CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2228
Detailed information
CancerLivER ID2228
Biomarker AFP
Biomarker Name/Symbol (given in Publication)AFP
BiomoleculeProtein
SubjectHuman
Degree of ValidityBiomarker for diagnosis of HCC and validated on independent dataset
Experimental ConditionHCC v/s Non-HCC
Cancer typeHepatocellular carcinoma
RegulationAFP upregulated in HCC
Level of significance p < 0.001
SourceSerum
PMID29163838
Type of BiomarkerDiagnostic
PathwayNA
Cohort45 HCC patients (G 1), 43 liver cirrhosis patients (G 2), 42 patients with hepatitis virus infections (G 3), and 44 healthy individuals
Sensitivity73%
Specificity92%
AccuracyNA
AUC0.84
DiseaseHuman HCC
Year of Publication2017
Clinical trialYES
NCT No# (Clinical trial) NCT00005629,NCT03132792,NCT00513461,NCT00093548,NCT01350167,NCT02435433,NCT02072356,NCT02582918,NCT02232490,NCT01128803,NCT02312817,NCT01849588,NCT03156582,NCT03533582,NCT03767764,NCT01078311,NCT03493763,NCT00980460,NCT00629421,NCT01392131,NCT0174764

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