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The total number entries retrieved from this search are 26
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2020AFP, AFP-L3, PIVKA-II, and UltrasoundProtein + TechniqueHumanNA DiagnosticNormal vs cancer NASerum28757516
2041AFPProtein HumanNA Diagnostic and PrognosticHCC vs CHB (Chronic hepatitis B); significantly associated with tumor node-metastasis (TNM) stage p < 0.001Serum28189396
2042AFP, Promoter methylation of HCCS1Protein and RNAHumanNA Diagnostic and PrognosticHCC vs CHB (Chronic hepatitis B); significantly associated with tumor node-metastasis (TNM) stage p < 0.05Serum28189396
2085Estrogen , Estradiol, AFPProtein + SteroidHumanDownregulated in liver cancer cell. DiagnosticNormal vs liver cancer p < 0.05Serum27060391
2087AFPProteinHumanDownregulated in liver cancer cell. DiagnosticNormal vs liver cancer p < 0.06Serum27060391
2103AFP-L3ProteinHumanUpregulated in AFP-negative HCC patients DiagnosticNormal vs HCC p < 0.01Tissue26770061
2105AFP-L3, GP73 (combined)ProteinHumanUpregulated in AFP-negative HCC patients DiagnosticNormal vs HCC p < 0.01Tissue26770061
2126AFP (at a cut-off of 20 ng/mL)ProteinHumanUpregulated level in HCC DiagnosticHCC with cirrhosis v/s HCV-associated cirrhosis p < 0.05Serum24095974
2159hnRNP K, AFPProteinHumanUpregulated in HCC DiagnosticEarly HCC vs Late HCC p < 0.01Serum22760167
2200AFP, (with cut off 0.9 of AFP in serum )ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2202AFP, BMK, (with cut off 1.25 of AFP in serum and 0.25 BMK in urine)ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2203AFP, BMK, (with cut off 1.20 of AFP in serum and 0.27 BMK in urine)ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2204AFP, BMK, (with cut off 0.90 of AFP in serum and 0.40 BMK in urine)ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2205AFP, BMK, (with cut off 1.65 of AFP in serum and 0.40 BMK n urine)ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2206AFP, BMK, (with cut off 0.9 of AFP in serum and 0.75 BMK in urine)ProteinHumanNA DiagnosticHCC v/s Non-HCC NASerum and Urine29152526
2219AFP, GGT, ALT, ASTProteinMale Sprague-Dawley ratsDownregulated Potential Prognostic *HCC v/s Normal/treated with AEA; associated with progression p < 0.0001Serum28900384
2220AFP, DCPProteinHumanAFP upregulated in HCC DiagnosticNormal vs HCC, Cirrhosis p < 0.001Serum19852963
2223AFP, (> =20 ng/mL)ProteinHumanAFP and DCP upregulated in HCC DiagnosticNormal vs HCC, Cirrhosis p < 0.001Serum19852963
2224AFP, (> =200 ng/mL)ProteinHumanAFP and DCP upregulated in HCC DiagnosticNormal vs HCC, Cirrhosis p < 0.001Serum19852963
2225AFP, DCP, ( DCP with a cut-off value of 86 mAU/mL and AFP with a cut-off value of 21 ng/mL)ProteinHumanAFP and DCP upregulated in HCC DiagnosticHCC v/s Normal p < 0.001Serum25382443
2226AFP, (cut-off value of 21 ng/mL)ProteinHumanAFP upregulated in HCC DiagnosticHCC v/s Normal p < 0.001Serum25382443
2228AFPProteinHumanAFP upregulated in HCC DiagnosticHCC v/s Non-HCC p < 0.001Serum29163838
2230AFP, DCP, (DCP >40 mAU/mL, AFP >20 ng/mL)ProteinHumanAFP and DCP upregulated in HCC DiagnosticHCC v/s Non-HCC p < 0.001Serum29163838
2319AFPProteinHumanUpegulated in HCC than non-tumor DiagnosticHCC v/s cirrhosis/healthy/non-tumor HCC p < 0.05Serum18281540
2320CSTB, AFPProteinHumanUpegulated in HCC than non-tumor DiagnosticHCC v/s cirrhosis/healthy/non-tumor HCC p < 0.05Serum18281540
2396AFPRNAsHumanUpregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456

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