The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	59% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_2	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	56% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_3	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	49% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_4	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_5	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_6	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_7	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	50 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_8	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	100 MOI	60% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_9	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	Grown to 70% confluence	NA	MTT assay	200 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_10	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_11	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_12	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_13	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	100% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_14	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	95% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_15	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_16	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	10 MOI	77% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_17	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	50 MOI	72% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_18	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIAPaCa-2	Grown to 70% confluence	NA	MTT assay	100 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_19	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_20	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_21	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_22	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	100% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_23	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	95% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_24	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_25	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	77% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_26	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	72% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_27	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_28	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	80% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_29	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	78% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_30	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	40% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_31	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	90% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_32	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	82% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_33	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	84% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_34	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	5 MOI	89% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_35	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_36	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human pancreatic cancer cell line	AsPC-1	Grown to 70% confluence	NA	MTT assay	20 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_37	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MIA PaCa-2 cell line 5.0E+6 cells	2.0E+10 VP (on 0, 2, and 4 days)	Slight hepatotoxicity	Reduction in tumor volume to 230 cubic millimeter compared to control 300 cubic millimeter after 46 days	Intravenously	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_38	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MIA PaCa-2 cell line 5.0E+4 cells	2.0E+10 VP (on 0, 2, and 4 days)	NA	Reduction in tumor volume to 198 cubic millimeter compared to control 300 cubic millimeter after 46 days	Intravenously	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_39	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MIA PaCa-2 cell line 5.0E+4 cells	2.0E+10 VP (on 0, 2, and 4 days)	NA	Reduction in tumor volume to 100 cubic millimeter compared to control 300 cubic millimeter after 46 days	Intravenously	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_40	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	13% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_41	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	54% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_42	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_43	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	22% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_44	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_45	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_46	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Female FVB/NCr mice isograft for 5.0E+6 cells ED-1 murine lung cancer cell lines	1.5E+9 IFU (on 0, 2, 4 and 6 days)	NA	Reduction in tumor volume to 52 cubic millimeter compared to control 150 cubic millimeter after 36 days	Intratumorally	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_47	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	57% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_48	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.67 CDI	MTT assay	0.1 MOI	24% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_49	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.46 CDI	MTT assay	0.1 MOI	16% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_50	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.88 CDI	MTT assay	0.1 MOI	26% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_51	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.79 CDI	MTT assay	0.1 MOI	25% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_52	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.81 CDI	MTT assay	0.1 MOI	28% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_53	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_54	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.27 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_55	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.31 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_56	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.33 CDI	MTT assay	0.1 MOI	6% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_57	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.89 CDI	MTT assay	0.1 MOI	12% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_58	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.78 CDI	MTT assay	0.1 MOI	10% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_59	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_60	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	0.1 MOI	90% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_61	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	1 MOI	40% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_62	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	10 MOI	2% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_63	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_64	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.01 MOI	90% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_65	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.1 MOI	60% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_66	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_67	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	10 MOI	1% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_68	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_69	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_70	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.1 MOI	96% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_71	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	1 MOI	80% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_72	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	10 MOI	20% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_73	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_74	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_75	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	1 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_76	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	10 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_77	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_78	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_79	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	1 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_80	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	10 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_81	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_82	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	0.1 MOI	85% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_83	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	1 MOI	35% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_84	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (YB-1 gene knockdown)	NA	NA	Crystal violet staining	10 MOI	1% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_85	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_86	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.01 MOI	90% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_87	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	0.1 MOI	20% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_88	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	1 MOI	2% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_89	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged YB-1 gene overexpressed)	NA	NA	Crystal violet staining	10 MOI	1% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_90	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_91	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_92	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	0.1 MOI	94% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_93	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	1 MOI	75% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_94	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human breast cancer line	MCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)	NA	NA	Crystal violet staining	10 MOI	16% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_95	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	0.01 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462
OV_96	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	0.1 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462
OV_97	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	1 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462
OV_98	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	10 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462
OV_99	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	0.01 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462
OV_100	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Clinical lung adenocarcinoma tissue (Primary cancer cells, Stage IA)	0.1 MOI	NA	100% cancer cell viability	NA	NA	NA	NA	26515462