Detailed description page of Selected OV_ID


OV_78 details
Primary information
OV_IDOV_78
Virus Name Adenovirus
StrainAdLacZ
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeE1/E3-deleted mutant
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman breast cancer line
Cell lineMCF-7 (HA-tagged mutant YB-1(S102A) gene overexpression, mutation at Akt phosphorylation site which leads to failed nuclear translocation)
Concentration of cell line0
In-vitro toxicityNA
AssayCrystal violet staining
In-vitro virus concentration0.1 MOI
In-vitro result100% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26515462