Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 136
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1129OSK-1 (alpha-KTx3.7) (Venom peptide)GVIINVKCKISRQCLEPCKKAGMRFGKCMNGKCHCTPK38LNoneNoneNoneLinearNaturalOrthochirus scrobiculosus (scorpion)K+ channelPotassium channel blockerBothNANAC57/BL6 miceNA10 mg/kgNA243331932014
1132Vm24AAAISCVGSPECPPKCRAQGCKNGKCMNRKCKCYYC36LNoneNoneNoneLinearNaturalVaejovis mexicanus smithi (scorpion)Kv1.3 channelsInhibits Kv1.3 channelsBothCOS-7, human embryonic kidney 293, tsA201, L929 and MEL cellsNAFemale Lewis rat (9-10 weeks of age)Proliferation assayNANA226223632012
1182SMRV-H peptideEVVLQNRRGLDLLTAEQGGICLALQERCCFYANKS35DNoneNoneNoneLinearProtein DerivedSquirrel monkey retrovirus (SMRV)NANot AvailableIn vitroU937, P2, JLS-V5NANANANANA32017491988
1183SRV-1 peptideEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedSimian retrovirus type-1NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1184SRV-2 peptideEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedSimian retrovirus type-2NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1185MPMVEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedMason-Pfizer monkey virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1186REV-AEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKS35LNoneNoneNoneLinearProtein DerivedReticuloendotheliosis-associated virus (REV-A)NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1187FeLVEVVLQNRRGLDILFLQEGGLCAALKEECCFYADHT35LNoneNoneNoneLinearProtein DerivedFeline leukemia virus (FeLV)NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1188Mo-MLVEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHT35LNoneNoneNoneLinearProtein DerivedMoloney murine leukemia virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1189RSVHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDH35LNoneNoneNoneLinearProtein DerivedRespiratory syncytial virusNANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1190HTLV-1QYAAQNRRGLDLLFWEQGGLCKALQEQCRFPNITN35LNoneNoneNoneLinearProtein DerivedHuman T-cell lymphotropic virus 1NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1191HTLV-2QYAAQNRRGLDLLFWEQGGLCKALQEQCCFLNISN35LNoneNoneNoneLinearProtein DerivedHuman T-cell lymphotropic virus 2NANot AvailableIn vitroHuman Lymphoblastoid Cell LineNANANANANA32017491988
1199LffX-IVGINVKCKHSRQCLKPCKDAGMRFGKCTNGKCHCTPK37LNoneNoneNoneLinearNaturalScorpion venomKv1.3 potassium channels of T cellshigh specificity binding Kv1.3 potassium channels of T cellsBothC0S-7 cells1.08 pMArthritic Lewis rats, EAE model of Wistar ratsNANANACN 101423550 B2012
1214SEQ ID NO: 3MLMYILAKFLHWLGGYILAKFLHWLGGYILAKFLHWL37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1216SEQ ID NO: 5AHGVILAKFLHWLSTAPPAHGVILAKFLHWLSTAPPA37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1217SEQ ID NO: 6QMNLILAKFLHWLCMTWNQMNLILAKFLHWLCMTW35LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1218SEQ ID NO: 7RLMYILAKFLHWLGPSRLMYILAKFLHWLGPS32LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1219SEQ ID NO: 8VHNVILAKFLHWLSTAPPVHNVILAKFLHWLSTAPPV37LNoneNoneNoneLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANANADE 102006025146 A12007
1268NACVCVCLLPRYPSAGVFTYLNTKIITFDSVLSCA33LNoneNoneNoneLinearProtein DerivedAmino acid sequences derived from a human native nucleotide sequence capable of expressing GIF (glycosylation-inhibiting factors)B-cellsGlycosylation inhibiting factor activity causing the suppression of immunoglobulin E (IgE) productionIn vitroMesenteric lymph node (MLN) cellsNALewis RatRosette inhibition assay, tests of the IgE-SF activityNANAEP 0255394 A21987
1304NoneCVCVCLLPRYPSAGVFTYLNTKIITFDSVLSKCA34LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1305NoneCVCVCIIPRYPSAGVFTYINTKIITFDSVISKCA35LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1306NoneCVCVCMMPRYPSAGVFTYMNTKIITFDSVMSKCA36LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1307NoneCVCVCLLPRYPSAGVFTYLNTKIITFDSVLSKCA37LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1308NoneCVCVCIIPRYPSAGVFTYINTKMMTFDSVISKCA38LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1309NoneCVCVCLLPRYPSAGVFTYLNTKLLTFDSVLSKCA39LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1310NoneCVCVCLLPRYPSAGVFTYLNTKIITFDSVLSKCA40LNoneNoneNoneLinearSyntheticNative nucloetide sequence capable of expressing GIF activityTissue harboring the parasiteInhibit glycosylation inhibiting factors, which inhibits IgE productionBothSpleen cellsNABALB/cHummoral Immune Response assayNANAUS 47496851988
1375SEQ ID2SCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC34LNoneNoneN-acetylation at position 18LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1376SEQ ID3CIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC33LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1377SEQ ID4RSCIDTIPKSECTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneN-acetylation at position 19LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1378SEQ ID5RSCIDTIPKSRCTAFECKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1379SEQ ID6RSCIDTIPKSRCTAFQCKKSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1380SEQ ID7RSCIDTIPKSRCTAFQCKHSMEYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1381SEQ ID8RSCIDTIPKSRCTAFQCKHSMKXYRLSFCRKTCGTC36LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1382SEQ ID9RSCIDTIPKSRCTAFQCKHSMAYRLSXCRKTCGTC35LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1383SEQ ID10RSCATIPKSRCTAAQCKHSMKYRLSFCRKRCGTC34LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1384SEQ ID11RSCIDSTIPKSRCTAAQKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1385SEQ ID12RSCADTIPKSRCTAAQCKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1386SEQ ID13SSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1387SEQ ID14RSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1388SEQ ID15RSCIDTIPKSQCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1389SEQ ID16RSCIDTIPKSRCTAAQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1390SEQ ID17RSCIDTIPKSQCTAWQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1391SEQ ID18RSCIDTIPKSQCTAFQCAHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1392SEQ ID19RSCIDTIPKSQCTAFQCKHSXKYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1393SEQ ID20RSCIDTIPKSRCTAFQCKHSMAYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1394SEQ ID21RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1395SEQ ID22RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = ornithineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1396SEQ ID23RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = homocitrullineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1397SEQ ID24RSCIDTIPKSRCTAFQCRHSMRYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1398SEQ ID25RSCIDTIPKSRCTAFQCKHSMKFRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000