| Detailed information |
|---|
| CancerLivER ID | 2230 |
| Biomarker | AFP, DCP, (DCP >40 mAU/mL, AFP >20 ng/mL) |
| Biomarker Name/Symbol (given in Publication) | Combination AFP and DCP (DCP >40 mAU/mL, AFP >20 ng/mL) |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Biomarker for diagnosis of HCC and validated on independent dataset |
| Experimental Condition | HCC v/s Non-HCC |
| Cancer type | Hepatocellular carcinoma |
| Regulation | AFP and DCP upregulated in HCC |
| Level of significance | p < 0.001 |
| Source | Serum |
| PMID | 29163838 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | 45 HCC patients (G 1), 43 liver cirrhosis patients (G 2), 42 patients with hepatitis virus infections (G 3), and 44 healthy individuals |
| Sensitivity | 84% |
| Specificity | 86% |
| Accuracy | NA |
| AUC | 0.89 |
| Disease | Human HCC |
| Year of Publication | 2017 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT03645655,NCT01360255,NCT01361061,NCT00513461,NCT03460080,NCT01277653,NCT03047603,NCT02272504, NCT02958163 |