| ID | 1644 | |
| PMID | 8321834 | |
| Year | 1992 | |
| Sequence | CGNLSTCMLGTYTQ DFNKFHTFPQTAIGVGAP | |
| Name | thyrocalcitonin | |
| Length | 32 | |
| N-Terminal Modification | Free | |
| C-Terminal Modification | Free | |
| Linear/ Cyclic | Linear | |
| Chirality | L | |
| Chemical Modification | None | |
| Origin of Peptide | Synthetic human calcitonin | |
| Nature of Peptide/Cargo | Not mentioned | |
| Mechanism | Not mentioned | |
| Cargo Sequence/Structure | No cargo | |
| Name of cargo | Not applicable | |
| Assay | permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from polyacrylamide hydrogels was measured. | |
| Enhancer | PH 3.6 | |
| Properties of enhancer | Not mentioned | |
| Concentration | 0.65 uM | |
| Incubation time | 36 hrs | |
| Tissue permeability (value with units) | 6.20 (cm/sec) * 10 8 | |
| Tissue Sample | skin of hairless rat | |
| Ex vivo/In vivo/In vitro | in vitro | |
| STRUCTURE |
| |
| SMILES | N[C@@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N [C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C=O) CCC)C)C(C)C)[C@H](CC)C)C)[C@H] (O)C)CCC(=O)N)CCC2)Cc2ccccc2)[C@H](O)C)C c2[nH]cnc2)Cc2ccccc2)CCCCN)CC(=O)N)Cc2ccccc2) CC(=O)O)CCC(=O)N)[C@H](O)C)Cc2ccc(cc2)O) [C@H](O)C)CC(C)C)CCSC)CSSC1)[C@H](O) C)CO)CC(C)C)CC(=O)N | |