Shannon Entropy of Physico-chemical Properties for protein or peptide sequnces

 

This module has been developed to calculate Shannon Entropy based on Physico-chemical Properties for protein or peptide sequence(s), where users are allowed to paste or upload file with multiple protein/peptide sequences [fasta format or single line sequnces] similar to the Example sequence. The user can also provide the PDB or UniProt IDs in the mentioned format. For more information see HELP page.

Paste peptide sequence(s) in single line format or FASTA format:
OR Submit sequence file: 
OR PDB IDs:      
OR UniProt IDs: 
  • Select portion of Sequence:
    • This section allow users to select either complete or specific portion of the seqeunce, such as

      1. Whole: Performs operation on complete sequence
      2. N-Term: This allows to cut the user specified portion from N-terminal of the sequence
      3. C-Term: This allows to cut the user specified portion from C-terminal of the sequence
      4. Split: This allows users to split the sequence into fragments and performs calculation indepedently
      5. Rest: This allows users to drop the residues from N- and C-terminal and performs calculation on the remaining fragment
Whole   N-Term      C-Term     Split     Rest:  N-Term   C-Term  

Select desired Physico-chemical Properties:
This allows users to select and calculates the shannon entropy of particular physicochemical properties in a sequence
                                       
 Positively charged    Negatively charged    Neutral charged  
 Polarity    Non polarity    Aliphaticity  
 Cyclic    Aromaticity    Acidicity  
 Basicity    Neutral (ph)    Hydrophobicity  
 Hydrophilicity     Neutral     Hydroxylic   
 Sulphur content     Tiny     Small   
 Large