Detailed description page of Selected OV_ID


OV_12 details
Primary information
OV_IDOV_12
Virus Name Adenovirus
StrainoAd/DCN/LRP
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeInsertional mutant for DCN and LRP gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic cancer cell line
Cell lineMIAPaCa-2
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration100 MOI
In-vitro result38% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInhibits Wnt/β-catenin and TGF-β1 signaling pathways
Immunogenic effectIL-6 production increased by 3 folds as compared to normal
Clinical trialNA
PMID26471393