Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_1512 | NACHT Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | AAMP | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1512 | NACHT Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | AAMP | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1535 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q9Y239.fasta | Q9Y239 | 953 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1535 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q9Y239.fasta | Q9Y239 | 953 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1536 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q8BHB0.fasta | Q8BHB0 | 953 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1536 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q8BHB0.fasta | Q8BHB0 | 953 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1537 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q9HC29.fasta | Q9HC29 | 1040 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1537 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q9HC29.fasta | Q9HC29 | 1040 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1538 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q8K3Z0.fasta | Q8K3Z0 | 1020 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1538 | Peptidoglycan (PGN) Click for more detail | Gram-positive bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | PGN is known to be a potent activator of NF-κB and TNF-α through TLR2 | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells and also in nonimmune cells, for example in epithelium | Intracellular receptors | Q8K3Z0.fasta | Q8K3Z0 | 1020 | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. | NA | 24829146 | 2014 | Pubchem_assay |
| PRRID_1547 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | peripheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells | intracellular receptors | Q9HC29.fasta | Q9HC29 | 1040 | recognizes fragments of the bacterial cell wall. | Luciferase assay | 24790089 | 2014 | Pubchem_assay |
| PRRID_1547 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | peripheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells | intracellular receptors | Q9HC29.fasta | Q9HC29 | 1040 | recognizes fragments of the bacterial cell wall. | Luciferase assay | 24790089 | 2014 | Pubchem_assay |
| PRRID_1548 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | triggers immune responses | Nod-like receptor 1 (NLR1) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells | intracellular receptors | NA | NA | NA | triggering of these receptors induces activation of the NF-κB pathway and consequently, an immune response | NA | 24779390 | 2014 | NA |
| PRRID_1548 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | triggers immune responses | Nod-like receptor 1 (NLR1) | NOD-like receptor (NLR) | Mice | lymphocytes, macrophages, dendritic cells | intracellular receptors | NA | NA | NA | triggering of these receptors induces activation of the NF-κB pathway and consequently, an immune response | NA | 24779390 | 2014 | NA |
| PRRID_1550 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | triggers immune responses | Nod-like receptor 1 (NLR1) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells | intracellular receptors | NA | NA | NA | triggering of these receptors induces activation of the NF-κB pathway and consequently, an immune response | NA | 24779390 | 2014 | NA |
| PRRID_1550 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | triggers immune responses | Nod-like receptor 1 (NLR1) | NOD-like receptor (NLR) | Human | lymphocytes, macrophages, dendritic cells | intracellular receptors | NA | NA | NA | triggering of these receptors induces activation of the NF-κB pathway and consequently, an immune response | NA | 24779390 | 2014 | NA |
| PRRID_1554 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | NA | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1554 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | NA | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1560 | Peptidoglycan (PGN) Click for more detail | Gram negative Bacteria (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | European and African Children | most adult tissues | signals via a caspase- activated recruitment domain (CARD) | Q9Y239.fasta | Q9Y239 | 953 | induce autophagy and inflammatory responses in host cells. | ELISA | 24746552 | 2014 | Pubchem_assay |
| PRRID_1560 | Peptidoglycan (PGN) Click for more detail | Gram negative Bacteria (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | European and African Children | most adult tissues | signals via a caspase- activated recruitment domain (CARD) | Q9Y239.fasta | Q9Y239 | 953 | induce autophagy and inflammatory responses in host cells. | ELISA | 24746552 | 2014 | Pubchem_assay |
| PRRID_1563 | CARDs Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1563 | CARDs Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 25520185 | 2014 | NA |
| PRRID_1650 | Tri-DAP Click for more detail | Gram-positive and negative bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activate NF-κB | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | macrophages and mesothelial cells | serine/threonine RIP2 (RICK, CARDIAK) kinase | Q8BHB0.fasta | Q8BHB0 | 953 | interacts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6 | ELISA | 24766550 | 2014 | Pubchem_assay |
| PRRID_1650 | Tri-DAP Click for more detail | Gram-positive and negative bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activate NF-κB | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | macrophages and mesothelial cells | serine/threonine RIP2 (RICK, CARDIAK) kinase | Q8BHB0.fasta | Q8BHB0 | 953 | interacts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6 | ELISA | 24766550 | 2014 | Pubchem_assay |
| PRRID_1651 | Tri-DAP Click for more detail | Gram-positive and negative bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activate NF-κB | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | macrophages and mesothelial cells | serine/threonine RIP2 (RICK, CARDIAK) kinase | Q8BHB0.fasta | Q8BHB0 | 953 | interacts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6 | ELISA | 24766550 | 2014 | Pubchem_assay |
| PRRID_1651 | Tri-DAP Click for more detail | Gram-positive and negative bacteria | CC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N | NA | Peptide | Natural | activate NF-κB | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Human | macrophages and mesothelial cells | serine/threonine RIP2 (RICK, CARDIAK) kinase | Q8BHB0.fasta | Q8BHB0 | 953 | interacts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6 | ELISA | 24766550 | 2014 | Pubchem_assay |
| PRRID_1895 | 6-O-stearoyl-MDP (L18- MDP) Click for more detail | NA | CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C2 (NLRC2) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_1895 | 6-O-stearoyl-MDP (L18- MDP) Click for more detail | NA | CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptide | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C2 (NLRC2) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_1899 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1899 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1900 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | NA | NA | Q9C000.fasta | Q9C000 | 1473 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1900 | Ab Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | Cellular injury and necrosis | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | NA | NA | Q9C000.fasta | Q9C000 | 1473 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1911 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1911 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1912 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1912 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1913 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1913 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ↑ in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1914 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1915 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1915 | Amyloid-β fibrils Click for more detail | NA | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Damage-associated molecular patterns (DAMPs) | Natural | Immunostimulant | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ↑, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1917 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Rat | Hippocampus | NA | D9I2G4 .fasta | D9I2G4 | 1218 | NLRP1 inflammasome activation in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1918 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | hippocampus (neurons) | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1918 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | hippocampus (neurons) | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1919 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | models of AD | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1919 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | models of AD | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1920 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1920 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q2LKU9.fasta | Q2LKU9 | 1182 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1921 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | Brain | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1921 | Anthrax lethal toxin Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor protein 1 (NLRP1) | NOD-like receptor (NLR) | Human | Brain | NA | Q9C000.fasta | Q9C000 | 1473 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1922 | Anthrax lethal toxin Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | NALP3/ cryopyrin | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_1922 | Anthrax lethal toxin Click for more detail | Bacteria | NA | NA | Protein | Natural | NA | NALP3/ cryopyrin | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_1926 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1926 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Microglia | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NLRP3 inflammasome activation in AD models | NA | 28805121 | 2017 | Pubchem_assay |
| PRRID_1927 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1927 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | cortical neurons (cell culture, stroke model) | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1928 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1928 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Brain | NA | Q96P20.fasta | Q96P20 | 1036 | protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1929 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Rat | primary astrocytes | NA | D4A523.fasta | D4A523 | 1035 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1930 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1930 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | substantia nigra | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | protein ‚Üë, activation of NLRP3 inflammasome in PD models | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_1931 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | P2X7R | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1931 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | P2X7R | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1932 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1932 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Activate human dendritic cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Dendritic cells | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1933 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | P2X7R | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1933 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | P2X7R | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1934 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1934 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β and IL-18 by human monocytes | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Monocyte | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1935 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | P2X7R | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1935 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | P2X7R | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1936 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1936 | ATP Click for more detail | NA | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O | NA | Damage-associated molecular patterns (DAMPs) | Natural | Induce the secretion of IL-1β by murine and human neutrophils | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Neutrophils | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1952 | Bacterial MDP Click for more detail | RSV, IAV, and HCMV (virus) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Likely tetramerization into washer- locker structure | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | Cytoplasm. Macrophages, monocytes, Paneth cells, DCs | NA | Q9HC29.fasta | Q9HC29 | 1040 | RIP2-IKKs-NF-jB | NA | 28374903 | 2017 | Pubchem_assay |
| PRRID_1952 | Bacterial MDP Click for more detail | RSV, IAV, and HCMV (virus) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Likely tetramerization into washer- locker structure | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) | NOD-like receptor (NLR) | Human | Cytoplasm. Macrophages, monocytes, Paneth cells, DCs | NA | Q9HC29.fasta | Q9HC29 | 1040 | RIP2-IKKs-NF-jB | NA | 28374903 | 2017 | Pubchem_assay |
| PRRID_1959 | Biglycan Click for more detail | Proteoglycan (others) | MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT | 238 | Carbohydrate | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1959 | Biglycan Click for more detail | Proteoglycan (others) | MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT | 238 | Carbohydrate | Natural | involved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunity | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 29290139 | 2017 | NA |
| PRRID_1962 | Biglycan Click for more detail | NA | MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT | 238 | Carbohydrate | Natural | Induce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophages | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Macrophages | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1962 | Biglycan Click for more detail | NA | MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYVRSWEEPAGLQQRAGVRALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLT | 238 | Carbohydrate | Natural | Induce the secretion of TNF-α, MIP-2 and IL-1β by murine macrophages | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Mice | Macrophages | NA | Q8R4B8.fasta | Q8R4B8 | 1033 | NA | NA | 28961019 | 2017 | Pubchem_assay |
| PRRID_1981 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1981 | Chromogranin A Click for more detail | All vertebrates(others) | NA | NA | Damage-associated molecular patterns (DAMPs) | Natural | activate microglial cells | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | NA | NA | Q96P20.fasta | Q96P20 | 1036 | Activate NF-KB | NA | 28049142 | 2017 | Pubchem_assay |
| PRRID_1987 | CpG motif Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | human peripheral B­lymphocytes | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 29170665 | 2017 | Pubchem_assay |
| PRRID_1987 | CpG motif Click for more detail | NA | NA | NA | Protein | Natural | NA | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | human peripheral B­lymphocytes | NA | Q96P20.fasta | Q96P20 | 1036 | NA | NA | 29170665 | 2017 | Pubchem_assay |
| PRRID_1993 | d-lactoyl-l-Ala-d-Glu-meso-DAP-l-Gly Click for more detail | NA | NA | NA | Agonist | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C1 (NLRC1) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_1993 | d-lactoyl-l-Ala-d-Glu-meso-DAP-l-Gly Click for more detail | NA | NA | NA | Agonist | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C1 (NLRC1) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_2000 | diaminopimelic acid (DAP) Click for more detail | Gram-negative and Gram-positive bacteria | C(CC(C(=O)O)N)CC(C(=O)O)N | NA | Agonist | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C1 (NLRC1) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_2000 | diaminopimelic acid (DAP) Click for more detail | Gram-negative and Gram-positive bacteria | C(CC(C(=O)O)N)CC(C(=O)O)N | NA | Agonist | Synthetic | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines | Nod-like receptor C1 (NLRC1) | NOD-like receptor (NLR) | Human | Intracellular | C-terminal leucine-rich regions and NOD domains | NA | NA | NA | triggering production of β-defensins via an NF-κB signaling pathway | NA | 28776416 | 2017 | NA |
| PRRID_2009 | dsRNA Click for more detail | Hepatitis C Virus (virus) | NA | NA | Nucleic Acid | Natural | Activation of NOD1 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | Macrophages | nucleotide-binding oligomerization domain | Q8BHB0.fasta | Q8BHB0 | 953 | Independent of MAVS; likely dsRNA produced by NS5B polymerase | NA | 28823510 | 2017 | Pubchem_assay |
| PRRID_2009 | dsRNA Click for more detail | Hepatitis C Virus (virus) | NA | NA | Nucleic Acid | Natural | Activation of NOD1 | Nucleotide Binding Oligomerization Domain Containing 1 (Nod1) | NOD-like receptor (NLR) | Mice | Macrophages | nucleotide-binding oligomerization domain | Q8BHB0.fasta | Q8BHB0 | 953 | Independent of MAVS; likely dsRNA produced by NS5B polymerase | NA | 28823510 | 2017 | Pubchem_assay |
| PRRID_2012 | dsRNA Click for more detail | flu virus, SeV and bacteria | NA | NA | Nucleic Acid | Natural | potassium efflux-NEK7 involved NLRP3 inflammasome complex | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Cytoplasm. Ubiquitously expressed | NA | Q96P20.fasta | Q96P20 | 1036 | ASC-inflammasome- caspase-1-IL-1/IL-18 | NA | 28374903 | 2017 | Pubchem_assay |
| PRRID_2012 | dsRNA Click for more detail | flu virus, SeV and bacteria | NA | NA | Nucleic Acid | Natural | potassium efflux-NEK7 involved NLRP3 inflammasome complex | Nod-like receptor P3 (NLRP3) | NOD-like receptor (NLR) | Human | Cytoplasm. Ubiquitously expressed | NA | Q96P20.fasta | Q96P20 | 1036 | ASC-inflammasome- caspase-1-IL-1/IL-18 | NA | 28374903 | 2017 | Pubchem_assay |
| PRRID_2040 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | NAIP5/NLRC4 inflammasome receptor | NOD-like receptor (NLR) | Human | intracellular | NA | NA | NA | NA | Recognizes flagellin and bind it. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | NA |
| PRRID_2040 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | Innate immunity elicitor | NAIP5/NLRC4 inflammasome receptor | NOD-like receptor (NLR) | Human | intracellular | NA | NA | NA | NA | Recognizes flagellin and bind it. | Co-immunoprecipitataion Binding assay | 28827825 | 2017 | NA |
| PRRID_2042 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Nod-like receptor C4 (NLRC4) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2042 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | Nod-like receptor C4 (NLRC4) | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2047 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | IPAF | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2047 | Flagellin Click for more detail | Bacteria | MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR | 495 | Protein | Natural | NA | IPAF | NOD-like receptor (NLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |