| Primary information |
|---|
| PRRID | PRRID_2579 |
| Ligand Name | Quil-A |
| Source | Quillaja sponaria tree (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | steroidal or triterpenoid aglycones |
| Occurence | Natural |
| Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
| Name of receptor | Nod-like receptor P3 (NLRP3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Intracellular |
| Domain | C-terminal leucine-rich regions and NOD domains |
| Sequence of Receptor | Q96P20.fasta |
| Swiss prot ID | Q96P20 |
| Length Of Receptor | 1036 |
| Function | triggering production of β-defensins via an NF-κB signaling pathway |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_2579 |
| Ligand Name | Quil-A |
| Source | Quillaja sponaria tree (plant) |
| Sequence of ligand | NA |
| Length | NA |
| Type | steroidal or triterpenoid aglycones |
| Occurence | Natural |
| Role of Ligand | Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokines |
| Name of receptor | Nod-like receptor P3 (NLRP3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Intracellular |
| Domain | C-terminal leucine-rich regions and NOD domains |
| Sequence of Receptor | Q96P20.fasta |
| Swiss prot ID | Q96P20 |
| Length Of Receptor | 1036 |
| Function | triggering production of β-defensins via an NF-κB signaling pathway |
| Assay used | NA |
| PMID | 28776416 |
| Year of Publication | 2017 |
| Pubchem assay | Pubchem_assay |