Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_2048Flagellin

Click for more detail

BacteriaMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR495ProteinNaturalNANAIPNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2048Flagellin

Click for more detail

BacteriaMAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR495ProteinNaturalNANAIPNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2152Hemozoin

Click for more detail

Plasmodium falciparum (others)CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.[Fe+5].[Fe+5].[Fe+5].[Fe+5]NAPattern-associated molecular patterns (PAMPs)NaturalPlasmodium falciparum-infected erythro- cytes, that co-purifies with the parasite product hemozoin, stimulates NOD2 in a RIP2/CARD9- dependent manner to drive nitric oxide production by macrophagesNucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8K3Z0.fastaQ8K3Z01020Hemozoin-mediated induction of NOSNA288235102017Pubchem_assay
PRRID_2152Hemozoin

Click for more detail

Plasmodium falciparum (others)CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N+]4=[Fe])C=C5C(=C(C(=N5)C=C1[N-]2)C=C)C)C=C)C)C(=C3CCC(=O)[O-])C)CCC(=O)O.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)CCC(=O)O)CCC(=O)[O-])C)C(=C3C)C=C)C=C.[Fe+5].[Fe+5].[Fe+5].[Fe+5]NAPattern-associated molecular patterns (PAMPs)NaturalPlasmodium falciparum-infected erythro- cytes, that co-purifies with the parasite product hemozoin, stimulates NOD2 in a RIP2/CARD9- dependent manner to drive nitric oxide production by macrophagesNucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8K3Z0.fastaQ8K3Z01020Hemozoin-mediated induction of NOSNA288235102017Pubchem_assay
PRRID_2155hepta- noyl-d-Glu-meso-DAP-d-Ala (FK565)

Click for more detail

NACC(C)(C)OC(=O)CCC(C(=O)O)NC(=O)OC(C)(C)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2155hepta- noyl-d-Glu-meso-DAP-d-Ala (FK565)

Click for more detail

NACC(C)(C)OC(=O)CCC(C(=O)O)NC(=O)OC(C)(C)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2160Histone

Click for more detail

Nucleus (others)NANADamage-associated molecular patterns (DAMPs)Naturalnvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANANANANANANANA292901392017NA
PRRID_2160Histone

Click for more detail

Nucleus (others)NANADamage-associated molecular patterns (DAMPs)Naturalnvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANANANANANANANA292901392017NA
PRRID_2199Hyaluronan

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the production of TNF-α, IL-1β and IL-12 by dendritic cellsNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Humandendritic cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2199Hyaluronan

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the production of TNF-α, IL-1β and IL-12 by dendritic cellsNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Humandendritic cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2202Hyaluronic acid

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the maturation of mouse and human dendritic cells,Nod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanEndothelial cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2202Hyaluronic acid

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the maturation of mouse and human dendritic cells,Nod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanEndothelial cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2207Hyaluronic acid

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the production of TNF-α, IL-1β and IL-12 by dendritic cellsNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanEndothelial cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2207Hyaluronic acid

Click for more detail

NACC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)ONADamage-associated molecular patterns (DAMPs)NaturalInduce the production of TNF-α, IL-1β and IL-12 by dendritic cellsNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanEndothelial cellsNAQ96P20.fastaQ96P201036NANA289610192017Pubchem_assay
PRRID_2208IgA protease (ST-11 N. meningitidis)

Click for more detail

NANANANANaturalApoptosis in epithelial cellsNf-κb (intracellular signalling)NOD-like receptor (NLR)NA(Cytoplasmic /nuclear)NANANANANANA283342032017NA
PRRID_2208IgA protease (ST-11 N. meningitidis)

Click for more detail

NANANANANaturalApoptosis in epithelial cellsNf-κb (intracellular signalling)NOD-like receptor (NLR)NA(Cytoplasmic /nuclear)NANANANANANA283342032017NA
PRRID_2213intracellular bacterial lipopolysaccharides (LPS)

Click for more detail

BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 1Q9Y239.fastaQ9Y239953NANA290662552017Pubchem_assay
PRRID_2213intracellular bacterial lipopolysaccharides (LPS)

Click for more detail

BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 1Q9Y239.fastaQ9Y239953NANA290662552017Pubchem_assay
PRRID_2214intracellular bacterial lipopolysaccharides (LPS)

Click for more detail

BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2214intracellular bacterial lipopolysaccharides (LPS)

Click for more detail

BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2308LMW-HA

Click for more detail

Glycosaminoglycan (others)NANADamage-associated molecular patterns (DAMPs)Naturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANANANANANANANA292901392017NA
PRRID_2308LMW-HA

Click for more detail

Glycosaminoglycan (others)NANADamage-associated molecular patterns (DAMPs)Naturalinvolved in the resolution and fine-tuning of inflammation by orchestrating the production of anti-inflammatory mediators that are required for the resolution of tissue inflammation and the transition to acquired immunityNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)NANANANANANANANA292901392017NA
PRRID_2313ATP

Click for more detail

BacteriaC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)ONAProteinNaturalNANALP3/ cryopyrinNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2313ATP

Click for more detail

BacteriaC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)ONAProteinNaturalNANALP3/ cryopyrinNOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2321M-Tri-DAP

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)NNAPeptidoglycanSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2321M-Tri-DAP

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)NNAPeptidoglycanSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2332MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)NANANANANANANANA288015212017NA
PRRID_2332MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)NANANANANANANANA288015212017NA
PRRID_2333MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)RatHippocampusNAD9I2G4 .fastaD9I2G41218NLRP1 inflammasome activation in agingNA288015212017Pubchem_assay
PRRID_2333MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)RatHippocampusNAD9I2G4 .fastaD9I2G41218NLRP1 inflammasome activation in agingNA288015212017Pubchem_assay
PRRID_2334MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288015212017Pubchem_assay
PRRID_2334MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288015212017Pubchem_assay
PRRID_2335MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Humanhippocampus (neurons)NAQ9C000.fastaQ9C0001473protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2335MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Humanhippocampus (neurons)NAQ9C000.fastaQ9C0001473protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2336MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Micemodels of ADNAQ2LKU9.fastaQ2LKU91182protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2336MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Micemodels of ADNAQ2LKU9.fastaQ2LKU91182protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2337MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ2LKU9.fastaQ2LKU91182protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2337MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ2LKU9.fastaQ2LKU91182protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2338MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)HumanBrainNAQ9C000.fastaQ9C0001473protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2338MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)HumanBrainNAQ9C000.fastaQ9C0001473protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2339MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2339MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2340MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2340MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2341MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNANANANAprotein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017NA
PRRID_2341MDP (muramyldipeptide)

Click for more detail

Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNANANANAprotein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017NA
PRRID_2349muramyl di- , glycosaminyl muramyl dipeptide

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptidoglycanSyntheticNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)NANANANANANANANA292073442017NA
PRRID_2349muramyl di- , glycosaminyl muramyl dipeptide

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptidoglycanSyntheticNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)NANANANANANANANA292073442017NA
PRRID_2350muramyl dipeptide (MDP)

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2350muramyl dipeptide (MDP)

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2351muramyl dipeptide (MDP)

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceNANAQ8K3Z0.fastaQ8K3Z01020NANA290389562017Pubchem_assay
PRRID_2351muramyl dipeptide (MDP)

Click for more detail

BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceNANAQ8K3Z0.fastaQ8K3Z01020NANA290389562017Pubchem_assay
PRRID_2352Muropeptides

Click for more detail

Gram negative Bacteria (Bacteria)NANAPeptidoglycanNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA292073442017NA
PRRID_2352Muropeptides

Click for more detail

Gram negative Bacteria (Bacteria)NANAPeptidoglycanNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA292073442017NA
PRRID_2353muropeptides with a meso-diaminopimelate residue (meso-DAP)

Click for more detail

Gram negative bacteria(Leptospira spp.)C(CC(C(=O)O)N)CC(C(=O)O)NNANANaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceNANAQ8BHB0.fastaQ8BHB0953NANA290389562017Pubchem_assay
PRRID_2353muropeptides with a meso-diaminopimelate residue (meso-DAP)

Click for more detail

Gram negative bacteria(Leptospira spp.)C(CC(C(=O)O)N)CC(C(=O)O)NNANANaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceNANAQ8BHB0.fastaQ8BHB0953NANA290389562017Pubchem_assay
PRRID_2361N-acetylmuramic acid

Click for more detail

BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2361N-acetylmuramic acid

Click for more detail

BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2362N-acyl glutamyl DAP

Click for more detail

NANANAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2362N-acyl glutamyl DAP

Click for more detail

NANANAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2414NA

Click for more detail

NANANANANANANod-like receptor C4 (NLRC4)NOD-like receptor (NLR)HumanNANLR family CARD domain-containing protein 4,Q9NPP4.fastaQ9NPP41024NANA290662552017Pubchem_assay
PRRID_2414NA

Click for more detail

NANANANANANANod-like receptor C4 (NLRC4)NOD-like receptor (NLR)HumanNANLR family CARD domain-containing protein 4,Q9NPP4.fastaQ9NPP41024NANA290662552017Pubchem_assay
PRRID_2451NA

Click for more detail

Human cytomegalovirus (virus)NANANANANANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8K3Z0.fastaQ8K3Z01020Restriction of viral replicationNA288235102017Pubchem_assay
PRRID_2451NA

Click for more detail

Human cytomegalovirus (virus)NANANANANANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8K3Z0.fastaQ8K3Z01020Restriction of viral replicationNA288235102017Pubchem_assay
PRRID_2452NA

Click for more detail

Human cytomegalovirus (virus)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953Restriction of viral replicationNA288235102017Pubchem_assay
PRRID_2452NA

Click for more detail

Human cytomegalovirus (virus)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953Restriction of viral replicationNA288235102017Pubchem_assay
PRRID_2453NA

Click for more detail

Plasmodium berghei (fungi)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953Induction of IL-1b, KC, IFNgNA288235102017Pubchem_assay
PRRID_2453NA

Click for more detail

Plasmodium berghei (fungi)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)MiceMacrophagesnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953Induction of IL-1b, KC, IFNgNA288235102017Pubchem_assay
PRRID_2454NA

Click for more detail

Trypanosoma Cruzi (others)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)Micespleen and heartnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953NOD1-KO mice are highly susceptible to infectionNA288235102017Pubchem_assay
PRRID_2454NA

Click for more detail

Trypanosoma Cruzi (others)NANANANANANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)Micespleen and heartnucleotide-binding oligomerization domainQ8BHB0.fastaQ8BHB0953NOD1-KO mice are highly susceptible to infectionNA288235102017Pubchem_assay
PRRID_2458NA

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micesubstantia nigraNAQ8R4B8.fastaQ8R4B81033protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2458NA

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micesubstantia nigraNAQ8R4B8.fastaQ8R4B81033protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2499Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288015212017Pubchem_assay
PRRID_2499Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288015212017Pubchem_assay
PRRID_2500Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2500Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2501Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2501Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2502Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNAD4A523.fastaD4A5231035protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2502Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNAD4A523.fastaD4A5231035protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2503Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micesubstantia nigraNAQ8R4B8.fastaQ8R4B81033protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2503Nigericin

Click for more detail

NANANAPattern-associated molecular patterns (PAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micesubstantia nigraNAQ8R4B8.fastaQ8R4B81033protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2533pathogen ssRNA

Click for more detail

flu virus, SeV and bacteriaNANAPattern-associated molecular patterns (PAMPs)Naturalpotassium efflux-NEK7 involved NLRP3 inflammasome complexNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanCytoplasm. Ubiquitously expressedNAQ96P20.fastaQ96P201036ASC-inflammasome- caspase-1-IL-1/IL-18NA283749032017Pubchem_assay
PRRID_2533pathogen ssRNA

Click for more detail

flu virus, SeV and bacteriaNANAPattern-associated molecular patterns (PAMPs)Naturalpotassium efflux-NEK7 involved NLRP3 inflammasome complexNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanCytoplasm. Ubiquitously expressedNAQ96P20.fastaQ96P201036ASC-inflammasome- caspase-1-IL-1/IL-18NA283749032017Pubchem_assay
PRRID_2543Peptidoglycan (PGN)

Click for more detail

P. gulae (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalCauses inflammation and activation of NOD2.Nucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceHEK cellsNAQ8K3Z0.fastaQ8K3Z01020activate NF-κB.NA286300662017Pubchem_assay
PRRID_2543Peptidoglycan (PGN)

Click for more detail

P. gulae (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalCauses inflammation and activation of NOD2.Nucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)MiceHEK cellsNAQ8K3Z0.fastaQ8K3Z01020activate NF-κB.NA286300662017Pubchem_assay
PRRID_2547peptidoglycan (PGN)-derived muropeptides

Click for more detail

BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNANANaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 1Q9Y239.fastaQ9Y239953NANA290662552017Pubchem_assay
PRRID_2547peptidoglycan (PGN)-derived muropeptides

Click for more detail

BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNANANaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 1Q9Y239.fastaQ9Y239953NANA290662552017Pubchem_assay
PRRID_2551PG-derived molecules (iE-DAP and MDP respectively

Click for more detail

BacteriaN[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=ONAProteinNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2551PG-derived molecules (iE-DAP and MDP respectively

Click for more detail

BacteriaN[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=ONAProteinNaturalNANucleotide Binding Oligomerization Domain Containing 1 (Nod1)NOD-like receptor (NLR)NANANANANANANANA280630152017NA
PRRID_2579Quil-A

Click for more detail

Quillaja sponaria tree (plant)NANAsteroidal or triterpenoid aglyconesNaturalAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsQ96P20.fastaQ96P201036triggering production of β-defensins via an NF-κB signaling pathwayNA287764162017Pubchem_assay
PRRID_2579Quil-A

Click for more detail

Quillaja sponaria tree (plant)NANAsteroidal or triterpenoid aglyconesNaturalAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsQ96P20.fastaQ96P201036triggering production of β-defensins via an NF-κB signaling pathwayNA287764162017Pubchem_assay
PRRID_2595ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288051212017Pubchem_assay
PRRID_2595ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)MiceMicrogliaNAQ8R4B8.fastaQ8R4B81033NLRP3 inflammasome activation in AD modelsNA288051212017Pubchem_assay
PRRID_2596ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2596ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Micecortical neurons (cell culture, stroke model)NAQ8R4B8.fastaQ8R4B81033protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2597ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2597ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2598ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNAD4A523.fastaD4A5231035protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay
PRRID_2598ROS

Click for more detail

NANANADamage-associated molecular patterns (DAMPs)NaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)Ratprimary astrocytesNAD4A523.fastaD4A5231035protein ‚Üë, activation of NLRP3 inflammasome in PD modelsNA288015212017Pubchem_assay