Detailed description page of PRRDB2.0

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PRRID_1650 details
Primary information
PRRIDPRRID_1650
Ligand NameTri-DAP
SourceGram-positive and negative bacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N
LengthNA
TypePeptide
OccurenceNatural
Role of Ligandactivate NF-κB
Name of receptorNucleotide Binding Oligomerization Domain Containing 1 (Nod1)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationmacrophages and mesothelial cells
Domainserine/threonine RIP2 (RICK, CARDIAK) kinase
Sequence of ReceptorQ8BHB0.fasta
Swiss prot IDQ8BHB0
Length Of Receptor953
Functioninteracts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6
Assay usedELISA
PMID24766550
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1650
Ligand NameTri-DAP
SourceGram-positive and negative bacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)N
LengthNA
TypePeptide
OccurenceNatural
Role of Ligandactivate NF-κB
Name of receptorNucleotide Binding Oligomerization Domain Containing 1 (Nod1)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationmacrophages and mesothelial cells
Domainserine/threonine RIP2 (RICK, CARDIAK) kinase
Sequence of ReceptorQ8BHB0.fasta
Swiss prot IDQ8BHB0
Length Of Receptor953
Functioninteracts with IKK to trigger the activation of NF-kB and the production of inflammatory cytokines, such as TNF-a and IL-6
Assay usedELISA
PMID24766550
Year of Publication2014
Pubchem assayPubchem_assay