CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2320
Detailed information
CancerLivER ID2320
Biomarker CSTB, AFP
Biomarker Name/Symbol (given in Publication) CSTB + AFP
BiomoleculeProtein
SubjectHuman
Degree of ValidityCSTB and AFP might be a potential marker for diagnosing HCC and validated on independent dataset
Experimental ConditionHCC v/s cirrhosis/healthy/non-tumor HCC
Cancer typeHepatocellular carcinoma
RegulationUpegulated in HCC than non-tumor
Level of significance p < 0.05
SourceSerum
PMID18281540
Type of BiomarkerDiagnostic
Pathway
CohortNormal healthy subjects (group 1, n = 52) and patients with noncirrhotic chronic hepatitis (group 2, n = 53), cirrhosis (group 3, n = 43), and HCC (group 4, n = 62); HCC cell lines, including HepG2, Hep3B, PLC/PRF/5, Huh7, and SK-HEP-1 cells, and immortalized epithelial cell lines, such as THLE-3 an
Sensitivity72.60%
Specificity78.10%
AccuracyNA
AUC0.824
DiseaseHCC v/s cirrhosis/healthy/non-tumor HCC
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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