| ID | 1606 | |
| PMID | 15907605 | |
| Year | 2005 | |
| Sequence | CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | |
| Name | Salmon calcitonin | |
| Length | 32 | |
| N-Terminal Modification | Free | |
| C-Terminal Modification | Free | |
| Linear/ Cyclic | Linear | |
| Chirality | L | |
| Chemical Modification | None | |
| Origin of Peptide | Synthetic peptide | |
| Nature of Peptide/Cargo | Not mentioned | |
| Mechanism | Not mentioned | |
| Cargo Sequence/Structure | None | |
| Name of cargo | Not applicable | |
| Assay | ELISA, noncompartmental analysis using WinNonlin | |
| Enhancer | iontophoresis using iontophoretic patches with built-in proprietary Zn/AgCl electrodes were used. Citrate buffer, pH 4.0 were used to impart charge for anodal iontophoresis | |
| Properties of enhancer | Eases delivery | |
| Concentration | 1mg/ml | |
| Incubation time | 2 hrs | |
| Tissue permeability (value with units) | Iontophoretic patches delivered SCT at an average infusion rate of 177.9±58.7 ng/(min kg) and an average steady state concentration of 7.58±1.35 ng/ml was achieved. | |
| Tissue Sample | Abdominal skin of hairless rats | |
| Ex vivo/In vivo/In vitro | in vivo | |
| STRUCTURE |
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| SMILES | N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N [C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H] (C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O) N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C (=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C (=O)N[C@H](C=O)CCC)[C@H](O)C)CO)[C@H](O)C)CC (=O)N)[C@H](O)C)CCCNC(=N)N)CCC)Cc1ccc(cc1)O) [C@H](O)C)CCC(=O)N)CC(C)C)CCCCN)Cc1[nH]cnc1)CC (C)C)CCC(=O)O)CCC(=O)N)CO)CC(C)C)CCCCN) CC(C)C)C(C)C)CS)[C@H](O)C)CO)CC(C)C) CC(=O)N)CO)CS | |