Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_0090	Not Determined Click for more detail	herpes simplex virus (virus)	NA	NA	Others	Natural	Immunostimulant	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	NA	Q9QUN7.fasta	Q9QUN7	784	NA	NA	11062499	2000	Pubchem Assay
PRRID_0090	Not Determined Click for more detail	herpes simplex virus (virus)	NA	NA	Others	Natural	Immunostimulant	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	NA	Q9QUN7.fasta	Q9QUN7	784	NA	NA	11062499	2000	Pubchem Assay
PRRID_0096	viral hemagglutinin (HA) Click for more detail	Influenza A (virus)	MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI	566	NA	Natural	Immunostimulant	NA	NA	Mice (Murine)	Macrophages	NA	NA	NA	NA	NA	ELISA	0	2000	NA
PRRID_0096	viral hemagglutinin (HA) Click for more detail	Influenza A (virus)	MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEEMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI	566	NA	Natural	Immunostimulant	NA	NA	Mice (Murine)	Macrophages	NA	NA	NA	NA	NA	ELISA	0	2000	NA
PRRID_0099	dsRNA Click for more detail	Type I Lang mammalian reovirus (virus)	NA	NA	Nucleic Acid	Natural	It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12.	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	(HEK293 t cells)	NA	O15455.fasta	O15455	904	IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens.	EMSA	11607032	2001	Pubchem Assay
PRRID_0099	dsRNA Click for more detail	Type I Lang mammalian reovirus (virus)	NA	NA	Nucleic Acid	Natural	It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12.	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	(HEK293 t cells)	NA	O15455.fasta	O15455	904	IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens.	EMSA	11607032	2001	Pubchem Assay
PRRID_0130	Hemagglutinin Click for more detail	virus (measles virus)	MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLGRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKRSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYLEQPVSNDLSNCMVALGELKLAALCHGEDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDNRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPYLFNVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMEGMGVSCTVTREDGTNRR	617	Glycoprotein	Natural	Immunostimulant	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice (Murine)	NA	NA	Q9QUN7.fasta	Q9QUN7	784	NA	ELISA	12163593	2002	Pubchem Assay
PRRID_0130	Hemagglutinin Click for more detail	virus (measles virus)	MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLGRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKRSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYLEQPVSNDLSNCMVALGELKLAALCHGEDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDNRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPYLFNVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMEGMGVSCTVTREDGTNRR	617	Glycoprotein	Natural	Immunostimulant	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice (Murine)	NA	NA	Q9QUN7.fasta	Q9QUN7	784	NA	ELISA	12163593	2002	Pubchem Assay
PRRID_0169	HCV E1 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	triggers immune responses	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	C type Lectin (CTL/CLR)	Human	dendritic cells	NA	NA	NA	NA	promote HIV and Hepatitis C virus to infect T-cell from dendritic cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0169	HCV E1 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	triggers immune responses	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	C type Lectin (CTL/CLR)	Human	dendritic cells	NA	NA	NA	NA	promote HIV and Hepatitis C virus to infect T-cell from dendritic cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0170	HCV E1 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	triggers immune responses	DC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)	C type Lectin (CTL/CLR)	Human	endothelial cell populations, including hepatic sinusoidal endothelial cells	NA	NA	NA	NA	functions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0170	HCV E1 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	triggers immune responses	DC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)	C type Lectin (CTL/CLR)	Human	endothelial cell populations, including hepatic sinusoidal endothelial cells	NA	NA	NA	NA	functions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0171	HCV E2 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	elicit innate immune response	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	C type Lectin (CTL/CLR)	Human	dendritic cells	NA	NA	NA	NA	promote HIV and Hepatitis C virus to infect T-cell from dendritic cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0171	HCV E2 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	elicit innate immune response	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	C type Lectin (CTL/CLR)	Human	dendritic cells	NA	NA	NA	NA	promote HIV and Hepatitis C virus to infect T-cell from dendritic cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0172	HCV E2 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	elicit innate immune response	DC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)	C type Lectin (CTL/CLR)	Human	endothelial cell populations, including hepatic sinusoidal endothelial cells	NA	NA	NA	NA	functions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0172	HCV E2 glycoproteins Click for more detail	Hepatitis C Virus (virus)	DAWDMMMNWSPTTALVVSQLLRIPQAVVDIVAGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTQTTGRVAARNAHGFTSLFSPGASQNLQLINTNGSWHINR	106	Glycoprotein	Natural	elicit innate immune response	DC-SIGNR (Dendritic cell-specific ICAM-3-grabbing nonintegrin related protein)	C type Lectin (CTL/CLR)	Human	endothelial cell populations, including hepatic sinusoidal endothelial cells	NA	NA	NA	NA	functions as an attachment factor for HIV and is expressed on liver sinusoidal endothelial cells	enzyme-linked immunosorbent assay	12634366	2003	NA
PRRID_0197	Envelope protein Click for more detail	virus (Mouse Mammary Tumor Virus)	NA	NA	Protein	Natural	activation of the NF-Œ∫B pro-inflammatory cascade	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	NA	NA	Q9QUK6.fasta	Q9QUK6	835	NA	NA	14694089	2004	Pubchem Assay
PRRID_0197	Envelope protein Click for more detail	virus (Mouse Mammary Tumor Virus)	NA	NA	Protein	Natural	activation of the NF-Œ∫B pro-inflammatory cascade	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	NA	NA	Q9QUK6.fasta	Q9QUK6	835	NA	NA	14694089	2004	Pubchem Assay
PRRID_0201	glycoprotein GP Click for more detail	virus (Marburg virus)	MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG	681	Glycoprotein	Natural	Immunostimulant	DC-SIGN	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0201	glycoprotein GP Click for more detail	virus (Marburg virus)	MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG	681	Glycoprotein	Natural	Immunostimulant	DC-SIGN	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0202	glycoprotein GP Click for more detail	virus (Marburg virus)	MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG	681	Glycoprotein	Natural	Immunostimulant	DC-SIGNR	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0202	glycoprotein GP Click for more detail	virus (Marburg virus)	MKTTCFLISLILIQGTKNLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPPPLPTARPEIKLTSTPTDATKLNTTDPSSDDEDLATSGSGSGEREPHTTSDAVTKQGLSSTMPPTPSPQPSTPQQGGNNTNHSQDAVTELDKNNTTAQPSMPPHNTTTISTNNTSKHNFSTLSAPLQNTTNDNTQSTITENEQTSAPSITTLPPTGNPTTAKSTSSKKGPATTAPNTTNEHFTSPPPTPSSTAQHLVYFRRKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAVLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSKNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG	681	Glycoprotein	Natural	Immunostimulant	DC-SIGNR	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0205	Influenza virus Click for more detail	Influenza A (virus)	NA	NA	Whole cell	Natural	It leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1.	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Alveolar and bronchial epithelial cells	NA	O15455.fasta	O15455	904	It causes pulmonary inflammation.	ELISA	15579900	2004	Pubchem Assay
PRRID_0205	Influenza virus Click for more detail	Influenza A (virus)	NA	NA	Whole cell	Natural	It leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1.	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Alveolar and bronchial epithelial cells	NA	O15455.fasta	O15455	904	It causes pulmonary inflammation.	ELISA	15579900	2004	Pubchem Assay
PRRID_0209	S protein Click for more detail	virus (SARS-CoV)	MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEI	1255	Glycoprotein	Natural	Immunostimulant	DC-SIGN	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0209	S protein Click for more detail	virus (SARS-CoV)	MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEI	1255	Glycoprotein	Natural	Immunostimulant	DC-SIGN	C type Lectin (CTL/CLR)	Host	NA	NA	NA	NA	NA	DCs are good candidates to modulate the immune system‚Äôs activity in infection, cancer, and autoimmunity	soluble S-based binding assay	15479853	2004	NA
PRRID_0252	dsDNA Click for more detail	Adenovirus(virus)	NA	NA	Nucleic Acid	Natural	Adenovirus induces the production of high levels of type I interferons (IFNs),is mediated by TLR9 in a MyD88-dependent manner.	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Mice	Plasmacytoid dendritic cells	NA	Q9NR96.fasta	Q9NR96	1032	This leads to the inflammatory response.	ELISA	17229689	2007	Pubchem Assay
PRRID_0252	dsDNA Click for more detail	Adenovirus(virus)	NA	NA	Nucleic Acid	Natural	Adenovirus induces the production of high levels of type I interferons (IFNs),is mediated by TLR9 in a MyD88-dependent manner.	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Mice	Plasmacytoid dendritic cells	NA	Q9NR96.fasta	Q9NR96	1032	This leads to the inflammatory response.	ELISA	17229689	2007	Pubchem Assay
PRRID_0293	Hantaan virus (HTNV) Click for more detail	Hantaan virus (HTNV) (Virus)	NA	NA	Whole organism	Natural	HTNV infection induces IFN-Œ≤, IL-6 and TNF-Œ± expression.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Endothelial vein cells (EVC-304)	LRR	O00206.fasta	O00206	839	TLR4 is a potential factor in HFRS pathogenesis.	ELISA	18707748	2008	Pubchem Assay
PRRID_0293	Hantaan virus (HTNV) Click for more detail	Hantaan virus (HTNV) (Virus)	NA	NA	Whole organism	Natural	HTNV infection induces IFN-Œ≤, IL-6 and TNF-Œ± expression.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Endothelial vein cells (EVC-304)	LRR	O00206.fasta	O00206	839	TLR4 is a potential factor in HFRS pathogenesis.	ELISA	18707748	2008	Pubchem Assay
PRRID_0354	Viral RNA Click for more detail	Murine norovirus-1 (virus)	NA	NA	Nucleic Acid	Natural	Upon stimulation, it leads to the production of IFN-alpha, IL-6, MCP-1, TNFalpha and IFN-beta.	MDA5	Rig-like receptor (RLR)	Mice	Bone marrow-derived DC	NA	Q8R5F7.fasta	Q8R5F7	1025	MDA5 limits MNV-1 replication.	ELISA	18636103	2008	Pubchem Assay
PRRID_0354	Viral RNA Click for more detail	Murine norovirus-1 (virus)	NA	NA	Nucleic Acid	Natural	Upon stimulation, it leads to the production of IFN-alpha, IL-6, MCP-1, TNFalpha and IFN-beta.	MDA5	Rig-like receptor (RLR)	Mice	Bone marrow-derived DC	NA	Q8R5F7.fasta	Q8R5F7	1025	MDA5 limits MNV-1 replication.	ELISA	18636103	2008	Pubchem Assay
PRRID_0367	Grass carp reovirus Click for more detail	Grass carp reovirus (virus)	NA	NA	Whole organism	Natural	Toll-like receptor 4 signaling pathway is trigger by grass carp reovirus.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Gobiocypris rarus	Gill, Heart, Intestine, Kidney, Liver, Muscle and Spleen tissues	LRR	NA	NA	NA	This is responsible for the recognition of the virus and elicit the immune response against it.	NA	19264133	2009	NA
PRRID_0367	Grass carp reovirus Click for more detail	Grass carp reovirus (virus)	NA	NA	Whole organism	Natural	Toll-like receptor 4 signaling pathway is trigger by grass carp reovirus.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Gobiocypris rarus	Gill, Heart, Intestine, Kidney, Liver, Muscle and Spleen tissues	LRR	NA	NA	NA	This is responsible for the recognition of the virus and elicit the immune response against it.	NA	19264133	2009	NA
PRRID_0400	Viral Genome Click for more detail	Rabies virus (virus)	NA	NA	Nucleic Acid	Natural	Rabies genome is a potent activator of TLR3	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Neuronal cells	NA	O15455.fasta	O15455	904	TLR3 is involved in the spatial arrangement of rabies virus‚Äìinduced NBs and viral replication.	NA	19247444	2009	Pubchem Assay
PRRID_0400	Viral Genome Click for more detail	Rabies virus (virus)	NA	NA	Nucleic Acid	Natural	Rabies genome is a potent activator of TLR3	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Neuronal cells	NA	O15455.fasta	O15455	904	TLR3 is involved in the spatial arrangement of rabies virus‚Äìinduced NBs and viral replication.	NA	19247444	2009	Pubchem Assay
PRRID_0404	A46R Click for more detail	Vaccinia(virus)	MAFDISVNASKTINALVYFSTQQNKLVIRNEVNDTHYTVEFDRDKVVDTFISYNRHNDTIEIRGVLPEETNIGCAVNTPVSMTYLYNKYSFKLILAEYIRHRNTISGNIYSALMTLDDLAIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVALSSLVSKHWELTNKKYRCMALANIYLIVFQYLSYLDYDTIYVSIYAGTLRA	214	Protein	Natural	Suppress NF-Œ∫B activation (Bind to MyD88, TRAM, and TRIF)	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0404	A46R Click for more detail	Vaccinia(virus)	MAFDISVNASKTINALVYFSTQQNKLVIRNEVNDTHYTVEFDRDKVVDTFISYNRHNDTIEIRGVLPEETNIGCAVNTPVSMTYLYNKYSFKLILAEYIRHRNTISGNIYSALMTLDDLAIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVALSSLVSKHWELTNKKYRCMALANIYLIVFQYLSYLDYDTIYVSIYAGTLRA	214	Protein	Natural	Suppress NF-Œ∫B activation (Bind to MyD88, TRAM, and TRIF)	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0405	A52R Click for more detail	Vaccinia(virus)	MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMSTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS	190	Protein	Natural	Suppress NF-Œ∫B activation (Bind to IRAK2) and	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0405	A52R Click for more detail	Vaccinia(virus)	MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMSTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS	190	Protein	Natural	Suppress NF-Œ∫B activation (Bind to IRAK2) and	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0406	A52R Click for more detail	Vaccinia(virus)	MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMSTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS	190	Protein	Natural	Activate p38 MAPK and JNK (Bind to TRAF6)	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Induce IL-10 production	NA	20672047	2010	NA
PRRID_0406	A52R Click for more detail	Vaccinia(virus)	MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMSTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS	190	Protein	Natural	Activate p38 MAPK and JNK (Bind to TRAF6)	Toll-like receptor 1/2 (TLR1/2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Induce IL-10 production	NA	20672047	2010	NA
PRRID_0427	Bform dsDNA Click for more detail	HCMV (virus)	NA	NA	Nucleic Acid	Natural	It leads to the activation of IRF3, which participate in the induction of IFN-Œ≤ expression	ZBP-1 or DAI	DNA Receptor	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0427	Bform dsDNA Click for more detail	HCMV (virus)	NA	NA	Nucleic Acid	Natural	It leads to the activation of IRF3, which participate in the induction of IFN-Œ≤ expression	ZBP-1 or DAI	DNA Receptor	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0429	BV-nucleic acid Click for more detail	Baculovirus(virus)	NA	NA	Nucleic Acid	Natural	It leads to increased expression of cytokine IL-12 p40	Toll-like receptor 21 (TLR21)	Toll-like receptor (TLR)	Chicken	Macrophage-like cell line (HD11)	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	This results into the inflammatory response, which leads to clearance of pathogen	NA	20471186	2010	NA
PRRID_0429	BV-nucleic acid Click for more detail	Baculovirus(virus)	NA	NA	Nucleic Acid	Natural	It leads to increased expression of cytokine IL-12 p40	Toll-like receptor 21 (TLR21)	Toll-like receptor (TLR)	Chicken	Macrophage-like cell line (HD11)	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	This results into the inflammatory response, which leads to clearance of pathogen	NA	20471186	2010	NA
PRRID_0441	core protein Click for more detail	Hepatitis C Virus (virus)	MSTNPKPQRKTKRNTNRRPMDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRTEGRSWAQPGYPWPLYGNEGCGWAGWLLSPRGSRXSWGPNDPRXRSRNLGKVIDTLTCGFADLMGYIPLVGAPVGGVARALAHGVRAVEDGINYATGNLPGCSFSIFLLALLSCLTVPTSAVNYRNASGIYHITNDCPNASIVYETENHILHLPGCVPCVRTGNQSRCWVALTPTVASPYAGAPLEPLRRHVDLMVGAATMCSALYIGDLCGGLFLVGQMFTFQPRRHWTTQDCNCSIYTGHITGHRMA	319	Protein	Natural	Induce cytokines responses through nuclear translocation of nuclear factor-kB (NF-kB) subunits	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Antigen presenting cells	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	It reduces the IL-6 production in these cells	NA	20677943	2010	Pubchem Assay
PRRID_0441	core protein Click for more detail	Hepatitis C Virus (virus)	MSTNPKPQRKTKRNTNRRPMDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRTEGRSWAQPGYPWPLYGNEGCGWAGWLLSPRGSRXSWGPNDPRXRSRNLGKVIDTLTCGFADLMGYIPLVGAPVGGVARALAHGVRAVEDGINYATGNLPGCSFSIFLLALLSCLTVPTSAVNYRNASGIYHITNDCPNASIVYETENHILHLPGCVPCVRTGNQSRCWVALTPTVASPYAGAPLEPLRRHVDLMVGAATMCSALYIGDLCGGLFLVGQMFTFQPRRHWTTQDCNCSIYTGHITGHRMA	319	Protein	Natural	Induce cytokines responses through nuclear translocation of nuclear factor-kB (NF-kB) subunits	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Antigen presenting cells	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	It reduces the IL-6 production in these cells	NA	20677943	2010	Pubchem Assay
PRRID_0442	core protein Click for more detail	Hepatitis C Virus (virus)	MSTNPKPQRKTKRNTNRRPMDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRTEGRSWAQPGYPWPLYGNEGCGWAGWLLSPRGSRXSWGPNDPRXRSRNLGKVIDTLTCGFADLMGYIPLVGAPVGGVARALAHGVRAVEDGINYATGNLPGCSFSIFLLALLSCLTVPTSAVNYRNASGIYHITNDCPNASIVYETENHILHLPGCVPCVRTGNQSRCWVALTPTVASPYAGAPLEPLRRHVDLMVGAATMCSALYIGDLCGGLFLVGQMFTFQPRRHWTTQDCNCSIYTGHITGHRMA	319	Protein	Natural	Activate MAP kinase pathway, NF-Œ∫B, and AP-1	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	monocytes and Kupffer cells	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	Dysfunction of pDCs by enhanced production of IL-10 and TNF- Œ±	NA	20672047	2010	Pubchem Assay
PRRID_0442	core protein Click for more detail	Hepatitis C Virus (virus)	MSTNPKPQRKTKRNTNRRPMDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRTEGRSWAQPGYPWPLYGNEGCGWAGWLLSPRGSRXSWGPNDPRXRSRNLGKVIDTLTCGFADLMGYIPLVGAPVGGVARALAHGVRAVEDGINYATGNLPGCSFSIFLLALLSCLTVPTSAVNYRNASGIYHITNDCPNASIVYETENHILHLPGCVPCVRTGNQSRCWVALTPTVASPYAGAPLEPLRRHVDLMVGAATMCSALYIGDLCGGLFLVGQMFTFQPRRHWTTQDCNCSIYTGHITGHRMA	319	Protein	Natural	Activate MAP kinase pathway, NF-Œ∫B, and AP-1	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	monocytes and Kupffer cells	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	Dysfunction of pDCs by enhanced production of IL-10 and TNF- Œ±	NA	20672047	2010	Pubchem Assay
PRRID_0446	CpG motif Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It recognize and raise the inflammatory response	NA	20713890	2010	Pubchem Assay
PRRID_0446	CpG motif Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It recognize and raise the inflammatory response	NA	20713890	2010	Pubchem Assay
PRRID_0447	CpG motif Click for more detail	HSV-2 (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 10 (TLR10)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	Q9BXR5.fasta	Q9BXR5	811	It recognize and raise the inflammatory response	NA	20713890	2010	Pubchem Assay
PRRID_0447	CpG motif Click for more detail	HSV-2 (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 10 (TLR10)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	Q9BXR5.fasta	Q9BXR5	811	It recognize and raise the inflammatory response	NA	20713890	2010	Pubchem Assay
PRRID_0448	CpG motif Click for more detail	murine CMV (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 10 (TLR10)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It recognize and raise the inflammatory response	NA	20713890	2010	NA
PRRID_0448	CpG motif Click for more detail	murine CMV (virus)	NA	NA	Nucleic Acid	Natural	It's binding leads to the release of the arra of cytokines	Toll-like receptor 10 (TLR10)	Toll-like receptor (TLR)	Human	DCs	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	It recognize and raise the inflammatory response	NA	20713890	2010	NA
PRRID_0465	DNA Click for more detail	EBV(virus)	NA	NA	Nucleic Acid	Natural	It leads to the release of monocyte chemoattractant protein-1 (MCP-1) and to an increase of several cytokine mRNA levels	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Monocytes	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It provides antiviral immunity	NA	20713890	2010	Pubchem Assay
PRRID_0465	DNA Click for more detail	EBV(virus)	NA	NA	Nucleic Acid	Natural	It leads to the release of monocyte chemoattractant protein-1 (MCP-1) and to an increase of several cytokine mRNA levels	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Monocytes	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It provides antiviral immunity	NA	20713890	2010	Pubchem Assay
PRRID_0466	DNA Click for more detail	murine CMV (virus)	GTAATCTAACCACTTGTGTGTGTGTGTGTGTGTGTCGAGTCGTGTCGTCTGTACATTTGAGTCGTGCTGTCCGCACATTTTATTTATCTTTGTTCAGTGTGTTAGATTTCCCGAGGCATGGCTTTCCAAGGTACCAGTAGGACTTTAACTCAACAGTCCTCAGCGGCTACGTCTGACGATCTTCAAAAGATATTATTTAGCCCTGAAGCCATTAAGAAAATGGCTACTGAGTGTGACCTAGGCCGGCATCACTGGATGCGCGCTGATAATGCTATTTCAGTCCGGCCCCTCGTTCCCGAAGTAACCCACGGTCGTATTGCTTCTTTCTTTAAGTCTGGATATGATGTTGGTGAATTATGCTCAAAAGGATATATGAGCGTCCCTCAAGTGTTATGTGCTGTTACTCGAACAGTTTCCACTGATGCTGAAGGGTCCCTGAGAATTTACTTAGCTGATCTAGGCGACAAGGAGTTATCTCCTATAGACGGGCAGTGCGTTTCGTTACATAACCATGATCTTCCCGCTTTGGTGTCTTTCCAACCGACGTATGATTGTCCTATGGAAACAGTTGGGAATCGTAAGCGGTGTTTTGCTGTTGTTATCGAAAGACATGGTTACATTGGGTATACCGGTACCACAGCTAGCGTGTGTAGTAATTGGCAAGCAAGGTTTTCTTCTAAGAATAACAACTACACTCATATCGCAGCTGGGAAGACTCTAGTACTACCTTTCAACAGATTAGCCGAGCAAACAAAACCGTCAGCTGTCGCTCGCCTGTTGAAATCGCAATTGAACAACATTGAATCTTCGCAATATCTGTTAACGAACGCGAAGATTAATCAAAATGCGCGTAGTGAGTCCGAGGAATTAAATGTTGAGAGCCCTCCCGCCGCAATCGGGAGTTCTTCCGCGTCCCGCTCCGAAGCCTTCAGACCGCAGGTGGTTAACGGTCTTTAGCACTTTGGTGCGTATTAGTATATAAGTATTTGTGAGTCTGTAC	2213	Nucleic Acid	Natural	It leads to the release of monocyte chemoattractant protein-1 (MCP-1) and to an increase of several cytokine mRNA levels	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	PDCs	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	It provides antiviral immunity	NA	20713890	2010	Pubchem Assay
PRRID_0466	DNA Click for more detail	murine CMV (virus)	GTAATCTAACCACTTGTGTGTGTGTGTGTGTGTGTCGAGTCGTGTCGTCTGTACATTTGAGTCGTGCTGTCCGCACATTTTATTTATCTTTGTTCAGTGTGTTAGATTTCCCGAGGCATGGCTTTCCAAGGTACCAGTAGGACTTTAACTCAACAGTCCTCAGCGGCTACGTCTGACGATCTTCAAAAGATATTATTTAGCCCTGAAGCCATTAAGAAAATGGCTACTGAGTGTGACCTAGGCCGGCATCACTGGATGCGCGCTGATAATGCTATTTCAGTCCGGCCCCTCGTTCCCGAAGTAACCCACGGTCGTATTGCTTCTTTCTTTAAGTCTGGATATGATGTTGGTGAATTATGCTCAAAAGGATATATGAGCGTCCCTCAAGTGTTATGTGCTGTTACTCGAACAGTTTCCACTGATGCTGAAGGGTCCCTGAGAATTTACTTAGCTGATCTAGGCGACAAGGAGTTATCTCCTATAGACGGGCAGTGCGTTTCGTTACATAACCATGATCTTCCCGCTTTGGTGTCTTTCCAACCGACGTATGATTGTCCTATGGAAACAGTTGGGAATCGTAAGCGGTGTTTTGCTGTTGTTATCGAAAGACATGGTTACATTGGGTATACCGGTACCACAGCTAGCGTGTGTAGTAATTGGCAAGCAAGGTTTTCTTCTAAGAATAACAACTACACTCATATCGCAGCTGGGAAGACTCTAGTACTACCTTTCAACAGATTAGCCGAGCAAACAAAACCGTCAGCTGTCGCTCGCCTGTTGAAATCGCAATTGAACAACATTGAATCTTCGCAATATCTGTTAACGAACGCGAAGATTAATCAAAATGCGCGTAGTGAGTCCGAGGAATTAAATGTTGAGAGCCCTCCCGCCGCAATCGGGAGTTCTTCCGCGTCCCGCTCCGAAGCCTTCAGACCGCAGGTGGTTAACGGTCTTTAGCACTTTGGTGCGTATTAGTATATAAGTATTTGTGAGTCTGTAC	2213	Nucleic Acid	Natural	It leads to the release of monocyte chemoattractant protein-1 (MCP-1) and to an increase of several cytokine mRNA levels	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	PDCs	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	It provides antiviral immunity	NA	20713890	2010	Pubchem Assay
PRRID_0467	DNA Click for more detail	Vaccinia(virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	Leucine-rich Repeat (LRR) Domain	Q9QUN7.fasta	Q9QUN7	784	It has the role in the inflammation.	NA	20709294	2010	Pubchem Assay
PRRID_0467	DNA Click for more detail	Vaccinia(virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Mice	NA	Leucine-rich Repeat (LRR) Domain	Q9QUN7.fasta	Q9QUN7	784	It has the role in the inflammation.	NA	20709294	2010	Pubchem Assay
PRRID_0476	ds RNA with 5'-triphosphate end Click for more detail	Sendai (virus)	NA	NA	Nucleic Acid	Natural	It's binding activate type I IFN response	RIG-1	Rig-like receptor (RLR)	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0476	ds RNA with 5'-triphosphate end Click for more detail	Sendai (virus)	NA	NA	Nucleic Acid	Natural	It's binding activate type I IFN response	RIG-1	Rig-like receptor (RLR)	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0477	ds RNA with 5'-triphosphate end Click for more detail	Influenza A (virus)	NA	NA	Nucleic Acid	Natural	It's binding activate type I IFN response	RIG-1	Rig-like receptor (RLR)	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0477	ds RNA with 5'-triphosphate end Click for more detail	Influenza A (virus)	NA	NA	Nucleic Acid	Natural	It's binding activate type I IFN response	RIG-1	Rig-like receptor (RLR)	NA	NA	NA	NA	NA	NA	It results into the anti-viral response by the immune system of host	NA	20620129	2010	NA
PRRID_0478	dsDNA Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	it mediate IFNs and cytokine production	ZBP-1 or DAI	DNA receptor	Mice (Murine)	Cytoplasm	NA	Q9QY24.fasta	Q9QY24	411	It has the role in the inflammation.	NA	20739519	2010	Pubchem Assay
PRRID_0478	dsDNA Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	it mediate IFNs and cytokine production	ZBP-1 or DAI	DNA receptor	Mice (Murine)	Cytoplasm	NA	Q9QY24.fasta	Q9QY24	411	It has the role in the inflammation.	NA	20739519	2010	Pubchem Assay
PRRID_0479	dsDNA Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	It mediate IFNs and cytokine production	RNA Pol-III	DNA receptor	Mice (Murine)	Cytoplasm	NA	Q9D483.fasta	Q9D483	533	It has the role in the inflammation.	NA	20739519	2010	Pubchem Assay
PRRID_0479	dsDNA Click for more detail	HSV-1 (virus)	NA	NA	Nucleic Acid	Natural	It mediate IFNs and cytokine production	RNA Pol-III	DNA receptor	Mice (Murine)	Cytoplasm	NA	Q9D483.fasta	Q9D483	533	It has the role in the inflammation.	NA	20739519	2010	Pubchem Assay
PRRID_0481	dsDNA Click for more detail	Ectromelia(virus)	NA	NA	Nucleic Acid	Natural	It is necessary for IL-6 production	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Mice	dendritic cells	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leads to the inflammation of the cell	NA	20709294	2010	Pubchem Assay
PRRID_0481	dsDNA Click for more detail	Ectromelia(virus)	NA	NA	Nucleic Acid	Natural	It is necessary for IL-6 production	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Mice	dendritic cells	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leads to the inflammation of the cell	NA	20709294	2010	Pubchem Assay
PRRID_0482	dsDNA Click for more detail	Rabies virus (virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	neurons	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	NA	NA	20706642	2010	Pubchem Assay
PRRID_0482	dsDNA Click for more detail	Rabies virus (virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	neurons	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	NA	NA	20706642	2010	Pubchem Assay
PRRID_0483	dsDNA Click for more detail	herpes simplex virus (virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	neurons	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	NA	NA	20706642	2010	Pubchem Assay
PRRID_0483	dsDNA Click for more detail	herpes simplex virus (virus)	NA	NA	Nucleic Acid	Natural	NA	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	neurons	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	NA	NA	20706642	2010	Pubchem Assay
PRRID_0484	dsDNA Click for more detail	vaccinia virus and murine cytomegalovirus (virus)	NA	NA	Nucleic Acid	Natural	It induces the caspase-1 activation and controls the catalytic cleavage of pro-form of the cytokine IL-1B	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	NA	O00206.fasta	O00206	839	It is involved in caspase-1-mediated maturation of IL-1Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0484	dsDNA Click for more detail	vaccinia virus and murine cytomegalovirus (virus)	NA	NA	Nucleic Acid	Natural	It induces the caspase-1 activation and controls the catalytic cleavage of pro-form of the cytokine IL-1B	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	NA	O00206.fasta	O00206	839	It is involved in caspase-1-mediated maturation of IL-1Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0486	dsDNA Click for more detail	Vesicular stomatitis (virus)	NA	NA	Nucleic Acid	Natural	LRRFIP1 bound Œ≤-catenin and promoted the activation of Œ≤-catenin, which subsequently bound IRF3 which leads to the production of IFN-Œ≤	LRRFIP2	Cytosolic receptor	RAW264.7 cells	cytoplasm	NA	Q91WK0.fasta	Q91WK0	415	It induce the production of type I interferon is important for pathogen elimination.	ELISA	20453844	2010	Pubchem Assay
PRRID_0486	dsDNA Click for more detail	Vesicular stomatitis (virus)	NA	NA	Nucleic Acid	Natural	LRRFIP1 bound Œ≤-catenin and promoted the activation of Œ≤-catenin, which subsequently bound IRF3 which leads to the production of IFN-Œ≤	LRRFIP2	Cytosolic receptor	RAW264.7 cells	cytoplasm	NA	Q91WK0.fasta	Q91WK0	415	It induce the production of type I interferon is important for pathogen elimination.	ELISA	20453844	2010	Pubchem Assay
PRRID_0487	dsDNA Click for more detail	Vaccinia(virus)	NA	NA	Nucleic Acid	Natural	It induces the activation of NF-	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Mice (Murine)	HEK293 cells, PDCs	LRR	P58682.fasta	P58682	1032	TLR8-MyD88-dependent pDC activation played a critical role in innate immune control of VV infection.	ELISA	20308556	2010	Pubchem Assay
PRRID_0487	dsDNA Click for more detail	Vaccinia(virus)	NA	NA	Nucleic Acid	Natural	It induces the activation of NF-	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Mice (Murine)	HEK293 cells, PDCs	LRR	P58682.fasta	P58682	1032	TLR8-MyD88-dependent pDC activation played a critical role in innate immune control of VV infection.	ELISA	20308556	2010	Pubchem Assay
PRRID_0488	dsDNA viruses Click for more detail	HSV, MCMV (virus)	NA	NA	Nucleic Acid	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD91	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Endosomes	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory and IFN-‚ç∫	NA	20620129	2010	Pubchem Assay
PRRID_0488	dsDNA viruses Click for more detail	HSV, MCMV (virus)	NA	NA	Nucleic Acid	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD91	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Endosomes	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	It leadsto the secretion of the proinfalmmatory and IFN-‚ç∫	NA	20620129	2010	Pubchem Assay
PRRID_0489	dsRNA virus Click for more detail	RSV (virus)	NA	NA	Nucleic Acid	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins TRIF	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Endosomes	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	it lead to the secretion of IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0489	dsRNA virus Click for more detail	RSV (virus)	NA	NA	Nucleic Acid	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins TRIF	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Endosomes	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	it lead to the secretion of IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0490	EBV DNA Click for more detail	Epstein-Barr virus (virus)	NA	NA	Nucleic Acid	Natural	Viral nucleic acid recognition mediates IFN-Œ± production by pDC.	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Plasmacytoid Dendritic Cells	LRR	Q9NR96.fasta	Q9NR96	1032	This results into the inflammatory response.	ELISA	20178121	2010	Pubchem Assay
PRRID_0490	EBV DNA Click for more detail	Epstein-Barr virus (virus)	NA	NA	Nucleic Acid	Natural	Viral nucleic acid recognition mediates IFN-Œ± production by pDC.	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	Plasmacytoid Dendritic Cells	LRR	Q9NR96.fasta	Q9NR96	1032	This results into the inflammatory response.	ELISA	20178121	2010	Pubchem Assay
PRRID_0491	EBV RNA Click for more detail	Epstein-Barr virus (virus)	NA	NA	Nucleic Acid	Natural	Viral nucleic acid recognition mediates IFN-Œ± production by pDC.	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	Plasmacytoid Dendritic Cells	LRR	Q9NYK1.fasta	Q9NYK1	1049	This results into the inflammatory response.	ELISA	20178121	2010	Pubchem Assay
PRRID_0491	EBV RNA Click for more detail	Epstein-Barr virus (virus)	NA	NA	Nucleic Acid	Natural	Viral nucleic acid recognition mediates IFN-Œ± production by pDC.	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	Plasmacytoid Dendritic Cells	LRR	Q9NYK1.fasta	Q9NYK1	1049	This results into the inflammatory response.	ELISA	20178121	2010	Pubchem Assay
PRRID_0496	Envelope protein Click for more detail	RSV (virus)	MEAVIKAVLTGYPGETSKKDSKKKPPATSKKDPEKTPLLPTRVNYILIIGVLVLCEVTGVRADVHLLEQPGNLWITWASRTGQTDFCLSTQSATSPFQTCLIGIPSPISEGDFKGYVSDNCTTLEPHRLVSRGIPGGPENSTTLTYQKVSCLLLKLNVSLLDEPSELQLLGSQSLPNITNITRIPSVAGGCIGFTPYDSPAGVYGWDRREVTHILLTDPGNNPFFDKASNSSKPFTVVTADRHNLFMGSEYCGAYGYRFWEMYNCSQMRQNWSICQDVWGRGPPENWCTSTGGTWVNQSKEFNETEPFSFTVNCTGSNLGNVSGCCGEPITILPPEAWVDSTQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPNHTDILKILANSSRTGIRRKRSVSHLDDTCSDEVQLWGPTARIFASILAPGVAAAQALKEIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQIVCGNIRKMINNSISYHTEYKKLQKAYGQPESRIV	613	Protein	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leadsto the secretion of the proinfalmmatory cytokines and IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0496	Envelope protein Click for more detail	RSV (virus)	MEAVIKAVLTGYPGETSKKDSKKKPPATSKKDPEKTPLLPTRVNYILIIGVLVLCEVTGVRADVHLLEQPGNLWITWASRTGQTDFCLSTQSATSPFQTCLIGIPSPISEGDFKGYVSDNCTTLEPHRLVSRGIPGGPENSTTLTYQKVSCLLLKLNVSLLDEPSELQLLGSQSLPNITNITRIPSVAGGCIGFTPYDSPAGVYGWDRREVTHILLTDPGNNPFFDKASNSSKPFTVVTADRHNLFMGSEYCGAYGYRFWEMYNCSQMRQNWSICQDVWGRGPPENWCTSTGGTWVNQSKEFNETEPFSFTVNCTGSNLGNVSGCCGEPITILPPEAWVDSTQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPNHTDILKILANSSRTGIRRKRSVSHLDDTCSDEVQLWGPTARIFASILAPGVAAAQALKEIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQIVCGNIRKMINNSISYHTEYKKLQKAYGQPESRIV	613	Protein	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leadsto the secretion of the proinfalmmatory cytokines and IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0499	F protein Click for more detail	Respiratory syncytial virus (virus)	LSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNIC	153	Protein	Natural	Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It coauses the inflammation	NA	20740341	2010	Pubchem Assay
PRRID_0499	F protein Click for more detail	Respiratory syncytial virus (virus)	LSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNIC	153	Protein	Natural	Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It coauses the inflammation	NA	20740341	2010	Pubchem Assay
PRRID_0515	Flagellin Click for more detail	Human respiratory syncytial virus (RSV)	NA	NA	Protein	Natural	Activate NF-Œ∫B	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	Induce IL-1, IL-6, IL-8, and RANTES	NA	20672047	2010	Pubchem Assay
PRRID_0515	Flagellin Click for more detail	Human respiratory syncytial virus (RSV)	NA	NA	Protein	Natural	Activate NF-Œ∫B	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	Induce IL-1, IL-6, IL-8, and RANTES	NA	20672047	2010	Pubchem Assay
PRRID_0527	G-rich oligonucleotides Click for more detail	Human respiratory syncytial virus (RSV)	NA	NA	Protein	Natural	Suppress NF-Œ∫B activation	Toll-like receptor 2/4/9 (TLR2/4/9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0527	G-rich oligonucleotides Click for more detail	Human respiratory syncytial virus (RSV)	NA	NA	Protein	Natural	Suppress NF-Œ∫B activation	Toll-like receptor 2/4/9 (TLR2/4/9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Suppress cytokine production	NA	20672047	2010	NA
PRRID_0532	gB/gH Click for more detail	Human cytomegalovirus (virus)	NA	NA	Glycoprotein	Natural	Activate NF-Œ∫B	Toll-like receptor 2/1 (TLR2/1)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Produce proinflammatory cytokines	NA	20672047	2010	NA
PRRID_0532	gB/gH Click for more detail	Human cytomegalovirus (virus)	NA	NA	Glycoprotein	Natural	Activate NF-Œ∫B	Toll-like receptor 2/1 (TLR2/1)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Produce proinflammatory cytokines	NA	20672047	2010	NA

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