Detailed description page of PRRDB2.0

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PRRID_2334 details
Primary information
PRRIDPRRID_2334
Ligand NameMDP (muramyldipeptide)
SourceGram-negative and Gram-positive bacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of LigandNA
Name of receptorNod-like receptor P3 (NLRP3)
Type of receptorNOD-like receptor (NLR)
Source Mice
LocalizationMicroglia
DomainNA
Sequence of ReceptorQ8R4B8.fasta
Swiss prot IDQ8R4B8
Length Of Receptor1033
FunctionNLRP3 inflammasome activation in AD models
Assay usedNA
PMID28801521
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2334
Ligand NameMDP (muramyldipeptide)
SourceGram-negative and Gram-positive bacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of LigandNA
Name of receptorNod-like receptor P3 (NLRP3)
Type of receptorNOD-like receptor (NLR)
Source Mice
LocalizationMicroglia
DomainNA
Sequence of ReceptorQ8R4B8.fasta
Swiss prot IDQ8R4B8
Length Of Receptor1033
FunctionNLRP3 inflammasome activation in AD models
Assay usedNA
PMID28801521
Year of Publication2017
Pubchem assayPubchem_assay