Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_0205 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0205 |
| Ligand Name | Influenza virus |
| Source | Influenza A (virus) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Whole cell |
| Occurence | Natural |
| Role of Ligand | It leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1. |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Alveolar and bronchial epithelial cells |
| Domain | NA |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | It causes pulmonary inflammation. |
| Assay used | ELISA |
| PMID | 15579900 |
| Year of Publication | 2004 |
| Pubchem assay | Pubchem Assay |
| Primary information | |
|---|---|
| PRRID | PRRID_0205 |
| Ligand Name | Influenza virus |
| Source | Influenza A (virus) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Whole cell |
| Occurence | Natural |
| Role of Ligand | It leads to the activation of NF-kappaB via TRIF adaptor molecule, which results into the secretion of the cytokines IL-8, IL-6, RANTES (regulated on activation normal T cell expressed and secreted), and interferon- and the up-regulation of the major adhesion molecule ICAM-1. |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Alveolar and bronchial epithelial cells |
| Domain | NA |
| Sequence of Receptor | O15455.fasta |
| Swiss prot ID | O15455 |
| Length Of Receptor | 904 |
| Function | It causes pulmonary inflammation. |
| Assay used | ELISA |
| PMID | 15579900 |
| Year of Publication | 2004 |
| Pubchem assay | Pubchem Assay |