| Primary information |
|---|
| PRRID | PRRID_1895 |
| Ligand Name | 6-O-stearoyl-MDP (L18- MDP) |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
| Length | NA |
| Type | Peptide |
| Occurence | Synthetic |
| Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
| Name of receptor | Nod-like receptor C2 (NLRC2) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Intracellular |
| Domain | C-terminal leucine-rich regions and NOD domains |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | triggering production of β-defensins via an NF-κB signaling pathway |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | NA |
| Primary information |
|---|
| PRRID | PRRID_1895 |
| Ligand Name | 6-O-stearoyl-MDP (L18- MDP) |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
| Length | NA |
| Type | Peptide |
| Occurence | Synthetic |
| Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
| Name of receptor | Nod-like receptor C2 (NLRC2) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Intracellular |
| Domain | C-terminal leucine-rich regions and NOD domains |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | triggering production of β-defensins via an NF-κB signaling pathway |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | NA |