| Primary information |
|---|
| OV_ID | OV_44 |
| Virus Name | Adenovirus |
| Strain | Ad dl1520 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Murine lung cancer cell line |
| Cell line | ED-1 |
| Concentration of cell line | 0 |
| In-vitro toxicity | Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI |
| Assay | MTT assay |
| In-vitro virus concentration | 10 MOI |
| In-vitro result | 55% cancer cell viability |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 26475304 |