ID | 1113 | |
PMID | 19733192 | |
Year | 2010 | |
Sequence | GGGARKKAAKAARKK AAKAARKKAAKAARK KAAKA | |
Name | POD-GFP [POD (peptide for ocular delivery)] | |
Length | 35 | |
N-Terminal Modification | Free | |
C-Terminal Modification | Free | |
Linear/ Cyclic | Linear | |
Chirality | L | |
Chemical Modification | None | |
Origin of Peptide | None | |
Nature of Peptide/Cargo | Cell penetrating peptide | |
Mechanism | Not mentioned | |
Cargo Sequence/Structure | MSKGEELFTGVVPVLVELDGDVNGQKFSVSGEGEGDATYGKLTLNFICTTGKLPVPWPTLVTTFSYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFYKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKMEYNYNSHNVYIMGDKPKNGIKVNFKIRHNIKDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMILLEFVTAARITHGMDELYK | |
Name of cargo | GFP | |
Assay | Fluorescence microscopy | |
Enhancer | None | |
Properties of enhancer | Not applicable | |
Concentration | 40µg | |
Incubation time | 24 hours | |
Tissue permeability (value with units) | GFP-fluorescence was 23.4 ±8.8, p < 0.05 | |
Tissue Sample | Epidermis of skin of C57BL6/J mice | |
Ex vivo/In vivo/In vitro | in vivo | |
STRUCTURE |
| |
SMILES | NCC(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C=O)C)CCCCN)C)C)CCCCN)CCCCN) CCCNC(=N)N)C)C)CCCCN)C)C)CCCCN)CCCCN)CCCNC (=N)N)C)C)CCCCN)C)C)CCCCN)CCCCN)CCCNC(=N) N)C)C)CCCCN)C)C)CCCCN)CCCCN)CCCNC(=N)N)C |