| Detailed information |
|---|
| CancerLivER ID | 2220 |
| Biomarker | AFP, DCP |
| Biomarker Name/Symbol (given in Publication) | AFP and DCP |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Biomarker for diagnosis of HCC and validated on independent dataset |
| Experimental Condition | Normal vs HCC, Cirrhosis |
| Cancer type | Hepatocellular carcinoma |
| Regulation | AFP upregulated in HCC |
| Level of significance | p < 0.001 |
| Source | Serum |
| PMID | 19852963 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | 1031 patients:39 HCC cases, 77 matched controls and 915 other non-HCC patients |
| Sensitivity | 91% |
| Specificity | 74% |
| Accuracy | NA |
| AUC | 0.92 |
| Disease | Human HCC |
| Year of Publication | 2010 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT03645655,NCT01360255,NCT01361061,NCT00513461,NCT03460080,NCT01277653,NCT03047603,NCT02272504, NCT02958163 |