | Lymerix | SmithKline Beecham | Sterile suspension | Intramuscular Injection | Vaccines | Toll-like receptor 2 |
1664 | Th1156 | Abarelix | N.A. Full view | 0 | IIIc | Hormonal | Plenaxis | Speciality european pharma | White to off-white sterile dry powder | Intramuscular Injection | Anti-Testosterone Agents | Gonadotropin-releasing hormone receptor |
1758 | Th1183 | Hepatitis B immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Hepagam B | Cangene Bio Pharma Inc. | Injection, Solution | Intramuscular; Intravenous | NA | HBsAg |
1762 | Th1183 | Hepatitis B immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Hyperhep B S/d | GRIFOLS USA, LLC | Injection | Intramuscular | NA | HBsAg |
1763 | Th1183 | Hepatitis B immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Nabi-HB | Biotest Pharmaceuticals Corporation | Injection | Intramuscular | NA | HBsAg |
1767 | Th1185 | Human clostridium tetani toxoid immune globulin | NA Full view | 0 | IIIb | Infectious Disease | Hypertet S/d | GRIFOLS USA, LLC | Injection | Intramuscular | NA | NA |
1768 | Th1186 | Human rabies virus immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Hyperab Rabies Immune Globulin Human | Cutter Med & Biol, Division Of Miles Canada Ltd. | Liquid | Intramuscular | NA | NA |
1769 | Th1186 | Human rabies virus immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Hyperrab S/d | Grifols Therapeutics Inc | Solution | Intramuscular | NA | NA |
1770 | Th1186 | Human rabies virus immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Imogam Rabies Inj 150unit/ml | Pasteur mÉrieux Serums Et Vaccins, s.a. | Clear, pale yellow to light brown liquid | Intramuscular | NA | NA |
1771 | Th1186 | Human rabies virus immune globulin | NA Full view | 0 | IIIa | Infectious Disease | Imogam Rabies Pasteurized | Sanofi Pasteur Limited | Solution | Intramuscular | NA | NA |
1772 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Hyp Rho D Inj 16.5% | Cutter Med & Biol, Division Of Miles Canada Ltd. | liquid | Intramuscular | NA | NA |
1773 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Hyperrho S/d Full Dose | GRIFOLS USA, LLC | Soution | Intramuscular | NA | NA |
1774 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Hyperrho S/d Mini-dose | GRIFOLS USA, LLC | Solution | Intramuscular | NA | NA |
1775 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Micrhogam Ultra-filtered Plus | Kedrion Melville, Inc. | Injection, Solution | Intramuscular | NA | NA |
1776 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Rhogam Ultra-filtered Plus | Kedrion Melville, Inc. | Injection, Solution | Intramuscular | NA | NA |
1777 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Rhophylac | Csl Behring Ag | Solution | Intramuscular; Intravenous | NA | NA |
1778 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Winrho Sdf | Aptevo Biotherapeutics Llc | kit | Intramuscular; Intravenous | NA | NA |
1779 | Th1187 | Human Rho(D) immune globulin | NA Full view | 0 | IIIb | Immunological Disorders | Winrho Sdf (liquid Formulation) | Aptevo Biotherapeutics Llc | liquid | Intramuscular; Intravenous | NA | NA |
1793 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Gamastan | Cutter Med & Biol, Division Of Miles Canada Ltd. | liquid | Intramuscular | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1794 | Th1190 | Immune Globulin Human | IGG1: PSALTQPPSASGSL Full view | 1338 | IIIb | Immunological Disorders | Gamastan S/d | GRIFOLS USA, LLC | Injection | Intramuscular | Immunologic Factors; Immunosuppressive Agents; Anti-Infective Agents | High affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor IB; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; Complement C3; Complement C4-A; Complement C4-B; Complement C5. |
1834 | Th1223 | Chorionic Gonadotropin (Human) | Alpha Chain: APDVQDC Full view | 237 | Ia | Hormonal Disorders | Pregnyl | Physicians Total Care, Inc. | Injection, Solution | Intramuscular, Subcutaneous | Hormones | Lutropin-choriogonadotropic hormone receptor |
1840 | Th1229 | Hepatitis A Vaccine | NA Full view | 0 | IIIa | Infectious Disease | Avaxim | Sanofi Pasteur Limited | Suspension | Intramuscular | Vaccine | NA |
1841 | Th1229 | Hepatitis A Vaccine | NA Full view | 0 | IIIa | Infectious Disease | Havrix | Dispensing Solutions, Inc. | Suspension | Intramuscular | Vaccine | NA |
1842 | Th1230 | Human Varicella-Zoster Immune Globulin | NA Full view | 0 | IIIa | Infectious Disease | VARIZIG | NA | lyophilized powder for solution | Intramuscular | Antibody | varicella zoster virus |