Detailed description page of PRRDB2.0

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PRRID_1547 details
Primary information
PRRIDPRRID_1547
Ligand NamePeptidoglycan (PGN)
SourceBacteria
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorNucleotide Binding Oligomerization Domain Containing 2 (Nod2)
Type of receptorNOD-like receptor (NLR)
Source Human
Localizationperipheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells
Domainintracellular receptors
Sequence of ReceptorQ9HC29.fasta
Swiss prot IDQ9HC29
Length Of Receptor1040
Functionrecognizes fragments of the bacterial cell wall.
Assay usedLuciferase assay
PMID24790089
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1547
Ligand NamePeptidoglycan (PGN)
SourceBacteria
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorNucleotide Binding Oligomerization Domain Containing 2 (Nod2)
Type of receptorNOD-like receptor (NLR)
Source Human
Localizationperipheral blood mononuclear cells such as macrophages, granulocytes, dendritic cells, and along the intestinal epithelial cells
Domainintracellular receptors
Sequence of ReceptorQ9HC29.fasta
Swiss prot IDQ9HC29
Length Of Receptor1040
Functionrecognizes fragments of the bacterial cell wall.
Assay usedLuciferase assay
PMID24790089
Year of Publication2014
Pubchem assayPubchem_assay