Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID1080 | SequenceCSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | NamesCT | Nature of peptide or cargoCell penetrating peptide | AssayVertical Franz diffusion cell, HPLC | Tissue permeabilityCumulative amounts 0.67 ± 0.10 mg/cm2 and fluxes 0.67 ± 0.10 mg/cm2·h | Tissue SampleViable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | PUBMED ID22564052 |
| ID1081 | SequenceCSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | NamesCT | Nature of peptide or cargoCell penetrating peptide | AssayVertical Franz diffusion cell, HPLC | Tissue permeabilityCumulative amounts 0.33 ± 0.09 mg/cm2 and fluxes 0.11 ± 0.03 mg/cm2·h | Tissue SampleViable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | PUBMED ID22564052 |
| ID1082 | SequenceCSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | NamesCT | Nature of peptide or cargoCell penetrating peptide | AssayVertical Franz diffusion cell, HPLC | Tissue permeabilityCumulative amounts 0.26 ± 0.02 mg/cm2 and fluxes 0.04 ± 0.00 mg/cm2·h | Tissue SampleViable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | PUBMED ID22564052 |
| ID1113 | SequenceGGGARKKAAKAARKK AAKAARKKAAKAARK KAAKA | NamePOD-GFP [POD (peptide for ocular delivery)] | Nature of peptide or cargoCell penetrating peptide | AssayFluorescence microscopy | Tissue permeabilityGFP-fluorescence was 23.4 ±8.8, p < 0.05 | Tissue SampleEpidermis of skin of C57BL6/J mice | PUBMED ID19733192 |
| ID1215 | SequenceSVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | NameParathyroid Hormone (PTH) | Nature of peptide or cargoPTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | AssayFranz cell | Tissue permeability<1% PTH dissolved in normal saline recovered in the lower chamber of the Franz cell after 24 h | Tissue SampleSurgically obtained adult abdominal human epidermis | PUBMED ID12932245 |
| ID1216 | SequenceSVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | NameParathyroid Hormone (PTH) | Nature of peptide or cargoPTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | AssayFranz cell | Tissue permeability<1% PTH dissolved in propylene glycol recovered in the lower chamber of the Franz cell after 24 h | Tissue SampleSurgically obtained adult abdominal human epidermis | PUBMED ID12932245 |
| ID1217 | SequenceSVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | NameParathyroid Hormone (PTH) | Nature of peptide or cargoPTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | AssayFranz cell | Tissue permeability45% PTH formulated in Novasome A cream recovered in the lower chamber of the Franz cell after 24 h | Tissue SampleSurgically obtained adult abdominal human epidermis | PUBMED ID12932245 |
| ID1226 | SequenceCSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | NameSalmon calcitonin (sCT) | Nature of peptide or cargoA peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | AssayRadioimmunoassay | Tissue permeabilityArea Under the Curve0–120 min (ng·min/ml)=19.8±2.9 , Absolute Bioavailability (%)=33.2 , Relative Bioavailability (%)=68.6 | Tissue SampleStratum corneum of the stomach of SD male rats | PUBMED ID11337153 |
| ID1227 | SequenceCSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | NameSalmon calcitonin (sCT) | Nature of peptide or cargoA peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | AssayRadioimmunoassay | Tissue permeabilityArea Under the Curve0–120 min (ng·min/ml)=43.0±5.0 , Absolute Bioavailability (%)=37.0 , Relative Bioavailability (%)=76.5 | Tissue SampleStratum corneum of the stomach of SD male rats | PUBMED ID11337153 |
| ID1228 | SequenceCSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | NameSalmon calcitonin (sCT) | Nature of peptide or cargoA peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | AssayRadioimmunoassay | Tissue permeabilityArea Under the Curve0–120 min (ng·min/ml)=72.2±7.3 , Absolute Bioavailability (%)=32.5 , Relative Bioavailability (%)=67.2 | Tissue SampleStratum corneum of the stomach of SD male rats | PUBMED ID11337153 |
| ID1265 | SequenceSNLST-Asu-VLGKLSQELH KLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | AssayCalcium C-Test Wako kit, Ames method, Alkaline Phospha K-Test and ANOVA | Tissue permeabilityParameters studied: Ca(mg/dl)- 8.83±0.20/8.94±0.17(control), P(mg/dl)- 5.32±0.35/5.58±0.55(control) and Alkaline phosphatase- 23.69±1.16/18.83±0.75(control) | Tissue SampleAbdominal skin of female wistar rats | PUBMED ID8268857 |
| ID1266 | SequenceSNLST-Asu-VLGKLSQELH KLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | AssayCalcium C-Test Wako kit, Ames method, Alkaline Phospha K-Test and ANOVA | Tissue permeabilityParameters studied: Ca(mg/dl)- 8.80±0.27/8.94±0.17(control), P(mg/dl)- 5.22±0.36/5.58±0.55(control) and Alkaline phosphatase- 22.21±4.01/18.83±0.75(control) | Tissue SampleAbdominal skin of female wistar rats | PUBMED ID8268857 |
| ID1335 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=30.99±11.75 , Area under the first moment curve(mg.h2/dl)=371.41±159.80 , The mean residence time(h)=12.06±1.99 , Apparent bioavailability(%)=2.68. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1336 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=46.25±19.25 , Area under the first moment curve(mg.h2/dl)=623.71±233.74 , The mean residence time(h)=13.81±2.36 , Apparent bioavailability(%)=3.99. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1337 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=36.13±21.93 , Area under the first moment curve(mg.h2/dl)=445.49±248.06 , The mean residence time(h)=12.83±1.68 , Apparent bioavailability(%)=3.12. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1338 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=17.25±10.07 , Area under the first moment curve(mg.h2/dl)=271.52±106.34 , The mean residence time(h)=18.16±6.19 , Apparent bioavailability(%)=1.49. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1339 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=53.50±14.96 , Area under the first moment curve(mg.h2/dl)=752.04±298.40 , The mean residence time(h)=13.66±3.46 , Apparent bioavailability(%)=4.62. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1340 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=31.97±17.89 , Area under the first moment curve(mg.h2/dl)=505.37±238.24 , The mean residence time(h)=16.32±2.35 , Apparent bioavailability(%)=2.76. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1341 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=40.85±20.01 , Area under the first moment curve(mg.h2/dl)=513.32±292.53 , The mean residence time(h)=12.34±2.37 , Apparent bioavailability(%)=3.53. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1342 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=26.40±20.66 , Area under the first moment curve(mg.h2/dl)=341.64±271.20 , The mean residence time(h)=13.91±3.02 , Apparent bioavailability(%)=2.28. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1343 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=35.0216.72 , Area under the first moment curve(mg.h2/dl)=433.42±114.39 , The mean residence time(h)=13.37±3.66 , Apparent bioavailability(%)=3.02. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1344 | SequenceSNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | NameElcatonin | Nature of peptide or cargoIt stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Assayo-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Tissue permeabilityArea under the curve(mg.h/dl)=35.23±33.53 , Area under the first moment curve(mg.h2/dl)=490.35±444.31 , The mean residence time(h)=16.31±6.88 , Apparent bioavailability(%)=3.04. | Tissue SampleStratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | PUBMED ID2054872 |
| ID1381 | SequenceDLPVLQLTHPPGVRRV YHIQAGLPDPFQPPS | NameHSV-1 gD 22-52 (group-1) | Nature of peptide or cargoIntranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1382 | SequenceQPPSLPITVYAVLERA CRSVLLNAPSEAPQIVR | NameHSV-1 gD 49-82 (group-2) | Nature of peptide or cargoIntranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1385 | SequenceNKSLGACPIRTQPRW NYYDSFSAVSEDNLGF | NameHSV-1 gD 121-152 (group-1) | Nature of peptide or cargoIntranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1386 | SequenceEDNLGFLMHSPSFETSGT YLRLVKINDWTEITQF | NameHSV-1 gD 146-179 (group-2) | Nature of peptide or cargoIntranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1387 | SequenceITQFILEHRAKGSCKY ALPLRIPPSACLSPQ | NameHSV-1 gD 176-206 (group-3) | Nature of peptide or cargoIntranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1388 | SequenceSACLSPQAYQQGVTV DSIGMLPRFIPENQR TVAVY | NameHSV-1 gD 200-234 (group-2) | Nature of peptide or cargoIntranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1391 | SequenceAPQIPPNWHIPSIQDA ATPYHPPATPNNMGL | NameHSV-1 gD 287-317 (group-2) | Nature of peptide or cargoIntranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | AssayFACS | Tissue permeabilityDetectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Tissue SampleNasal cavity of New Zealand White rabbits | PUBMED ID20089796 |
| ID1504 | SequenceDLPVLQLTDPPGVRRV YHIQAGLPDPFQPPS | NamegD 22-52 (group 1) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityInduced higher IgA response. | Tissue Sampleeye | PUBMED ID15603887 |
| ID1505 | SequenceQPPSLPITVYYAVLERA CRSVLLNAPSEAPQIVR | NamegD 49-82 (group 1) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityGave lower but significant responses (p <0.05) | Tissue Sampleeye | PUBMED ID15603887 |
| ID1508 | SequenceNKSLGACPIRTQPRWN YYDSFSAVSEDNLGFL | NamegD 121-152 (group 2) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityGave lower but significant responses (p <0.05) | Tissue Sampleeye | PUBMED ID15603887 |
| ID1509 | SequenceEDNLGFLMHAPAFETAG TYLRLVKINDWTEITQF | NamegD 146-179 (group 2) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityInduced higher IgA response | Tissue Sampleeye | PUBMED ID15603887 |
| ID1510 | SequenceTQFILEHRAKGSCKY ALPLRIPPSACLSPQ | NamegD 176-206 (group 2) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityInduced higher IgA response | Tissue Sampleeye | PUBMED ID15603887 |
| ID1511 | SequenceSACLSPQAYQQGVTV DSIGMLPRFIPENQR TVAVY | NamegD 200-234 (group 3) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityGave lower but significant responses (p <0.05) | Tissue Sampleeye | PUBMED ID15603887 |
| ID1513 | SequenceAPQIPPNWHIPSIQDA ATPYHPPATPNNMGL | NamegD 287-317 (group 3) | Nature of peptide or cargonot mentioned | AssayELISA, Antibody assay, Peptide specific T-cell assays | Tissue permeabilityGave lower but significant responses (p <0.05) | Tissue Sampleeye | PUBMED ID15603887 |
| ID1525 | SequenceGGG(ARKKAAKA)4 | NameL-POD (lissamine- conjugated peptide for ocular delivery) | Nature of peptide or cargoA novel cell-penetrating peptide POD has the ability to penetrate and deliver fluorophores, siRNA, DNA and quantum dots to cells in culture and retinal and ocular tissues in vivo. It also acts as a microbicide, potentially providing a safer and more efficacious method of delivering molecules t | AssayFluorescence-activated cell sorting (FACS), Vital staining with Lissamine | Tissue permeabilityL-POD bound strongly to the cornea, sclera and the dura of the optic nerve in vivo. In contrast, lissamine only weakly stained the cornea and sclera and did not stain the dura of the optic nerve. | Tissue SampleCornea of male C57BL/6J mice | PUBMED ID17923842 |
| ID1606 | SequenceCSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | NameSalmon calcitonin | Nature of peptide or cargoNot mentioned | AssayELISA, noncompartmental analysis using WinNonlin | Tissue permeabilityIontophoretic patches delivered SCT at an average infusion rate of 177.9±58.7 ng/(min kg) and an average steady state concentration of 7.58±1.35 ng/ml was achieved. | Tissue SampleAbdominal skin of hairless rats | PUBMED ID15907605 |
| ID1644 | SequenceCGNLSTCMLGTYTQ DFNKFHTFPQTAIGVGAP | Namethyrocalcitonin | Nature of peptide or cargoNot mentioned | Assaypermeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from polyacrylamide hydrogels was measured. | Tissue permeability6.20 (cm/sec) * 10 8 | Tissue Sampleskin of hairless rat | PUBMED ID8321834 |
| ID1647 | SequenceCGNLSTCMLGTYTQ DFNKFHTFPQTAIGVGAP | Namethyrocalcitonin | Nature of peptide or cargoNot mentioned | Assaypermeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from p-HEMA hydrogels was measured. | Tissue permeability1.95(cm/sec) * 10 8 | Tissue Sampleskin of hairless rat | PUBMED ID8321834 |