Detailed description page of PRRDB2.0

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PRRID_0496 details
Primary information
PRRIDPRRID_0496
Ligand NameEnvelope protein
SourceRSV (virus)
Sequence of ligandMEAVIKAVLTGYPGETSKKDSKKKPPATSKKDPEKTPLLPTRVNYILIIGVLVLCEVTGVRADVHLLEQPGNLWITWASRTGQTDFCLSTQSATSPFQTCLIGIPSPISEGDFKGYVSDNCTTLEPHRLVSRGIPGGPENSTTLTYQKVSCLLLKLNVSLLDEPSELQLLGSQSLPNITNITRIPSVAGGCIGFTPYDSPAGVYGWDRREVTHILLTDPGNNPFFDKASNSSKPFTVVTADRHNLFMGSEYCGAYGYRFWEMYNCSQMRQNWSICQDVWGRGPPENWCTSTGGTWVNQSKEFNETEPFSFTVNCTGSNLGNVSGCCGEPITILPPEAWVDSTQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPNHTDILKILANSSRTGIRRKRSVSHLDDTCSDEVQLWGPTARIFASILAPGVAAAQALKEIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQIVCGNIRKMINNSISYHTEYKKLQKAYGQPESRIV
Length613
TypeProtein
OccurenceNatural
Role of LigandUpon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCell surface
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the secretion of the proinfalmmatory cytokines and IFN-β
Assay usedNA
PMID20620129
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0496
Ligand NameEnvelope protein
SourceRSV (virus)
Sequence of ligandMEAVIKAVLTGYPGETSKKDSKKKPPATSKKDPEKTPLLPTRVNYILIIGVLVLCEVTGVRADVHLLEQPGNLWITWASRTGQTDFCLSTQSATSPFQTCLIGIPSPISEGDFKGYVSDNCTTLEPHRLVSRGIPGGPENSTTLTYQKVSCLLLKLNVSLLDEPSELQLLGSQSLPNITNITRIPSVAGGCIGFTPYDSPAGVYGWDRREVTHILLTDPGNNPFFDKASNSSKPFTVVTADRHNLFMGSEYCGAYGYRFWEMYNCSQMRQNWSICQDVWGRGPPENWCTSTGGTWVNQSKEFNETEPFSFTVNCTGSNLGNVSGCCGEPITILPPEAWVDSTQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPNHTDILKILANSSRTGIRRKRSVSHLDDTCSDEVQLWGPTARIFASILAPGVAAAQALKEIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQIVCGNIRKMINNSISYHTEYKKLQKAYGQPESRIV
Length613
TypeProtein
OccurenceNatural
Role of LigandUpon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCell surface
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the secretion of the proinfalmmatory cytokines and IFN-β
Assay usedNA
PMID20620129
Year of Publication2010
Pubchem assayPubchem Assay