The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4040	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4041	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	42% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4042	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4043	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	2 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4044	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	8 HAU	22% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4045	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	16 HAU	20% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4046	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4047	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	42% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4048	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	39% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4049	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	2 HAU	79% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4050	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	8 HAU	80% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4051	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	16 HAU	80% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4052	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4053	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	35% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4054	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4055	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	2 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4056	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	8 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4057	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	16 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4058	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4059	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	20% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4060	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	20% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4061	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	2 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4062	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	8 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4063	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	16 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4064	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	2 HAU	68% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4065	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4066	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	State centre for virology and biotechnology, Russia	Human colon carcinoma cell line	HCT-116	10000 cells per well	NA	MTT assay	16 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4067	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4068	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	8 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4069	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Institute of clinical and experimental lymphology, Russia	Human epitheloid cervix carcinoma	HeLa	10000 cells per well	NA	MTT assay	16 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4070	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	40% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4071	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4072	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4073	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	2 HAU	90% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4074	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	8 HAU	90% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4075	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Russian academy of science, Russia	Human breast cancer adenocarcinoma cell line	MCF-7	10000 cells per well	NA	MTT assay	16 HAU	80% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4076	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	NA	NA	NA	NA	NA	SCID mice xenograft for A459 cell (3.5E+6)	16 HAU	NA	4.2 fold decrease in tumor size compared to control after 15th day	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4369	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human skin metastasis	SK-MEL-2	2000 cells per well	NA	Luciferase based ATP assay	0.013 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4370	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human axillary node metastasis	SKMEL-5	1000 cells per well	NA	Luciferase based ATP assay	0.017 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4371	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human filamin-1 transfected M2 skin melanoma cell line	A7	500 cells per well	NA	Luciferase based ATP assay	0.020 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4372	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human lung metastasis cell line	MALME-3M	1000 cells per well	NA	Luciferase based ATP assay	0.038 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4373	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UACC-257	1000 cells per well	NA	Luciferase based ATP assay	0.083 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4374	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	SK-MEL-28	500 cells per well	NA	Luciferase based ATP assay	0.257 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4375	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lymph node metastasis cell line	SKMEL-3	1000 cells per well	NA	Luciferase based ATP assay	0.286 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4376	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human bowes melanoma cell line	HMCB	750 cells per well	NA	Luciferase based ATP assay	0.310 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4377	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human lymph node metastasis cell line	LOX-IMVI	1000 cells per well	NA	Luciferase based ATP assay	0.788 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4378	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UCSD-24L	500 cells per well	NA	Luciferase based ATP assay	0.798 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4379	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human primary melanoma cell line	A375	250 cells per well	NA	Luciferase based ATP assay	0.948 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4380	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UACC-62	500 cells per well	NA	Luciferase based ATP assay	1 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4381	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lymph node metastasis cell line	RPMI-7951	500 cells per well	NA	Luciferase based ATP assay	2.565 MOI	50% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4382	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human skin metastasis	SK-MEL-2	2000 cells per well	NA	Luciferase based ATP assay	0.058 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4383	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human axillary node metastasis	SKMEL-5	1000 cells per well	NA	Luciferase based ATP assay	0.065 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4384	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human filamin-1 transfected M2 skin melanoma cell line	A7	500 cells per well	NA	Luciferase based ATP assay	0.363 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4385	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human lung metastasis cell line	MALME-3M	1000 cells per well	NA	Luciferase based ATP assay	0.155 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4386	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UACC-257	1000 cells per well	NA	Luciferase based ATP assay	0.370 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4387	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	SK-MEL-28	500 cells per well	NA	Luciferase based ATP assay	0.922 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4388	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lymph node metastasis cell line	SKMEL-3	1000 cells per well	NA	Luciferase based ATP assay	1.80 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4389	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human bowes melanoma cell line	HMCB	750 cells per well	NA	Luciferase based ATP assay	6.10 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4390	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human lymph node metastasis cell line	LOX-IMVI	1000 cells per well	NA	Luciferase based ATP assay	6 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4391	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UCSD-24L	500 cells per well	NA	Luciferase based ATP assay	2.25 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4392	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human primary melanoma cell line	A375	250 cells per well	NA	Luciferase based ATP assay	4.43 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4393	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	NCI	Human malignant melanoma cell line	UACC-62	500 cells per well	NA	Luciferase based ATP assay	2.46 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4394	Newcastle disease virus	MTH-68/H	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lymph node metastasis cell line	RPMI-7951	500 cells per well	NA	Luciferase based ATP assay	8.80 MOI	80% cancer cell death	No	No	NA	No response	NA	ER stress and apoptotic pathway	IFN production increased	NA	26408702
OV_4490	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.0001 MOI	50% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4491	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.01 MOI	30% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4492	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4493	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4494	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	10 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4495	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.0001 MOI	80% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4496	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.01 MOI	38% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4497	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.1 MOI	15% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4498	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4499	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	10 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4500	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.0001 MOI	50% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4501	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.01 MOI	20% cell viablity after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4502	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	0.1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4503	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4504	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	ATCC	Human fibroblast sarcoma cell line	HT1080	5.0E+3 cells per well	NA	Cell titer glo kit	10 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4505	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for HT1080 (5.0E+6)	2.0E+7 pfu	NA	Tumor volume reduced to 300 cubic mm after 25 days compared to control 800 cubic mm	Intratumoral	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4506	Newcastle disease virus	73T-S-Km	RNA	Paramyxoviridae	Insertion of HNKMKS sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for HT1080 (5.0E+6)	2.0E+7 pfu	NA	Tumor volume reduced to below 100 cubic mm after 25 days compared to control 800 cubic mm	Intratumoral	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4507	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for HT1080 (5.0E+6)	2.0E+7 pfu	NA	Tumor volume reduced to 300 cubic mm after 25 days compared to control 800 cubic mm	Intratumoral	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4508	Newcastle disease virus	73T-R-198	RNA	Paramyxoviridae	Insertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic nude mice xenograft for HT1080 (5.0E+6)	1.0E+8 pfu	NA	Tumor volume reduced to below 500 cubic mm compared to control 1000 cubic mm after 25 days	Intravenous	NA	Induced expression of Type 1 IFN, NK cells and macrophages	NA	27009956
OV_4945	Newcastle disease virus	NDV/Anh	RNA	Paramyxoviridae	None	Yes	No	No	Harbin phamaceutical group bioengineering	NA	NA	NA	NA	NA	NA	NA	Nude mice xenograft for H22 cell line (1.0E+5 cells)	1.0E+7 pfu every other day for four times	NA	Average volume in control mice was 3401.25 cubic mm and decreased to 1489.97 cubuc mm in treated mice	Intratumoral	NA	Activate T cells	NA	27174862
OV_4946	Newcastle disease virus	NDV/Anh-IL2	RNA	Paramyxoviridae	Insertion of IL-2 gene between HN and L gene of pAnh-wt	Yes	No	Expressing Il-2 gene	Harbin phamaceutical group bioengineering	NA	NA	NA	NA	NA	NA	NA	Nude mice xenograft for H22 cell line (1.0E+5 cells)	1.0E+7 pfu every other day for four times	NA	Average volume in control mice was 3401.25 cubic mm and decreased to 420.67 cubuc mm in treated mice, while 3 out of 6 complete regressed tumor volume	Intratumoral	NA	Activate T cells	NA	27174862
OV_5334	Newcastle disease virus	NDV/Anh-TRAIL	RNA	Paramyxoviridae	Virus insertion for TRAIL gene	Yes	No	No	China Xiehe Medical University	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	56.7% cells remain viable	No	No	NA	No response	NA	Virus induced apoptosis as measured by TUNEL assay	Caspase 3 pathway are activated	NA	28246027
OV_5335	Newcastle disease virus	NDV/Anh-TRAIL	RNA	Paramyxoviridae	Virus insertion for TRAIL gene	Yes	No	No	China Xiehe Medical University	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	43.2% cells remain viable	No	No	NA	No response	NA	Virus induced apoptosis as measured by TUNEL assay	Caspase 3 pathway are activated	NA	28246027
OV_5336	Newcastle disease virus	NDV/Anh-TRAIL	RNA	Paramyxoviridae	Virus insertion for TRAIL gene	Yes	No	No	China Xiehe Medical University	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	1 MOI	29.6% cells remain viable	No	No	NA	No response	NA	Virus induced apoptosis as measured by TUNEL assay	Caspase 3 pathway are activated	NA	28246027
OV_5337	Newcastle disease virus	NDV/Anh-TRAIL	RNA	Paramyxoviridae	Virus insertion for TRAIL gene	Yes	No	No	China Xiehe Medical University	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	10 MOI	20.8% cell growth inhibition	No	No	NA	No response	NA	Virus induced apoptosis as measured by TUNEL assay	Caspase 3 pathway are activated	NA	28246027
OV_5338	Newcastle disease virus	NDV/Anh-TRAIL	RNA	Paramyxoviridae	Virus insertion for TRAIL gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Kumming mice implanted for 5.0E+5 H22 cells	1.0E+7 pfu	NA	Reduction in tumor volume to 10 cubic mm compared to control 3500 cubic mm after 14 days	Intratumoral	Virus induced apoptosis as measured by TUNEL assay	Caspase 3 pathway are activated	NA	28246027
OV_5339	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human nonsmall cell lung carcinoma	A549	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	16% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5340	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	37% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5341	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human glioblastoma multiforme	U-87 MG	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	19% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5342	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human mammary gland adenocarcinoma	MDA-MB-453	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	35% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5343	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human glioblastoma multiforme	T98G	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	29% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5344	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human mammary gland adenocarcinoma	MCF-7	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	44% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5591	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human fibrosarcoma cell line	HT1080	80% confluency	NA	MTT assay	2 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5592	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human pancreatic carcinoma cell line	PANC-1	80% confluency	NA	MTT assay	3 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5593	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human renal carcinoma cell line	CAKI-1	80% confluency	NA	MTT assay	8 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5594	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human renal carcinoma cell line	CAKI-1	80% confluency	NA	MTT assay	11 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5595	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human renal carcinoma cell line	A498	80% confluency	NA	MTT assay	15 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426