| Detailed information |
|---|
| CancerLivER ID | 2223 |
| Biomarker | AFP, (> =20 ng/mL) |
| Biomarker Name/Symbol (given in Publication) | AFP (> =20 ng/mL) |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Biomarker for diagnosis of HCC and validated on independent dataset |
| Experimental Condition | Normal vs HCC, Cirrhosis |
| Cancer type | Hepatocellular carcinoma |
| Regulation | AFP and DCP upregulated in HCC |
| Level of significance | p < 0.001 |
| Source | Serum |
| PMID | 19852963 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | 1031 patients:39 HCC cases, 77 matched controls and 915 other non-HCC patients |
| Sensitivity | 61% |
| Specificity | 81% |
| Accuracy | NA |
| AUC | 0.79 |
| Disease | Human HCC |
| Year of Publication | 2010 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT00005629,NCT03132792,NCT00513461,NCT00093548,NCT01350167,NCT02435433,NCT02072356,NCT02582918,NCT02232490,NCT01128803,NCT02312817,NCT01849588,NCT03156582,NCT03533582,NCT03767764,NCT01078311,NCT03493763,NCT00980460,NCT00629421,NCT01392131,NCT0174764 |