Detailed description page of Selected OV_ID


OV_4503 details
Primary information
OV_IDOV_4503
Virus Name Newcastle disease virus
Strain73T-R-198
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeInsertion of HNRTKR sequence in fusogenic site between 111 -116 nucleotide
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman fibroblast sarcoma cell line
Cell lineHT1080
Concentration of cell line5
In-vitro toxicityNA
AssayCell titer glo kit
In-vitro virus concentration1 MOI
In-vitro result100% cell death after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectInduced expression of Type 1 IFN, NK cells and macrophages
Clinical trialNA
PMID27009956