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The total number entries retrieved from this search are 315
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2434AZI1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.46 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2435LOC654342RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.58 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2436TPRRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.86 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2437CENPIRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.69 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2438CBX1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.68 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2439CCHCR1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.57 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2440STMN1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.52 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2441AUP1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.33 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2442IQGAP3RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.24 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2443NFYARNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.41 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2444TH1LRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.54 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2445SLC39A4RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 4.42 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2446MEIS2RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.28 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2447CITRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.26 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2448KIAA0286RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.99 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2449FAM48ARNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.83 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2450CCNFRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.72) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2451IPO9RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.64 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2452MTA3RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.61 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2453CSRP2BPRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.57 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2454XPO1RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.44 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2455C14orf93RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.43 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2456C5orf13RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.56 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2457EHMT2RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.80 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2458STX6RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.24 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2459MCM8RNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 2.34 ) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2460MEF2BRNAsHumanUpregulated in highly invasive HCC than less-invasive HCC (with fold change of 1.49) Prognosticless (L) invasive HCC v/s highly (H) invasive HCC; associated with survival of patients p < 0.01Tissue19945130
2461FAM34A, NARS, HSPC152, GRP58, GBA, PVRL2, RPS17, LAMR1, GNB1, AHNAK, GRCC10, SPTAN1, CTSC, NSE1, COP1, NDRG1, HSPA5, SPARC, ATP5J2, KIAA0663, CD24, NUDT3, CANXRNAsHumanDownregulated in among all types HCC v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue16391793
2462SMYD3, FABP1, Ceruloplasmin, A2M, IGFBP, PPAP2B, SHMT, PHLDA1, APOA1, SOCS2, ETS2, MT2A, CYP39A1, HAMP, CYP2C9, SLC22A1, PLG, GAMT, FGG, KRT8, IFITM1, C1R, FGB, FGA, GC (vitamin D binding protein), SERPINA3, WAC,RNAsHumanUpregulated in among all types HCC v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue16391793
2463CLURNAsHumanUpregulated in metastatic HCC than primary HCC Diagnostic and PrognosticPrimary and metastatic HCC p < 0.001Cell line and Tissue16247463
2464EGR3, MFAP3, EST, MMP9, PDCD4, EST, FLJ37853, ARHE, MAD2L1, NMNAT2, FLJ22016, SND1, MIDORI, FLJ36229, MGST2, CTPS2, OASL, HK2, EEF2, Taxilin, NT5C, CLNS1A, UNC5B, TSC, TNFSF6, KIAA1691, S100A10, ATP6V1D, ASB4, AGR2, KIAA0205, JJAZ1, LOC285859, KIAA0157, PPA2, eIF3k, SGKL, BLMH, ERG-1, BRCA2, PPP2R2ARNAsHumanDifferentially expressed (14 Upregulated and 49 Downregulated) in treatment responder v/s non-responders Predictivetreatment responder v/s non-responders p < 0.01Tissue15447987
2465GPC3, CAP2, UBD, MT1F, PTDSS1, RDS, ID1, NNMT, AA127809, PRRG2, ACAA1, SLC22A1, BE779749, FACL2, PRLR, C8orf4, C6, CCNH, AK022114, CBFA2T3, EPAS1, API5, SULT2A1, PGM1, C9, NQO1, C1R, PMS1, DSCR1, PPP1R2, GOT1, ZNF6, AI831040, GCLC, MYOZ2, HMGCL, UBE4A, SERPING1, PLG, ADFP, RODH, MARCO, C9orf59, BG71RNAsHumanDifferentially expressed (GPC3, CAP2, UBD Upregulated and rest 41 are Downregulated) in tumor v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.001Tissue15607117
2466MT1B, MT1E, MT1L, CP, ABCA1, CACNB3, PROS1, CPB2, SERPINC1, LACI, MDK, C6, C9, CD5L, GPR126, IL1RAP, DYRK3, PCDH17, TACSTD1, UAP1, C20orf3, CFL2, FLJ12666, KIAA0843, MRC1, NAT2, MYO1B, SIPL, SRD5A2, USP1,RNAsHumanDifferentially expressed (PCDH17, MDK, TACSTD1 Upregulated and rest 27 are Downregulated) in High-risk individuals with cirrhosis v/s patients with HCC PrognosticHigh-risk individuals with cirrhosis v/s patients with HCC p < 0.0003Tissue14768006
2472AURKBProtein and RNAsHumanUpregulated in HCC tissues in association with aggressive recurrence v/s non-recurrence PrognosticAggressive recurrence HCC v/s non-recurrence HCC p < 0.001Tissue18311747
2483MYO1D, EST, PDGF-B, LOC113246, SPTAN1, MGC19556, IL6R, PRPSAP1, PDCD6IP, AHNAK, BCL2L11, GPAA1, c-fos, SLC11A2, LOC51235, PRPF8, CD36L1, KIAA1055, HNRPDL, NDRG1, NARS, PABPC4, RDBP, CALM2, PDCD6, C1R, ALB, MT1G, CED-6, AMACR, A2M, FGG, SUPV3L1, PHLDA1, NBP, HAMP, HCS, KIAA0635, ECHS1, SHMT1, NNMT, ARNAsHumanDifferentially expressed between HCC and non-tumor liver tissue DiagnosticHCC v/s non-tumor p < 0.01Tissue14642619
2484SOX6, ITIH4, HDGF, SKIP1, RBP4, LOC92033, UGT2B7, FABP1, GATM, UQCRC1, UK114, CP, PBEF, KAL1, CES2, GPX4, UGT1A4, RCL, PABPC1, EST, FGA, RARRES2, SLC22A, SRP14, FLJ14294, cyclin, CA2, CLDN1, FTL, FLJ10004, CYP3A5, ARHGEF12, TDO2, NDUFB2, TEGT, SPR, PCK2, MGC13114, EST, MTHFS, F2, FLJ22313, C9orf5, HRNAsHumanDifferentially expressed between HCC and normal tissues DiagnosticHCC v/s normal p < 0.01Tissue14642619
2485IGFBP3, c-fos, p21RNAsHumanDifferentially expressed between HCC and non-tumor liver tissue DiagnosticHCC v/s non-tumor p < 0.01Tissue14642619
2486p53, cyclin D1RNAsHumanDifferentially expressed between HCC and normal tissues DiagnosticHCC v/s normal p < 0.01Tissue14642619
2499SEMA3F, DDX17, TNFAIP, PDGFRA, VIM, LAPTM5, CCND2, HLADRA, MEF2C, Staf50, SGK, REL,RNAsHumanDiffrenetially Expressed between recurrent and non-recurrent HCC PrognosticEarly intrahepatic recurrence and non-recurrence HCC p < 0.05Tissue12648972
2500RYBP, ATP1B3, TMC, ZNF567, GPR108, CD19, SPINK1, CDC2L6, RSRC1, METAP, GPC3, SNHG11, RY1, CRELD2, GLUL, SERPINB1, TRMT6, UNC13D, E4F1--E4F, SLC22A2, CNIH4, TK1, MAFB, PPP1CB, DNTTIP2, ARID4B, SMARCC2, PRO1386, TRIOBP, VARS, ITGA5, TERF1, PURA, TUBA1B, SNRPE, RRAGD, VWF, GLRX3, ILF2,RNAsHumanUpregulated in HCV related HCC than normal control (With 3-fold change) DiagnosticHCV related HCC v/s normal control p < 0.01Tissue19821982
2501NMNAT3, OASL, TMPRSS3, MFSD7, AEBP1, UBD, S100A4, C1orf151, CRIP1, ASCC3, ZNF271, ANXA4, NMI, UBE2L6, B2 M, HLA-F, PSMB9, TAP1, PSME2, IFI16, IFI27, ARHGAP9, RABGAP1L, TNK1, DEF6, BTN3A3, RPS6KA1, CD24, PARP10, APOL3, STAT, ANKRD10, CKB, H2AFZ, PSMB9, RARRES3, RGS10, TUBB, NOL3, CD7,RNAsHumanUpregulated in HCV related non-HCC than normal control (With 3-fold change) DiagnosticHCV related non-HCC v/s normal control p < 0.01Tissue19821982
2502CAPG, OCC-1, EED, RPLP0, RPLP0P2, AP1S2, RRAGD, PFDN4, CCDC104, C7orf28B, PSIP1, LPCAT1, FSCN3, RAB24, ZNF446, SEC11B, ZNF586, SCNM1, SF3A1, RUFY1, TRIM55, GOLGA4, GPATCH4, THOP1, TUBB2C, PHLDB3, FAM104A, FASTK, EIF2AK4, ZFP41, PRKRIP1, DSTN, PHIP, NUCKS1, TNRC8, CCDC132, EPRS, HIST1H4C, CDCA8,RNAsHumanUpregulated in HCV related HCC than HCV related non-HCC (With 3-fold change) DiagnosticHCV related HCC v/s HCV related non-HCC p < 0.01Tissue19821982
2503Fibronectin, Tubulin-alpha-1 subunit, Matrix metalloproteinase 14, osteonectin SPARC, RAD23A, Ubiquitin-conjugating enzyme E2, Neutrophil-gelatinase associated lipocalin precursor lipocalin 2, TRAM protein, ADP/ATP carrier protein, High mobility group protein, Insulin stimulated protein kinase 1, TrRNAsHumanDiffrenetially expressed in HCC v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue11973655
2504CDC28 protein kinase2, CDC27HS protein, Integrin beta 4, Desmoplakin 1/2, Procollagen C proteinase, platelet derived growth factor, cytidine deaminase, aminoacyalse1, Betaine homocysteine S-methyltransferase, methylenetetrahydrofolate dehydrogease, metalloproteinase inhibitor1, aldehyde oxidase, metRNAsHumanDiffrenetially expressed in HCV and HBV associated HCC v/s non-tumor DiagnosticHCV and HBV associated HCC v/s non-tumor p < 0.01Tissue11973655
2505Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated proteiRNAsHumanDiffrenetially expressed in cirrhotic v/s non-cirrhotic Diagnosticcirrhotic v/s non-cirrhotic p < 0.01Tissue11973655
2506Zinc finger protein, integrin alpha 6, hepatoma derived growth factor, TGF beta induced, Macrophage inhibitory cytokine 1, lymphocyte antigen, aldehyde oxidase, c-myc purine binding transcription factor puf, plasminogen, vitronectin, hemoglobin alpha subunit, cytosolic superoxide dismutase, methylenRNAsHumanDiffrenetially expressed in moderately differentiated HCC v/s poorly differentiated HCC Diagnosticmoderately differentiated HCC v/s poorly differentiated HCC p < 0.01Tissue11973655
2507SGCERNAsHumanUpregulated in HCC than non-tumor (with > 3 fold change) DiagnosticHCC v/s non-tumor p < 0.05Cell line, Tissue19171046
2508PEG10RNAsHumanUpregulated in HCC than non-tumor (with > 3 fold change) DiagnosticHCC v/s non-tumor p < 0.05Cell line, Tissue19171046
2509CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1RNAsHumanUpregulated in HCC than non-tumor (with > 3 fold change) DiagnosticHCC v/s non-tumor p < 0.05Cell line, Tissue19171046
2522BIC, CPNE1, RBPMS, RFC4, RPSA, TOP2ARNAsHumanUpregulated in dedifferentiated HCC (with fold change > 2.6) Diagnosticmoderately and well differentiated HCC v/s low-differentiated HCC FDR < 2%.Tissue18820673

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