Primary information |
---|
PRRID | PRRID_1547 |
Ligand Name | Peptidoglycan (PGN) |
Source | Bacteria |
Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
Length | NA |
Type | Peptidoglycan |
Occurence | Natural |
Role of Ligand | elicit innate immune response |
Name of receptor | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | peripheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells |
Domain | intracellular receptors |
Sequence of Receptor | Q9HC29.fasta |
Swiss prot ID | Q9HC29 |
Length Of Receptor | 1040 |
Function | recognizes fragments of the bacterial cell wall. |
Assay used | Luciferase assay |
PMID | 24790089 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1547 |
Ligand Name | Peptidoglycan (PGN) |
Source | Bacteria |
Sequence of ligand | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N |
Length | NA |
Type | Peptidoglycan |
Occurence | Natural |
Role of Ligand | elicit innate immune response |
Name of receptor | Nucleotide Binding Oligomerization Domain Containing 2 (Nod2) |
Type of receptor | NOD-like receptor (NLR) |
Source | Human |
Localization | peripheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells |
Domain | intracellular receptors |
Sequence of Receptor | Q9HC29.fasta |
Swiss prot ID | Q9HC29 |
Length Of Receptor | 1040 |
Function | recognizes fragments of the bacterial cell wall. |
Assay used | Luciferase assay |
PMID | 24790089 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |