Primary information |
---|
PRRID | PRRID_2000 |
Ligand Name | diaminopimelic acid (DAP) |
Source | Gram-negative and Gram-positive bacteria |
Sequence of ligand | C(CC(C(=O)O)N)CC(C(=O)O)N |
Length | NA |
Type | Agonist |
Occurence | Synthetic |
Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
Name of receptor | Nod-like receptor C1 (NLRC1) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | Intracellular |
Domain | C-terminal leucine-rich regions and NOD domains |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | triggering production of β-defensins via an NF-κB signaling pathway |
Assay used | NA |
PMID | 28776416 |
Year of Publication | 2017 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_2000 |
Ligand Name | diaminopimelic acid (DAP) |
Source | Gram-negative and Gram-positive bacteria |
Sequence of ligand | C(CC(C(=O)O)N)CC(C(=O)O)N |
Length | NA |
Type | Agonist |
Occurence | Synthetic |
Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
Name of receptor | Nod-like receptor C1 (NLRC1) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | Intracellular |
Domain | C-terminal leucine-rich regions and NOD domains |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | triggering production of β-defensins via an NF-κB signaling pathway |
Assay used | NA |
PMID | 28776416 |
Year of Publication | 2017 |
Pubchem assay | NA |